Results 51 to 60 of about 154,788 (267)
Layer- and Cell Type-Specific Modulation of Excitatory Neuronal Activity in the Neocortex
Frontiers in Neuroanatomy, 2018 From an anatomical point of view the neocortex is subdivided into up to six layers depending on the cortical area. This subdivision has been described already by Meynert and Brodmann in the late 19/early 20.
Gabriele Radnikow +3 more
doaj +1 more source
Multiscale Circuit Architecture Associated With Memory Dysfunction in Temporal Lobe Epilepsy
Advanced Science, EarlyView.A multiscale precision‐mapping framework reveals that memory impairment in temporal lobe epilepsy arises from the convergence of focal medial temporal pathology, strategic white matter disconnection, and limbic‐centered metabolic network dysfunction.
Jiajie Mo +12 more
wiley +1 more source
Molecules, 2010 Ginkgo biloba is widely used in folk medicine. Patients very often use the plant preparation with no concern for purity. They also tend to increase the dosage by themselves and this may result in certain insufficiently researched acute effects.
Svetlana Trivic +5 more
doaj +1 more source
Advanced Science, EarlyView.We constructed a brain‐targeted AFn‐DPZ nanodrug delivery system and identified EphB1 as its receptor on the blood‐brain barrier (BBB). This system facilitates drug transport across the BBB and thereby ameliorates cognitive impairment in Alzheimer's disease.
Shilin Wen +5 more
wiley +1 more source
Advanced Intelligent Discovery, EarlyView.Predictive models successfully screen nanoparticles for toxicity and cellular uptake. Yet, complex biological dynamics and sparse, nonstandardized data limit their accuracy. The field urgently needs integrated artificial intelligence/machine learning, systems biology, and open‐access data protocols to bridge the gap between materials science and safe ...
Mariya L. Ivanova +4 more
wiley +1 more source
Pharmacology Research & PerspectivesGastrin‐releasing peptide (GRP) and neuromedin B (NMB) are found in the stomach's myenteric plexus and muscular layers. When exogenously administered, they contract stomach muscle in several species, but their ability to modulate enteric nerve functions ...
Diego Currò +2 more
doaj +1 more source
Animal Models and Experimental Medicine, EarlyView.The research strategy for pharmacodynamics, serum pharmacochemistry, metabolomics, and network pharmacology analysis method in intervention effects of LTT are illustrated. Abstract Background Liujing Toutong tablet (LTT) is a traditional Chinese patent medicine.
Zihan Yu +10 more
wiley +1 more source
Laboratory Animal Research, 2018 This study was performed to investigate the effect of a concentrate of fermented wild ginseng root culture (HLJC0701) on memory improvement in the scopolamine (SPL)-induced memory-deficient mouse model.
Song-Hee Han +5 more
doaj +1 more source
Innervation of the tubarial glands: A hypothesis‐driven anatomical review
The Anatomical Record, EarlyView.Abstract The tubarial glands have been described as a macroscopic bilateral glandular complex in the posterolateral nasopharynx near the torus tubarius and the pharyngeal opening of the Eustachian tube. Since their recognition on prostate‐specific membrane antigen‐based imaging, their anatomical classification has remained debated, with converging ...
Mugurel Constantin Rusu +2 more
wiley +1 more source
Sympathetic Hyperactivity and Age Affect Segregation and Expression of Neurotransmitters
Frontiers in Cellular Neuroscience, 2018 Sympathetic neurons of the rat superior cervical ganglion (SCG) can segregate their neurotransmitters and co-transmitters to separate varicosities of single axons.
Candelaria Merino-Jiménez +5 more
doaj +1 more source