Light‐Based Molecular Tools to Precisely Monitor and Operate β‐Adrenoceptors
Medicinal Research Reviews, EarlyView.ABSTRACT β‐Adrenoceptors are important G protein–coupled receptors involved in cardiovascular, metabolic, and neurological regulation. To study their function with high precision, light‐based molecular tools have been developed offering precise spatiotemporal control.
Ignazzitto Maria Tindara +3 more
wiley +1 more source
Correction: Sustaining Brain Youth by Neural Stem Cells: Physiological and Therapeutic Perspectives. [PDF]
Mol NeurobiolSantos M +3 more
europepmc +1 more source
Human Cyclophilins—An Emerging Class of Drug Targets
Medicinal Research Reviews, EarlyView.ABSTRACT Cyclophilins are a family of enzymes with peptidyl‐prolyl isomerase activity found in all cells of all organisms. To date, 17 cyclophilin isoforms have been identified in the human body, participating in diverse biological processes. Consequently, cyclophilins have emerged as promising targets for drug development to address a wide array of ...
Katarina Jurkova +3 more
wiley +1 more source
Comparative Analysis of Cholinergic Machinery in Carcinomas: Discovery of Membrane-Tethered ChAT as Evidence for Surface-Based ACh Synthesis in Neuroblastoma Cells. [PDF]
Int J Mol SciThakur B +4 more
europepmc +1 more source
Medicine Advances, EarlyView.FDA approval of IMAAVY (nipocalimab) marks a major advancement in the management of generalized myasthenia gravis (gMG). Clinical trial data showed significant improvements in MG‐ADL scores, especially in AChR‐positive patients, while also highlighting its favorable safety profile, potential for subcutaneous self‐administration, and greater ...
Muhammad Affan Abid +3 more
wiley +1 more source
Autonomic nervous system dysfunction in chronic obstructive pulmonary disease: mechanistic insights and therapeutic implications. [PDF]
Ann MedChen D, Zhou Z, Zhou Z, Zhao L, Chen Y.
europepmc +1 more source
Effect of Intracavernous Simultaneous Injection of Acetylcholine and VIP on Canine Penile Erection [PDF]
, 1992 Aboseif, Sherif R. +5 more
core
Neuronal Reshaping of the Tumor Microenvironment in Tumorigenesis and Metastasis: Bench to Clinic
Medicine Advances, EarlyView.This graphical abstract illustrates the multidimensional crosstalk between neurons and tumor microenvironment as well as targeted intervention strategies identified in the study. It highlights three core interaction axes: nerve‐tumor crosstalk mediated by neurotransmitters and neurotrophic factors, neuro‐vascular communication driving angiogenesis via ...
Yimao Wu +4 more
wiley +1 more source
An Integrated Engineering Approach to Creating Health‐Modulating Postbiotics
Molecular Nutrition &Food Research, EarlyView.Postbiotics have emerged as a promising alternative to live probiotics, offering comparable health benefits while overcoming challenges related to safety, stability, and shelf life. The review addresses current challenges in standardizing postbiotic definitions and production processes, and by outlining future research directions necessary to unlock ...
Michael Leonidas Chikindas +10 more
wiley +1 more source