Results 11 to 20 of about 128,683 (214)

Loss of Acetylcholine Signaling Reduces Cell Clearance Deficiencies in Caenorhabditis elegans. [PDF]

PLoS ONE, 2016
The ability to eliminate undesired cells by apoptosis is a key mechanism to maintain organismal health and homeostasis. Failure to clear apoptotic cells efficiently can cause autoimmune diseases in mammals.
Sérgio M Pinto, Johann Almendinger, Juan Cabello, Michael O Hengartner   +3 more
doaj   +1 more source

Anti-Kv1.4 Antibody Without Myasthenia Gravis

JACC: Case Reports, 2023
Anti-Kv1.4 antibody is often detected in thymoma-associated myasthenia gravis patients with anti-acetylcholine receptor antibody. Herein, we describe 2 patients with concurrent myocarditis and myositis.
Naoto Kuyama, MD, Seiji Takashio, MD, PhD, Takumi Nagakura, MD, Michie Imamura, MD, Koutaro Takamatsu, MD, PhD, Masafumi Takae, MD, PhD, Kyoko Hirakawa, MD, PhD, Kenshi Yamanaga, MD, PhD, Shinsuke Hanatani, MD, PhD, Eiichiro Yamamoto, MD, PhD, Kenichi Matsushita, MD, PhD, Mitsuharu Ueda, MD, PhD, Kenichi Tsujita, MD, PhD   +12 more
doaj   +1 more source

The role of muscarinic receptors in the beneficial effects of adenosine against myocardial reperfusion injury in rats. [PDF]

PLoS ONE, 2011
Adenosine, a catabolite of ATP, displays a wide variety of effects in the heart including regulation of cardiac response to myocardial ischemia and reperfusion injury.
Lei Sun, Dong-Ling Li, Mei Zhao, Xi He, Xiao-Jiang Yu, Yi Miao, Hao Wang, Jun Ren, Wei-Jin Zang   +8 more
doaj   +1 more source

Histological Protection by Donepezil Against Neurodegeneration Induced by Ischemia–Reperfusion in the Rat Retina

Journal of Pharmacological Sciences, 2010
Although a blockade of acetylcholine esterase has been reported to suppress neuronal cell death induced by exogenous glutamate and β-amyloid, information is still limited regarding the neuroprotective effects of the acetylcholine esterase inhibitor ...
Kenji Sakamoto, Kayo Ohki, Maki Saito, Tsutomu Nakahara, Kunio Ishii   +4 more
doaj   +1 more source

Autoimmune mechanisms elucidated through muscle acetylcholine receptor structures [PDF]

Cell
Minh C Pham, Jinfeng Teng, Kevin C O'Connor   +2 more
exaly   +2 more sources

Acetylcholine receptors [PDF]

Quarterly Reviews of Biophysics, 1974
The idea that certain drugs and neurotransmitters produce their effects by combining with specific receptors was first clearly expressed by Langley (1905) on the basis of the selective and localized effect of nicotine on striated muscle fibres. In 1914, Langley published a paper in which the antagonism between ‘curari’ and nicotine ...
openaire   +3 more sources

Case report: Immune remission from generalized myasthenia gravis in a dog with a thymoma and cholangiocellular carcinoma

Frontiers in Veterinary Science, 2023
A 9-year-old male neutered Cockapoo was presented with an acute and progressive history of exercise induced weakness involving all limbs, and bilateral decreased ability to blink.
Thomas Mignan, Thomas Mignan, Robert White, Kimberley Stee, Giuseppe Bonanno, Mike Targett, Mark Lowrie   +6 more
doaj   +1 more source

Acetylcholine receptor antagonists in acute respiratory distress syndrome: much more than muscle relaxants

Critical Care, 2018
Acetylcholine receptor antagonists have been shown to improve outcome in patients with severe acute respiratory distress syndrome. However, it is incompletely understood how these agents improve outcome.
Diana Jansen, Heder de Vries, Leo M. A. Heunks   +2 more
doaj   +1 more source

Correlation of anti-acetylcholine receptor antibody levels and long-term outcomes of juvenile myasthenia gravis in Taiwan: a case control study

BMC Neurology, 2019
Background Myasthenia gravis is the most common disease affecting the neuromuscular junction. The most common etiology among patients with juvenile myasthenia gravis is the production of antibodies against the acetylcholine receptor.
Cheng-Che Chou, I-Chen Su, I-Jun Chou, Jainn-Jim Lin, Shih-Yun Lan, Yi-Shan Wang, Shu-Sing Kong, Yun-Ju Chen, Meng-Ying Hsieh, Po-Cheng Hung, Huei-Shyong Wang, Min-Liang Chou, Kuang-Lin Lin, CHEESE study group   +13 more
doaj   +1 more source

Discoveries and future significance of research into amyloid-beta/α7-containing nicotinic acetylcholine receptor (nAChR) interactions

Pharmacological Research, 2023
Initiated by findings that Alzheimer’s disease is associated with a profound loss of cholinergic markers in human brain, decades of studies have examined the interactions between specific subtypes of nicotinic acetylcholine receptors and amyloid-β ...
Paul Whiteaker, Andrew A. George
doaj   +1 more source