Results 281 to 290 of about 137,412 (311)
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Canadian Journal of Biochemistry, 1964
The general characteristics of acetylcholinesterase are described. The mechanism of action of the enzyme is considered primarily in relation to the two steps in the hydrolysis of acetylcholine, the acetylation and deacetylation reactions. Competitive and non-competitive inhibition, and inhibitions by hydrogen ion and by substrate, are explained in ...
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The general characteristics of acetylcholinesterase are described. The mechanism of action of the enzyme is considered primarily in relation to the two steps in the hydrolysis of acetylcholine, the acetylation and deacetylation reactions. Competitive and non-competitive inhibition, and inhibitions by hydrogen ion and by substrate, are explained in ...
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Tetrahydrocannabinol and acetylcholinesterase
Pharmacology Biochemistry and Behavior, 1978Recent evidence suggests that the psychoactive effect of delta-9-tetrahydrocannabinol (delta9-THC), the major psychoactive constituent of marihuana, may be mediated through an alteration of cholinergic neurotransmission. One possible mechanism by which delta9-THC could have its effect is by affecting acetylcholinesterase (AChE) and there is evidence ...
D E, Moss, P L, Peck, R, Salome
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Plasma acetylcholinesterase activity
American Journal of Obstetrics and Gynecology, 1950Abstract ChE activity in plasma from normal adult nonmenstruating, nonpregnant women, from women during normal pregnancy, and from patients with toxemia of pregnancy was determined manometrically. Significant differences were observed among the three groups. This difference was independent of medication (Sodium Amytal), and could not be attributed to
W W, TOURTELLOTTE, L D, ODELL
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Molecular Dynamics of Acetylcholinesterase
Accounts of Chemical Research, 2002Molecular dynamics simulations are leading to a deeper understanding of the activity of the enzyme acetylcholinesterase. Simulations have shown how breathing motions in the enzyme facilitate the displacement of substrate from the surface of the enzyme to the buried active site.
Shen, Tongye +3 more
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Toward an Artificial Acetylcholinesterase
Chemistry - A European Journal, 2000The methanolysis of choline p-nitrophenylcarbonate in chloroform containing 1% methanol is catalyzed with turnover by ditopic receptors 1 and 2, consisting of a calix[6]arene connected to a bicyclic guanidinium by means of a short spacer. The calix[6]arene subunit strongly binds to the trimethylammonium head group through cation-pi interactions ...
CUEVAS F. +5 more
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Progress in clinical and biological research, 1976
S H, Sandifer, J E, Kiel, B C, Strever
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S H, Sandifer, J E, Kiel, B C, Strever
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