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Assessment of the cytotoxic, proapoptotic, and genotoxic effects of bromelain on human peripheral blood mononuclear cells [PDF]
Scientific ReportsBromelain, a proteolytic enzyme from pineapple, is a promising anticancer candidate due to its ability to induce apoptosis in various malignant cell lines.
Joanna Bernasinska-Slomczewska +2 more
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Protective role of bromelain’s antioxidant and anti-inflammatory effects in experimental lower limb ischemia-reperfusion injury [PDF]
Scientific ReportsIschemia-reperfusion (IR) injury is a multifaceted pathological process characterized by excessive oxidative stress and inflammatory responses upon restoration of blood flow. Bromelain, a proteolytic enzyme complex derived from pineapple, exhibits robust
Saban Cem Sezen +8 more
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A Review: Application of Bromelain Enzymes in Animal Food Products
Andalasian International Journal of Agricultural and Natural Sciences, 2023 This review focuses on the use of bromelain in various applications in animal products with the latest literature so that it can provide information on what parts of this enzyme can be applied. Bromelain is a protease enzyme found in stems (EC 3.4.22.32),
Ririn Fatma Nanda +4 more
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Antibiofilm activity of bromelain from pineapple against Staphylococcus aureus
Acta Scientiarum: Biological Sciences, 2023 Bromelain is a set of proteolytic enzymes usually obtained from pineapple (Ananas comosus). Although bromelain has distinguished therapeutic properties, little is known about its proteolytic potential against opportunistic pathogens related to wound ...
Michelle Pereira Silva +5 more
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Optimization of bromelain isolation from honi pineapple crown
International Journal of Food Studies, 2022 Bromelain is a proteolytic enzyme that can be found in all parts of pineapple plant varieties. Pineapple crown (PC) has higher bromelain activity than other pineapple wastes such as peels and leaves.
Siti Susanti +4 more
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Beneficial Properties of Bromelain [PDF]
Nutrients, 2021 Bromelain is a major sulfhydryl proteolytic enzyme found in pineapple plants, having multiple activities in many areas of medicine. Due to its low toxicity, high efficiency, high availability, and relative simplicity of acquisition, it is the object of inexhaustible interest of scientists.
Pawel Hikisz +1 more
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PLoS ONE, 2023 BackgroundColorectal cancer (CRC) is one of the most lethal cancers worldwide. Long-term survival is not achieved in metastatic CRC despite the current multidisciplinary therapies.
Kuei-Yen Tsai +7 more
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Medicina, 2021 Background and Objectives: Bromelain is a mixture of protease obtained from pineapple fruits or stems. Even though the biological mechanism of action of bromelain has not been completely understood, it is well known that bromelain possesses anticancer ...
Joo-Hyun Hong +6 more
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Identification of bromelain subfamily proteases encoded in the pineapple genome
Scientific Reports, 2023 Papain (aka C1A) family proteases, including bromelain enzymes, are widespread across the plant kingdom and play critical regulatory functions in protein turnover during development.
Ashley G. Yow +7 more
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Brazilian Archives of Biology and Technology, 2023 Bromelain is a mix of proteolytic enzymes obtained from the pineapple plant's fruit or stem. The effect of various rates of bromelain supplementation on broiler growth and carcass performance, meat quality, antioxidant metabolism, and blood profiles were
Güler Yenice +7 more
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