Results 21 to 30 of about 79,020 (262)
N-acetyl-cysteine, a drug that enhances the endogenous activation of group-II metabotropic glutamate receptors, inhibits nociceptive transmission in humans. [PDF]
, 2015 Emerging research seeking novel analgesic drugs focuses on agents targeting group-II metabotropic glutamate receptors (mGlu2 and mGlu3 receptors). N-Acetylcysteine (NAC) enhances the endogenous activation of mGlu2/3 receptors by activating the glial ...
BATTAGLIA, Giuseppe +8 more
core +1 more source
Вестник трансплантологии и искусственных органов, 2013 Aim. The purpose of our work was to estimate the impact of preconditioning with acetylcysteine and sevoflurane on ischemia-reperfusion injury of cadaveric donor liver with marginal features. Methods and results.
A. E. Shcherba +6 more
doaj +1 more source
The World Journal of Men's Health, 2023 Purpose: This study aimed to evaluate the protective effect of N-acetyl-L-cysteine (NAC) as an antioxidant on busulfaninduced testicular dysfunction in mice and elucidate its possible mechanism of action.
Kyung Hwan Kim +3 more
doaj +1 more source
Chromon-3-aldehyde derivatives restore mitochondrial function in rat cerebral ischemia [PDF]
Iranian Journal of Basic Medical Sciences, 2020 Objective(s): This work aimed to assess the effect of 10 new chromon-3-aldehyde derivatives on changes of mitochondrial function under the conditions of brain ischemia in rats.
Dmitry Pozdnyakov +2 more
doaj +1 more source
Pirfenidone treatment in idiopathic pulmonary fibrosis: A Saudi experience
Annals of Thoracic Medicine, 2015 Background: Recent trials involving pirfenidone suggest a beneficial effect in the treatment of idiopathic pulmonary fibrosis (IPF). Objective: To report on the efficacy and safety of pirfenidone in the treatment of patients with IPF, at a tertiary care
Esam H Alhamad
doaj +1 more source
Cardiovascular and hepatic toxicity of cocaine: potential beneficial effects of modulators of oxidative stress [PDF]
, 2015 Oxidative stress (OS) is thought to play an important role in the pharmacological and toxic effects of various drugs of abuse. Herein we review the literature on the mechanisms responsible for the cardiovascular and hepatic toxicity of cocaine with ...
Antonilli, Letizia +5 more
core +4 more sources
Protective Effect of N-Acetyl Cysteine on Chlorpyrifos-Induced Testicular Toxicity in Mice [PDF]
International Journal of Fertility and Sterility, 2019 Background Chlorpyrifos (CPF), an organophosphate pesticide, is widely used in farms in order to preserve crops and fruits. Previous studies have shown that CPF exposure might cause chronic toxicity in male genital system.
Rasoul Kheradmandi +4 more
doaj +1 more source
Cells, 2019 Systemic lupus erythematosus (SLE) is a chronic inflammatory autoimmune condition that can potentially affect every single organ during the course of the disease, leading to increased morbidity and mortality, and reduced health-related quality of life ...
Marcus Kai Xuan Tan +2 more
doaj +1 more source
Glutathione treatment protects the rat liver against injury after warm ischemia and Kupffer cell activation [PDF]
, 2002 Background/Aim: The generation of reactive oxygen species by activated Kupffer cells (KC) may contribute to reperfusion injury of the liver during liver transplantation or resection.
Baron, A. +5 more
core +1 more source
Metagenomic Sequencing Analysis of the Effects of Acetylcysteine on the Pig Gut Microbiome
Microbiology Research, 2023 The gut microbiota is engaged in multiple interactions affecting host health, and gut dysbiosis can lead to many diseases. However, the effects of acetylcysteine (NAC) on the gut microbiome composition in pigs using metagenomic sequencing have not been ...
Shulin Fu +10 more
doaj +1 more source