Results 61 to 70 of about 155,024 (264)
Sympathetic Hyperactivity and Age Affect Segregation and Expression of Neurotransmitters
Frontiers in Cellular Neuroscience, 2018 Sympathetic neurons of the rat superior cervical ganglion (SCG) can segregate their neurotransmitters and co-transmitters to separate varicosities of single axons.
Candelaria Merino-Jiménez +5 more
doaj +1 more source
Advanced Science, EarlyView.Schematic diagrams illustrating the breakthrough in the screening of AChE inhibitors from LBL, and the research process of the pharmacodynamics of the NCP are presented. ABSTRACT Current Alzheimer's drugs exhibit limited effectiveness, highlighting the necessity for multi‐target treatments.
Yuping Sa +11 more
wiley +1 more source
Frontiers in Neural Circuits, 2018 Acetylcholine (ACh) is believed to act as a neuromodulator in cortical circuits that support cognition, specifically in processes including learning, memory consolidation, vigilance, arousal and attention. The cholinergic modulation of cortical processes
Jennifer J. Coppola, Anita A. Disney
doaj +1 more source
Advanced Science, EarlyView.A ZIF‐90 nanocarrier delivers dinotefuran and suppresses NlABCG3 and NlABCH1 in resistant Nilaparvata lugens. This system combines pH/ATP‐triggered release with enhanced foliar retention, improving efficacy while sparing honeybees and promoting rice growth, offering a promising resistance‐breaking strategy.
Chengshuai He +9 more
wiley +1 more source
Sex‐Specific Genetic Variants are Associated With Coronary Endothelial Dysfunction
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2016 BackgroundEndothelial dysfunction is an early stage of atherosclerosis. Single‐nucleotide polymorphisms (SNPs) have been associated with vascular dysfunction, cardiac events, and coronary artery remodeling.
Satoshi Yoshino +9 more
doaj +1 more source
Simultaneous Electrophysiology and Fiber Photometry in Freely Behaving Mice
Frontiers in Neuroscience, 2020 In vivo electrophysiology is the gold standard technique used to investigate sub-second neural dynamics in freely behaving animals. However, monitoring cell-type-specific population activity is not a trivial task.
Amisha A. Patel +3 more
doaj +1 more source
Advanced Science, EarlyView.ABSTRACT Diabetic stroke is characterized by a hyperglycemic and pro‐inflammatory microenvironment that exacerbates neurovascular dysfunction. However, the blood–brain barrier (BBB) remains a formidable obstacle, restricting the delivery of most therapeutic molecules.
Bixin Shen +7 more
wiley +1 more source
Pauses in cholinergic interneuron firing exert an inhibitory control on striatal output in vivo
eLife, 2018 The cholinergic interneurons (CINs) of the striatum are crucial for normal motor and behavioral functions of the basal ganglia. Striatal CINs exhibit tonic firing punctuated by distinct pauses.
Stefano Zucca +4 more
doaj +1 more source
Advanced Intelligent Discovery, EarlyView.Predictive models successfully screen nanoparticles for toxicity and cellular uptake. Yet, complex biological dynamics and sparse, nonstandardized data limit their accuracy. The field urgently needs integrated artificial intelligence/machine learning, systems biology, and open‐access data protocols to bridge the gap between materials science and safe ...
Mariya L. Ivanova +4 more
wiley +1 more source
Ciliomotor circuitry underlying whole-body coordination of ciliary activity in the Platynereis larva
eLife, 2017 Ciliated surfaces harbouring synchronously beating cilia can generate fluid flow or drive locomotion. In ciliary swimmers, ciliary beating, arrests, and changes in beat frequency are often coordinated across extended or discontinuous surfaces.
Csaba Verasztó +6 more
doaj +1 more source