Results 261 to 270 of about 176,476 (335)
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Biophysics of Structure and Mechanism, 1980
Three mechanisms have been suggested to describe the inhibition of acetylcholinesterase (EC. 3.1.1.7) by an excess of acetylcholine. (i) Substrate inhibition occurs through the reaction of acetylcholine with acetylated enzyme. The deacetylation of this ternary complex is supposed to be completely inhibited.
P, Hofer, U P, Fringeli
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Three mechanisms have been suggested to describe the inhibition of acetylcholinesterase (EC. 3.1.1.7) by an excess of acetylcholine. (i) Substrate inhibition occurs through the reaction of acetylcholine with acetylated enzyme. The deacetylation of this ternary complex is supposed to be completely inhibited.
P, Hofer, U P, Fringeli
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Journal of Molecular Structure, 2020
Ten hydrazone derivatives bearing a (benz)imidazole nucleus were designed, synthesized and evaluated for their antioxidant, antifungal, and anti-acetylcholinesterase activities.
Imène Amine Khodja +3 more
semanticscholar +1 more source
Ten hydrazone derivatives bearing a (benz)imidazole nucleus were designed, synthesized and evaluated for their antioxidant, antifungal, and anti-acetylcholinesterase activities.
Imène Amine Khodja +3 more
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Bioorganic chemistry (Print), 2019
A novel class of fluoro-substituted tris-chalcones derivatives (5a-5i) was synthesized from phloroglucinol and corresponding benzaldehydes. A three step synthesis method was followed for the production of these tris-chalcone compounds.
Serdar Burmaoglu +5 more
semanticscholar +1 more source
A novel class of fluoro-substituted tris-chalcones derivatives (5a-5i) was synthesized from phloroglucinol and corresponding benzaldehydes. A three step synthesis method was followed for the production of these tris-chalcone compounds.
Serdar Burmaoglu +5 more
semanticscholar +1 more source
Target Enzyme in Alzheimer's Disease: Acetylcholinesterase Inhibitors.
Current Topics in Medicinal Chemistry, 2019Alzheimer's Disease (AD), affecting a large population worldwide is characterized by the loss of memory and learning ability in the old population. The enzyme Acetylcholinesterase Enzyme (AChE) is the key enzyme in the hydrolysis of the neurotransmitter ...
M. Saxena, R. Dubey
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Breathing Without Acetylcholinesterase
2004Acetylcholine (ACh) mediates neurotransmission at the neuromuscular junction and is involved in respiratory control1, notably chemosensitivity2 of central and peripheral origin. The level of ACh at the synaptic cleft and neuromuscular junction is regulated by the enzyme acetylcholinesterase (AChE).
Chatonnet, Fabrice +4 more
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Trends in Food Science & Technology, 2019
Background Organophosphate pesticides have been extensively used to protect the agricultural produce from being damaged by the pests while growing and the subsequent degradation in its quality.
Hitika B. Patel +2 more
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Background Organophosphate pesticides have been extensively used to protect the agricultural produce from being damaged by the pests while growing and the subsequent degradation in its quality.
Hitika B. Patel +2 more
semanticscholar +1 more source
Canadian Journal of Biochemistry, 1964
The general characteristics of acetylcholinesterase are described. The mechanism of action of the enzyme is considered primarily in relation to the two steps in the hydrolysis of acetylcholine, the acetylation and deacetylation reactions. Competitive and non-competitive inhibition, and inhibitions by hydrogen ion and by substrate, are explained in ...
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The general characteristics of acetylcholinesterase are described. The mechanism of action of the enzyme is considered primarily in relation to the two steps in the hydrolysis of acetylcholine, the acetylation and deacetylation reactions. Competitive and non-competitive inhibition, and inhibitions by hydrogen ion and by substrate, are explained in ...
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Triclosan alters adult zebrafish behavior and targets acetylcholinesterase activity and expression.
Environmental Toxicology and Pharmacology, 2019Triclosan is widely used in consumer products as an antimicrobial agent. Epidemiological studies have reported the association of triclosan with adverse birth outcomes.
Narasimha Pullaguri +3 more
semanticscholar +1 more source
Acta Physiologica, 2019
Cardiovascular diseases remain a major cause of morbidity and mortality worldwide. Cardiovascular diseases such as acute myocardial infarction, ischaemia/reperfusion injury and heart failure are associated with cardiac autonomic imbalance characterized ...
T. Khuanjing +3 more
semanticscholar +1 more source
Cardiovascular diseases remain a major cause of morbidity and mortality worldwide. Cardiovascular diseases such as acute myocardial infarction, ischaemia/reperfusion injury and heart failure are associated with cardiac autonomic imbalance characterized ...
T. Khuanjing +3 more
semanticscholar +1 more source