Results 181 to 190 of about 45,061 (213)

Abstracts from the 2026 Congress of the Scandinavian Society of Anesthesiology and Intensive Care Medicine, Reykjavik, Iceland, June 10–12, 2026

Acta Anaesthesiologica Scandinavica, Volume 70, Issue 9, October 2026.
wiley   +1 more source

Targeting eIF5A combats breast cancer progression by ClpP‐dependent mitochondrial oxidative stress

Interdisciplinary Medicine, Volume 4, Issue 5, September 2026.
This study identified the eIF5A‐ClpP axis as a key driver of breast cancer progression. Targeting eIF5A suppresses tumor growth by inducing ClpP‐dependent mitochondrial oxidative stress, revealing a novel therapeutic vulnerability. Abstract Breast cancer (BC) poses a persistent global health challenge, necessitating new therapeutic targets.
Jinmei Zhu, Baoyuan Tang, Bei Xie, Haohua Deng, Haitang Yang, Lei Ma, Ziqing Zhang, Yicheng Ma, Xingyuan Ma, Shuaiyang Wang, Jing Li, Lei Zhao, Wengui Shi, Linjing Li   +13 more
wiley   +1 more source

A comparative study of the impact of prescription and non-prescription mucolytic agents on respiratory disease management in a community-based population. [PDF]

Front Pharmacol
Dawane JS, Mehetre KN, Shinde J.
europepmc   +1 more source

FAM107A loss facilitates TTK‐OPTN‐mediated mitophagy to drive docetaxel resistance in castration‐resistant prostate cancer

Interdisciplinary Medicine, Volume 4, Issue 5, September 2026.
In the progression of docetaxel resistance, downregulation of FAM107A releases its transcriptional repression of TTK, leading to TTK upregulation. TTK enhances the interaction and phosphorylation of OPTN. This activates mitophagy in tumor cells, facilitates clearance of damaged mitochondria, reduces intracellular reactive oxygen species accumulation ...
Yishan Zhang, Fan Zou, Mingdong Wang, Chenyue Wu, Yingwei Xie, Yongjun Quan, Wei Yan, Yupeng Zheng, Lianhua Li, Yuexin Liu, Jian Yu, Hao Ping   +11 more
wiley   +1 more source

Efficacy and safety of N-acetylcysteine in patients with mild cognitive impairment undergoing exercise-based cardiac rehabilitation program: a randomized controlled trial. [PDF]

Alzheimers Res Ther
Gallagher D, Kang Y, Herrmann N, Kiss A, Black SE, Oh P, Marzolini S, Rabin JS, Andreazza A, Ramirez J, Gao F, Rapoport M, Chen JJ, Survilla K, Vieira D, Mah E, Swardfager W, Lanctôt KL.   +17 more
europepmc   +1 more source

Morphological and Biochemical Insights Into the Renoprotective Effects of Combined N-Acetylcysteine and Glycine Treatment in Experimental Diabetic Nephropathy. [PDF]

Pharmacol Res Perspect
Ejubović M, Belančić A, Lam YW, Javid F, Kapić D, Ćosović E, Jahić R, Lepara O, Ejubović AJ, Alić L, Topuz A, Ajanović Z, Fajkić A.   +12 more
europepmc   +1 more source

N-acetylcysteine alleviates experimental autoimmune prostatitis in rats by activating PI3K/Akt/CREB and Keap1/Nrf2 pathways. [PDF]

Transl Androl Urol
Wu C, Fu F, Xiong Y, Qin F, Liu Y, Yuan J.   +5 more
europepmc   +1 more source

Uncertain timing of reported acetaminophen ingestion in an adolescent analgesic overdose: a case report. [PDF]

Front Pediatr
Alghamdi WA.
europepmc   +1 more source

The Efficacy of N-acetylcysteine as an Adjunct in the Management of Acute Zinc Phosphide Poisoning: A Randomized Double-Blind Controlled Trial. [PDF]

Cureus
V SK, Nagal JB, Meena K, Jain K.
europepmc   +1 more source

Unraveling the complex role of intestinal microbiota in drug permeability: Insights from N-acetylcysteine. [PDF]

Asian J Pharm Sci
Tian C, He Z.
europepmc   +1 more source