Results 71 to 80 of about 116,451 (242)

Pathogenesis of Cholinergic Urticaria in Relation to Sweating

Allergology International, 2012
Cholinergic urticaria (CU) has clinically characteristic features, and has been frequently described in the literature. However, despite its comparatively old history, the pathogenesis and classification remains to be clarified.
Toshinori Bito, Yu Sawada, Yoshiki Tokura   +2 more
doaj   +1 more source

A Bead-Based Nonradioactive Immunoassay for Autoantibody Testing in a Mouse Model of Myasthenia Gravis

Antibodies
Serological testing for anti-acetylcholine receptor (AChR) autoantibodies is not only crucial for the diagnosing, disease monitoring, and treatment management of patients with myasthenia gravis (MG) but also for preclinical studies utilizing MG disease ...
Afrin Bahauddin, Kyra Curtis, Jutatip Guptarak, Ruksana Huda   +3 more
doaj   +1 more source

Similarity of effects of oxygen, sulfur, and selenium isologs on the acetylcholine receptor in excitable membranes of junctions and axons. [PDF]

, 1966
P. Rosenberg, Henry G. Mautner, David Nachmansohn   +2 more
openalex   +1 more source

Monod-Wyman-Changeux Analysis of Ligand-Gated Ion Channel Mutants [PDF]

arXiv, 2017
We present a framework for computing the gating properties of ligand-gated ion channel mutants using the Monod-Wyman-Changeux (MWC) model of allostery. We derive simple analytic formulas for key functional properties such as the leakiness, dynamic range, half-maximal effective concentration, and effective Hill coefficient, and explore the full spectrum
arxiv  

A case report of nivolumab-induced myasthenia gravis and myositis in a metastatic renal cell carcinoma patient

Urology Case Reports, 2020
We present a 78-year-old male with renal cell carcinoma who developed myasthenia gravis complicated by myositis after nivolumab administration, which was verified by the presence of antibodies against the acetylcholine receptor.
Shotaro Nakanishi, Sho Nishida, Minoru Miyazato, Masato Goya, Seiichi Saito   +4 more
doaj  

Beneficial effects of anisodamine in shock involved nicotinic anti-inflammatory pathway

Frontiers in Pharmacology, 2011
Anisodamine, an antagonist of muscarinic receptor, has been used therapeutically to improve blood flow in circulatory disorders such as septic shock in China since 1965.
Ting eZhao, Dong-Jie eLi, Chong eLiu, Ding-Feng eSu, Fu-Ming eShen   +4 more
doaj   +1 more source

Impaired neurovascular coupling in the APPxPS1 mouse model of Alzheimer’s disease [PDF]

arXiv, 2019
The tight coupling between neuronal activity and the local increase of blood flow termed neurovascular coupling is essential for normal brain function. This mechanism of regulation is compromised in Alzheimer's Disease (AD). In order to determine whether a purely vascular dysfunction or a neuronal alteration of blood vessels diameter control could be ...
arxiv  

On Some Structural Analogies between Acetylcholinesterase and the Macromolecular Receptor of Acetylcholine [PDF]

, 1969
Jean‐Pierre Changeux, Thomas R. Podleski, Jean‐Claude Meunier   +2 more
openalex   +1 more source

Effects of Selective Estrogen Receptor Modulators on Plasma Membrane Estrogen Receptors and Catecholamine Synthesis and Secretion in Cultured Bovine Adrenal Medullary Cells

Journal of Pharmacological Sciences, 2014
.: We previously reported the occurrence and function of plasma membrane estrogen receptors in cultured bovine adrenal medullary cells. Here we report the effects of raloxifene and tamoxifen, selective estrogen receptor modulators, on plasma membrane ...
Hirohide Inagaki, Yumiko Toyohira, Keita Takahashi, Susumu Ueno, Go Obara, Toshinori Kawagoe, Masato Tsutsui, Toru Hachisuga, Nobuyuki Yanagihara   +8 more
doaj  

Erratum to: Effect of Acetylcholine on the Cardiovascular and Respiratory System in Different Experimental Preparations (and the Role of Baro-Receptors) [PDF]

, 1960
S. R. Mukherjee, J. Mitra, B. N. Koley
openalex   +1 more source