Results 21 to 30 of about 88,160 (292)

Prevention of acute kidney injury and protection of renal function in the intensive care unit : update 2017 [PDF]

open access: yes, 2017
Background: Acute kidney injury (AKI) in the intensive care unit is associated with significant mortality and morbidity. Objectives: To determine and update previous recommendations for the prevention of AKI, specifically the role of fluids, diuretics ...
Druml, W   +8 more
core   +3 more sources

IMPACT OF SEVOFLURANE AND ACETYLCYSTEINE ON ISCHEMIA-REPERFUSION INJURY OF THE LIVER FROM BRAIN-DEAD DONOR

open access: yesВестник трансплантологии и искусственных органов, 2013
Aim. The purpose of our work was to estimate the impact of preconditioning with acetylcysteine and sevoflurane on ischemia-reperfusion injury of cadaveric donor liver with marginal features. Methods and results.
A. E. Shcherba   +6 more
doaj   +1 more source

Effect of N-acetyl-L-cysteine on Testicular Tissue in Busulfan-Induced Dysfunction in the Male Reproductive System

open access: yesThe World Journal of Men's Health, 2023
Purpose: This study aimed to evaluate the protective effect of N-acetyl-L-cysteine (NAC) as an antioxidant on busulfaninduced testicular dysfunction in mice and elucidate its possible mechanism of action.
Kyung Hwan Kim   +3 more
doaj   +1 more source

Chromon-3-aldehyde derivatives restore mitochondrial function in rat cerebral ischemia [PDF]

open access: yesIranian Journal of Basic Medical Sciences, 2020
Objective(s): This work aimed to assess the effect of 10 new chromon-3-aldehyde derivatives on changes of mitochondrial function under the conditions of brain ischemia in rats.
Dmitry Pozdnyakov   +2 more
doaj   +1 more source

Pirfenidone treatment in idiopathic pulmonary fibrosis: A Saudi experience

open access: yesAnnals of Thoracic Medicine, 2015
Background: Recent trials involving pirfenidone suggest a beneficial effect in the treatment of idiopathic pulmonary fibrosis (IPF). Objective: To report on the efficacy and safety of pirfenidone in the treatment of patients with IPF, at a tertiary care
Esam H Alhamad
doaj   +1 more source

Protective Effect of N-Acetyl Cysteine on Chlorpyrifos-Induced Testicular Toxicity in Mice [PDF]

open access: yesInternational Journal of Fertility and Sterility, 2019
Background Chlorpyrifos (CPF), an organophosphate pesticide, is widely used in farms in order to preserve crops and fruits. Previous studies have shown that CPF exposure might cause chronic toxicity in male genital system.
Rasoul Kheradmandi   +4 more
doaj   +1 more source

The Potential Use of Metformin, Dipyridamole, N-Acetylcysteine and Statins as Adjunctive Therapy for Systemic Lupus Erythematosus

open access: yesCells, 2019
Systemic lupus erythematosus (SLE) is a chronic inflammatory autoimmune condition that can potentially affect every single organ during the course of the disease, leading to increased morbidity and mortality, and reduced health-related quality of life ...
Marcus Kai Xuan Tan   +2 more
doaj   +1 more source

Metagenomic Sequencing Analysis of the Effects of Acetylcysteine on the Pig Gut Microbiome

open access: yesMicrobiology Research, 2023
The gut microbiota is engaged in multiple interactions affecting host health, and gut dysbiosis can lead to many diseases. However, the effects of acetylcysteine (NAC) on the gut microbiome composition in pigs using metagenomic sequencing have not been ...
Shulin Fu   +10 more
doaj   +1 more source

Dimethyl Fumarate Alleviates Dextran Sulfate Sodium-Induced Colitis, through the Activation of Nrf2-Mediated Antioxidant and Anti-inflammatory Pathways. [PDF]

open access: yes, 2020
Oxidative stress and chronic inflammation play critical roles in the pathogenesis of ulcerative colitis (UC) and inflammatory bowel diseases (IBD). A previous study has demonstrated that dimethyl fumarate (DMF) protects mice from dextran sulfate sodium ...
Farzaneh, Ted   +8 more
core   +2 more sources

Glutathione treatment protects the rat liver against injury after warm ischemia and Kupffer cell activation [PDF]

open access: yes, 2002
Background/Aim: The generation of reactive oxygen species by activated Kupffer cells (KC) may contribute to reperfusion injury of the liver during liver transplantation or resection.
Baron, A.   +5 more
core   +1 more source

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