Results 11 to 20 of about 436,718 (339)

Grape Seed Oil as a Natural Therapy in Male Rats with Alzheimer’s Diseases [PDF]

open access: yesAdvanced Pharmaceutical Bulletin, 2020
Purpose: Alzheimer’s disease (AD) is a chronic neurodegenerative disorder, with an increasing prevalence rate, mostly related to cholinergic system.
Farnoosh Berahmand   +3 more
doaj   +1 more source

An optimized acetylcholine sensor for monitoring in vivo cholinergic activity

open access: yesNature Methods, 2020
The ability to directly measure acetylcholine (ACh) release is an essential step toward understanding its physiological function. Here we optimized the GRABACh (GPCR-activation-based ACh) sensor to achieve substantially improved sensitivity in ACh ...
Miao Jing   +23 more
semanticscholar   +1 more source

Effects of different sugammadex doses on the train of four ratio recovery progression during rocuronium induced neuromuscular blockade in the rat phrenic nerve hemidiaphragm [PDF]

open access: yesKorean Journal of Anesthesiology, 2020
Background In this study, we used an ex-vivo model to investigate the recovery pattern of both the train-of-four (TOF) ratio and first twitch tension of TOF (T1), and determined their relationship during recovery from rocuronium-induced neuromuscular ...
Yong Beom Kim   +5 more
doaj   +1 more source

Muscarinic Acetylcholine Receptor Localization on Distinct Excitatory and Inhibitory Neurons Within the ACC and LPFC of the Rhesus Monkey

open access: yesFrontiers in Neural Circuits, 2022
Acetylcholine (ACh) can act on pre- and post-synaptic muscarinic receptors (mAChR) in the cortex to influence a myriad of cognitive processes. Two functionally-distinct regions of the prefrontal cortex—the lateral prefrontal cortex (LPFC) and the ...
Alexandra Tsolias   +2 more
doaj   +1 more source

Transient receptor potential canonical type 3 channels control the vascular contractility of mouse mesenteric arteries [PDF]

open access: yes, 2014
Transient receptor potential canonical type 3 (TRPC3) channels are non-selective cation channels and regulate intracellular Ca2+ concentration. We examined the role of TRPC3 channels in agonist-, membrane depolarization (high K+)-, and mechanical ...
Abramowitz, Joel   +6 more
core   +2 more sources

Cholinergic Projections From the Pedunculopontine Tegmental Nucleus Contact Excitatory and Inhibitory Neurons in the Inferior Colliculus

open access: yesFrontiers in Neural Circuits, 2020
The inferior colliculus processes nearly all ascending auditory information. Most collicular cells respond to sound, and for a majority of these cells, the responses can be modulated by acetylcholine (ACh). The cholinergic effects are varied and, for the
William A. Noftz   +5 more
doaj   +1 more source

Immunocytochemical Localization of Enzymes Involved in Dopamine, Serotonin, and Acetylcholine Synthesis in the Optic Neuropils and Neuroendocrine System of Eyestalks of Paralithodes camtschaticus

open access: yesFrontiers in Neuroanatomy, 2022
Identifying the neurotransmitters secreted by specific neurons in crustacean eyestalks is crucial to understanding their physiological roles. Here, we combined immunocytochemistry with confocal microscopy and identified the neurotransmitters dopamine (DA)
Elena Kotsyuba, Vyacheslav Dyachuk
doaj   +1 more source

Episodic memory: neurological and neuromediator mechanisms

open access: yesАнналы клинической и экспериментальной неврологии, 2017
Significant advances in understanding of neurological and neuromediatormechanisms of memory along with the causes ofmemory decline in aging were achieved recently.
A. G. Polunina, E. A. Bryun
doaj   +1 more source

An invertebrate-specific miRNA targeted the ancient cholinergic neuroendocrine system of oyster [PDF]

open access: yesOpen Biology, 2016
Acetylcholine (ACh) is the main neurotransmitter in the cholinergic neuroendocrine system and plays an indispensable role in modulating diverse immune responses.
Hao Chen   +6 more
doaj   +1 more source

Psychological stress induces an increase in cholinergic enteric neuromuscular pathways mediated by glucocorticoid receptors

open access: yesFrontiers in Neuroscience, 2023
IntroductionRepeated acute stress (RASt) is known to be associated with gastrointestinal dysfunctions. However, the mechanisms underlying these effects have not yet been fully understood.
Justine Blin   +13 more
doaj   +1 more source

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