Results 271 to 280 of about 88,160 (292)

Evaluation of the Safety and Efficacy of N-acetylcysteine in the Prevention of Paclitaxel-induced Peripheral Neuropathy: A Randomized, Double-blind, and Placebo-controlled Trial

Sima Ramezaninejad, Ehsan Zaboli, Mohammad Eslamijouybari, Leila Mirzakhani, Fatemeh Shaki, Mahmood Moosazadeh, Hamid Reza Namvar, Amir Mohammad Shabani, Ebrahim Salehifar   +8 more
openalex   +1 more source

Effect of Glucoraphanin on the Abundance of Nrf2 Regulated Genes Within Circulating Small Extracellular Vesicles: A Pilot Dietary Intervention

Molecular Nutrition &Food Research, Volume 70, Issue 2, 29 January 2026.
Broccoli accumulates glucoraphanin, converted to sulforaphane, which activates nuclear factor erythroid 2‐related factor 2 (Nrf2), which may reduce age‐related inflammation. Given sulforaphane's rapid excretion, we hypothesised that its effects are mediated via plasma extracellular vesicles (EVs).
Nishantika Mitra, Mark H. Vickers, Fiona E. Lithander, Anastasiia Artuyants, Cherie Blenkiron, Meika Foster, Hui Hui Phua, Chris Pook, Zeke Wang, Richard F. Mithen, Farha Ramzan   +10 more
wiley   +1 more source

Refractory high anion gap metabolic acidosis due to chronic paracetamol use: a case report. [PDF]

J Med Case Rep
Lamabadusuriya DA, Bopitiya AK, Perera ADNW, Munasinghe J, Govindapala BGDS, Jayasekera MMPT.   +5 more
europepmc   +1 more source

Development and Characterization of Copaiba Oil‐Loaded Polymeric Nanocapsules With Enhanced Antitumor Activity Against Breast Cancer Cells

Particle &Particle Systems Characterization, Volume 43, Issue 1, January 2026.
The present study developed and characterized a novel copaiba oil polymeric nanoparticle (NPOC), which was efficiently internalized by breast cancer cells, exhibited greater cytotoxicity and selectivity than free copaiba oil and standard drug doxorubicin. NPOC also reduced tumor growth and migration in 3D models.
Karinne Kelly Gadelha Marques, Allesya Lara Dantas Formiga, Ramon Ramos Marques de Souza, Isione Oliveira Castro, Heivila Monique da Silva Alexandre, Igor Gabriel da Silva Ramalho, Érika Raisla Melquiades Pereira, Lucas Medeiros Martins Carvalho, Marianna Vieira Sobral, Francisco Humberto Xavier Júnior, Juan Carlos Ramos Gonçalves   +10 more
wiley   +1 more source

DPMAS in the Management of Severe Acute Liver Injury. [PDF]

Case Reports Hepatol
Tavera Díaz MA, Aguilar Loayza A, Mejía Vargas CB, Mamani Ochoa JF.   +3 more
europepmc   +1 more source

The possibilities of N-acetylcysteine in the complex therapy of chronic obstructive pulmonary disease

Е. В. Болотова, T. I. Frolova
openalex   +2 more sources

Chondrocyte‐Targeted Nanoparticles Loaded with N‐Acetylcysteine Protect Articular Cartilage and Attenuate Osteoarthritis by Inhibiting Ferroptosis via Glutathione Maintenance

Small Science, Volume 6, Issue 1, January 2026.
Chondrocyte‐targeted CS‐NAC nanoparticles restore redox balance, inhibit ferroptosis, and protect cartilage under mechanical stress. This nanoplatform enhances joint retention, elevates GPX4 activity, and attenuates osteoarthritis progression, offering a promising disease‐modifying therapeutic strategy.
Shaoyi Wang, Fujian Zhang, Xiaocong Zhou, Jie Yang, Zhe Li, Songlin Li, Qunshan Lu, Houyi Sun, Peilai Liu   +8 more
wiley   +1 more source

Add-On Pharmacotherapy in Schizophrenia: Does It Improve Long-Term Outcomes? A Systematic Review. [PDF]

J Clin Med
Smyrnis A, Smyrnis G, Smyrnis N.
europepmc   +1 more source

Macropinocytic Uptake and pH‐Responsive Endolysosomal Processing Drive Sustained Chemotherapeutic Efficacy of High‐Load Core@Shell Nanocarriers in Colorectal Cancer

Small Science, Volume 6, Issue 1, January 2026.
This study develops core@shell nanocarriers with an exceptionally high chemotherapy drug payload, exhibiting strong cytotoxic effects. Using this adaptable nanocarrier‐synthesis platform, herein, the cellular uptake pathway and intracellular journey of the nanocarriers are elucidated with different probe‐based imaging strategies.
Dolma Choezom, Silke Notter, Titus Griebel, Nathalia Ferreira, Johann Gruetz, Ajinkya Kulkarni, Matthias Schröter, Gražvydas Lukinavičius, Wiebke Möbius, Lena‐Christin Conradi, Claus Feldmann, Frauke Alves   +11 more
wiley   +1 more source

Modulation of lncRNAs and oxidative stress related genes by N-acetylcysteine and S-methylcysteine in rotenone-induced Parkinson's disease. [PDF]

Biochem Biophys Rep
Yaqubi S, Seyedalipour B, Karimian M.
europepmc   +1 more source