Journal of Neurochemistry, Volume 170, Issue 6, June 2026.Brain cholesterol homeostasis is tightly regulated and largely independent of peripheral cholesterol. This review proposes a unifying framework in which aging, sex, and related biological stressors, including hypercholesterolemia, neurodegeneration, inflammation, and oxidative stress, converge to disrupt cholesterol homeostasis in the brain ...
Myuri Ruthirakuhan +2 more
wiley +1 more source
Effects of acetylcysteine combined with bronchoalveolar lavage under fiberoptic bronchoscopy on blood oxygenation and inflammation in elderly severe pneumonia patients. [PDF]
Am J Transl ResWu Y, Yao J, Zhang Y.
europepmc +1 more source
Redox Disruption Induced by Saquayamycin B1 Promotes Cytotoxicity in Resistant Melanoma Cells
ChemMedChem, Volume 21, Issue 10, 27 May 2026.Saquayamycin B1 (SQ‐B1), an antibiotic isolated from Streptomyces sp. I072, triggers cell death in different melanoma cell lines, including chemoresistant SK‐MEL‐5. SQ‐B1 elevates O2•‐ and NO• on both sides of the membrane and blocks glutathione transferase (GSTP‐1) and glutathione reductase (GSR), destabilizing the GSH/GSSG antioxidant system.
Geovana Guedes Silvestre +13 more
wiley +1 more source
Severe Hepatocellular Injury With Transaminases > 20,000 IU/L in Suspected Repeated Drug Ingestion Despite Undetectable Serum Levels. [PDF]
CureusPatel V, Khan RS, Rangasamy A, Shah R.
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Correction to "<i>N</i>-Acetylcysteine Reduces ROS-Mediated Oxidative DNA Damage and PI3K/Akt Pathway Activation Induced by <i>Helicobacter pylori</i> Infection". [PDF]
Oxid Med Cell Longeveuropepmc +1 more source
Administration of N-acetylcysteine influence the expression of apoptotic genes in the granulosa cells of infertile women diagnosed with endometriosis. [PDF]
Sci RepHeshmati ZS +7 more
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Cytoprotective Effects of Lipid Emulsion Against Bupivacaine-Induced Cytotoxicity in Human Rotator Cuff Fibroblasts. [PDF]
Antioxidants (Basel)Kim RJ, Park HB.
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High sucralose exposure in early pregnancy increases the susceptibility of heart defects in mice offspring. [PDF]
iScienceZhang Z +7 more
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Clinical characteristics and outcomes of pediatric paracetamol poisoning presenting to the emergency department. [PDF]
BMC PediatrKarabacak B, Özaydın E.
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Spectrum of Hepatic Manifestation in Neonatal Dengue: A Case Report. [PDF]
Sage Open PediatrChrisbina JA, Krishnan BA.
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