Abstract Background Isolated rapid eye movement (REM) sleep behavior disorder (iRBD) is a prodromal manifestation of synucleinopathies and provides a critical window to identify early markers of progression to Parkinson's disease (PD) and dementia with Lewy bodies (DLB).
Lachlan Churchill+6 more
wiley +1 more source
Red blood cell endothelial nitric oxide synthase: A major player in regulating cardiovascular health
Abstract Red blood cells (RBCs) have traditionally been seen as simple carriers of gases and nutrients in the body. One important non‐canonical function of RBCs in the cardiovascular system is the regulation of nitric oxide (NO) metabolism. It has been shown that RBCs can scavenge NO, transport NO metabolites and produce NO in hypoxic conditions ...
Anthea LoBue+7 more
wiley +1 more source
Antifibrotic Effects of an α7 Nicotinic Acetylcholine Receptor Agonist in Keloid Fibroblasts and a Rat Scar Model. [PDF]
Roh H, Kim YH, Heo KJ, Hong JW, Lee WJ.
europepmc +1 more source
The physiological role of three acetylcholine receptors in synaptic transmission in Aplysia
Jacsue Kehoe
openalex +1 more source
Vagus Nerve Stimulation in Movement Disorders, from Principles to a Systematic Review of Evidence
Abstract Background The vagus nerve (VN), the principal component of the parasympathetic branch of the autonomic nervous system (ANS), mediates bidirec communication between the central nervous system (CNS) and peripheral organs. Vagus nerve stimulation (VNS), delivered through invasive (iVNS) or non‐invasive (transcutaneous cervical [tcVNS] and ...
Francesca Proietti+9 more
wiley +1 more source
Muscarinic acetylcholine receptor activated effectors in principal neurons of the rat basolateral amygdala. [PDF]
Sahagian TJ+4 more
europepmc +1 more source
Reaction of tetraethylammonium with the open and closed conformations of the acetylcholine receptor ionic channel complex. [PDF]
Michael Adler+4 more
openalex +1 more source
The “second‐hit” hypothesis proposes that both a genetic predisposition and an environmental insult—such as peripheral nerve trauma or spinal cord injury—are required for dystonia development. This review explores how neuroinflammation and maladaptive plasticity, triggered by nerve and spinal cord injury, contribute to dystonia pathogenesis.
Lisa Harder‐Rauschenberger+1 more
wiley +1 more source
Targeting Neuronal Alpha7 Nicotinic Acetylcholine Receptor Upregulation in Age-Related Neurological Disorders. [PDF]
Abraham SM, Suresh S, Komal P.
europepmc +1 more source