Results 51 to 60 of about 128,683 (214)

Acetylcholine Attenuates Hydrogen Peroxide-Induced Intracellular Calcium Dyshomeostasis Through Both Muscarinic and Nicotinic Receptors in Cardiomyocytes

Cellular Physiology and Biochemistry, 2016
Background/Aims: Oxidative stress induced intracellular Ca2+ overload plays an important role in the pathophysiology of several heart diseases. Acetylcholine (ACh) has been shown to suppress reactive oxygen species generation during oxidative stress ...
Siripong Palee, Nattayaporn Apaijai, Krekwit Shinlapawittayatorn, Siriporn C. Chattipakorn, Nipon Chattipakorn   +4 more
doaj   +1 more source

Severe drug-induced repetitive behaviors and striatal overexpression of VAChT in ChAT-ChR2-EYFP BAC transgenic mice

Frontiers in Neural Circuits, 2014
In drug users, drug-related cues alone can induce dopamine release in the dorsal striatum. Instructive cues activate inputs to the striatum from both dopaminergic and cholinergic neurons, which are thought to work together to support motor learning and ...
Jill R Crittenden, Carolyn J Lacey, Tyrone eLee, Hilary A Bowden, Ann M Graybiel   +4 more
doaj   +1 more source

Toxic Effect of Cigarette Smoke on Brainstem Nicotinic Receptor Expression: Primary Cause of Sudden Unexplained Perinatal Death

Toxics, 2018
Among the neurotoxicants contained in tobacco smoke, if absorbed during pregnancy, nicotine significantly affects α7-nicotinic acetylcholine receptors, which play essential roles in the development of the brainstem regions receiving cholinergic ...
Anna Maria Lavezzi
doaj   +1 more source

On the localization of acetylcholine receptors [PDF]

The Journal of Physiology, 1955
J, DEL CASTILLO, B, KATZ
openaire   +2 more sources

Pathogenesis of Cholinergic Urticaria in Relation to Sweating

Allergology International, 2012
Cholinergic urticaria (CU) has clinically characteristic features, and has been frequently described in the literature. However, despite its comparatively old history, the pathogenesis and classification remains to be clarified.
Toshinori Bito, Yu Sawada, Yoshiki Tokura   +2 more
doaj   +1 more source

A Bead-Based Nonradioactive Immunoassay for Autoantibody Testing in a Mouse Model of Myasthenia Gravis

Antibodies
Serological testing for anti-acetylcholine receptor (AChR) autoantibodies is not only crucial for the diagnosing, disease monitoring, and treatment management of patients with myasthenia gravis (MG) but also for preclinical studies utilizing MG disease ...
Afrin Bahauddin, Kyra Curtis, Jutatip Guptarak, Ruksana Huda   +3 more
doaj   +1 more source

Block by Phytoestrogens of Recombinant Human Neuronal Nicotinic Receptors

Journal of Pharmacological Sciences, 2003
: The effects of phytoestrogens on neuronal nicotinic acetylcholine receptor/channels were examined by expressing recombinant channels in Xenopus oocytes.
Ken Nakazawa, Yasuo Ohno
doaj   +1 more source

Teaching an Old Drug New Tricks: Agonism, Antagonism, and Biased Signaling of Pilocarpine through M3 Muscarinic Acetylcholine Receptor [PDF]

, 2017
Alexey Pronin, Qiang Wang, Vladlen Z. Slepak   +2 more
openalex   +1 more source

Allosteric Agonism of α7 Nicotinic Acetylcholine Receptors: Receptor Modulation Outside the Orthosteric Site [PDF]

, 2019
Alican Gulsevin, Roger L. Papke, Clare Stokes, Sumanta Garai, Ganesh A. Thakur, Marta Quadri, Nicole A. Horenstein   +6 more
openalex   +1 more source

Barbiturate Action Is Dependent on the Conformational State of the Acetylcholine Receptor [PDF]

, 1993
Alberto J. de Armendi, Peter H. Tonner, Birgitte Bugge, Keith Miller   +3 more
openalex   +1 more source