Results 261 to 270 of about 88,160 (292)

Anti‐Tubercular Drug‐Induced Liver Injury: Current Understanding and Emerging Directions

JGH Open, Volume 10, Issue 1, January 2026.
ABSTRACT Most common adverse effect causing cessation of anti‐tubercular treatment (ATT) is drug‐induced liver injury (DILI) which is unpredictable due to its idiosyncratic nature. ATT is the most common cause of DILI and drug‐induced acute liver failure (ALF) in South East Asia.
Shubham Prasad, Himanshu Narang, Saurabh Kedia, Vineet Ahuja   +3 more
wiley   +1 more source

CDG due to Defective Membrane Transporters: Update

Journal of Inherited Metabolic Disease, Volume 49, Issue 1, January 2026.
ABSTRACT Congenital disorders of glycosylation are genetic defects in the glycoprotein and glycolipid glycan assembly and attachment. Some 200 CDG have been reported since the first clinical description in 1980. Most CDG are enzymatic deficiencies, but 13 (6.5%) are defects in the ER, Golgi apparatus (GA), and plasma membrane transporters.
D. Quelhas, C. R. Ferreira, J. Jaeken
wiley   +1 more source

February 2026 global research highlights

Hong Kong Journal of Emergency Medicine, Volume 33, Issue 1, February 2026.
wiley   +1 more source

Retrospective Case Series of Fulminant Metabolic Crisis in GSDIA: Persistent Lactic Acidosis Despite Correction of Hypoglycemia May Reflect Secondary Mitochondrial Dysfunction

JIMD Reports, Volume 67, Issue 1, January 2026.
ABSTRACT Although several advances in glycogen storage disorder (GSD) management have been made over the years, there is still increased morbidity and mortality in these patients, particularly among those with GSD type I (GSDI). Here, we describe a case series of five patients with GSDIa who presented with severe lactic acidosis and passed away without
Herodes Guzman, Nicole Stewart, Lauren Mitteer, Victoria Sanders, Rebecca Ganetzky, Diva D. De Leon   +5 more
wiley   +1 more source

Management of paraquat poisoning in an adolescent with progressive acute kidney injury: a case report. [PDF]

Ann Med Surg (Lond)
Karn V, Shrestha B, Shrestha R, Thapa SB, Gyawali P, Sharma AK.   +5 more
europepmc   +1 more source

Oral Melatonin in Critically Ill Patients With COVID‐19: A Quasi‐Experimental Pragmatic Trial

Journal of Medical Virology, Volume 98, Issue 1, January 2026.
ABSTRACT Melatonin has demonstrated antioxidant, anti‐inflammatory, and potential antiviral properties. Its therapeutic role in critically ill COVID‐19 patients admitted to intensive care was underexplored at the start of the pandemic. We conducted a quasi‐experimental, pragmatic study over 4 consecutive uninterrupted time periods alternating control ...
Miguel Sánchez‐García, Jesús A.F. Tresguerres, Manuel Álvarez‐González, Belén de la Hera, Virginia Puebla, Lidia Ybañez, José‐Manuel Martínez‐Sesmero, Antonio Blesa, Juan‐Carlos Martín‐Benítez, Fernando Martínez‐Sagasti, Paloma González‐Arenas, Sara Domingo, Cándido Pardo, Silmary Maichle, Carolina Postigo, Sara De‐Miguel, María Bringas, Raquel González‐Casanova, Viktor Yordanov, Alberto Delgado‐Iribarren, Esther Culebras, Miguel A. Armengol‐de la‐Hoz, Antonio Núñez‐Reiz   +22 more
wiley   +1 more source

The potential treatment of N-acetylcysteine as an antioxidant in the radiation-induced heart disease

Yanling Li, Gang Wang, Bowen Wang, Yonghong Li, Y. Ma, Yuan Huang, Wen-Ting Yan, Ping Xie   +7 more
openalex   +1 more source

Mastering Organoid Growth: A Complete Guide to Overcoming Methodological Challenges

MedComm, Volume 7, Issue 1, January 2026.
Organoids offer transformative 3D models that precisely mimic human organ architecture and function. This review details the latest methodology, emphasizing the cultivation of liver and other abdominal organoids. We analyze technological challenges (e.g., nutrient delivery, scalability, diversity) and provide practical insights for new researchers ...
Chunbao Jiao, Omer Faruk Karakaya, Neda Dadgar, Chase J. Wehrle, Zahra Massoud, Hanna Hong, Robert L. Fairchild, Nic Leipzig, Federico Aucejo, Wen Wee Ma, Jan Joseph Melenhorst, Sofia Ferreira Gonzales, Andrea Schlegel   +12 more
wiley   +1 more source

Enemas with sucralfate and n-acetylcysteine can reduce inflammation and oxidative stress in colonic mucosa without fecal stream. [PDF]

Acta Cir Bras
Zanesco MC, Yoshitani MM, Fagundes FL, Campos FG, Pereira PP, Pereira QC, Pereira JA, Santos RC, Martinez CAR.   +8 more
europepmc   +1 more source