Results 181 to 190 of about 2,919,475 (397)
Hypotensive Episodes Precede Cognitive Fluctuations in Parkinson's Disease Dementia
Abstract Background Cognitive fluctuations (CFs) are a disabling feature in Parkinson's disease dementia (PDD) and contribute to caregiver burden. The relationship between CFs and neurogenic orthostatic hypotension (nOH), a common autonomic complication in PDD, has not been adequately examined.
Jorge Patino +6 more
wiley +1 more source
Direct anesthetic-like effects of forskolin on the nicotinic acetylcholine receptors of PC12 cells.
E M McHugh, Richard McGee
openalex +1 more source
Identification of N-terminal Extracellular Domain Determinants in Nicotinic Acetylcholine Receptor (nAChR) α6 Subunits That Influence Effects of Wild-type or Mutant β3 Subunits on Function of α6β2*- or α6β4*-nAChR [PDF]
Bhagirathi Dash +3 more
openalex +1 more source
M1 muscarinic acetylcholine receptor in Alzheimer’s disease
Shangtong Jiang +6 more
semanticscholar +1 more source
Abstract Background Non‐motor symptoms, especially autonomic dysfunction, are major contributors to disability and decreased quality of life in Parkinson's disease (PD). Despite being common and having a wide range of clinical facets, exocrine gland dysfunction is still not well recognized and managed.
Renato P. Munhoz +2 more
wiley +1 more source
Abstract Background The GBA1 gene encodes the lysosomal enzyme glucocerebrosidase (GCase). Parkinson's disease (PD) patients carrying a GBA1 variant (GBA‐PD) exhibit faster cognitive decline, linked to cholinergic degeneration. Objectives The aim was to investigate whether GCase activity, measured in monocytes, correlates with cognitive dysfunction or ...
Sofie Slingerland +8 more
wiley +1 more source

