Results 31 to 40 of about 4,461 (180)

In Silico and In Vitro Study of the Bromelain-Phytochemical Complex Inhibition of Phospholipase A2 (Pla2)

Molecules, 2018
Phospholipase A2 (Pla2) is an enzyme that induces inflammation, making Pla2 activity an effective approach to reduce inflammation. Therefore, investigating natural compounds for this Pla2 inhibitory activity has important therapeutic potential.
Fatahiya Mohamed Tap, Fadzilah Adibah Abd Majid, Hassan Fahmi Ismail, Tet Soon Wong, Kamyar Shameli, Mikio Miyake, Nurul Bahiyah Ahmad Khairudin   +6 more
doaj   +1 more source

Composition and functionalities of peanut protein concentrates using ethanol as a defatted solvent and a precipitating agent

Journal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND Defatted solids (DSs) from vegetable oil extraction represent valuable feedstocks for producing protein concentrates with tailored functional properties. In the present study, using peanut protein concentrates obtained from press cakes defatted with ethanol (DSEt) or hexane (DSHx), we aimed to evaluate ethanol as a green solvent for
Paloma Jamily Cristina Magalhães, Luiza Cardoso Stumm, Paola de Cássia Franco Visioli, Keila Kazue Aracava, Rafaela Torrezan Privatti, Maria Carolina Capellini, Silvana Marina Piccoli Pugine, Daniel Gonçalves, Christianne Elisabete da Costa Rodrigues   +8 more
wiley   +1 more source

Bromelain regulates TRP channels to induce orofacial nociception relief in adult zebrafish

Biochemistry and Biophysics Reports
Bromelain, the main protease enzyme found in the pineapple plant (Ananas comosus), has had its antinociceptive effect previously demonstrated. This investigation aimed to appraise the role of TRP (Transient Receptor Potential) channels in the nociception-
Saulo Rodrigo Lucas Ribeiro, Sacha Aubrey Alves Rodrigues Santos, Ana Lívia Oliveira de Sousa Rodrigues, Gabriella Mesquita de Sena, Antônio Eufrásio Vieira-Neto, Adriana Rolim Campos   +5 more
doaj   +1 more source

Bioactive Natural Products in Cardiovascular Disease: Focus on Thrombotic Events

Phytotherapy Research, EarlyView.
An overview of the role of natural products (NP) in cardiovascular disease prevention, highlighting key mechanisms of action: including antiplatelet, antithrombotic, anti‐inflammatory, and antioxidant effects. Additionally, it illustrates the integration of diet–drug interactions, nutritional epigenetics, and the role of artificial intelligence in ...
Maria Nektaria Magkoulia, Despoina Pantazi   +1 more
wiley   +1 more source

Environmental Mycotoxins and Brain Health: Protective Role of Bromelain Against Fumonisin B1 in SH‐SY5Y Cells

Environmental Toxicology, EarlyView.
ABSTRACT Fumonisin B1 (FB1), a mycotoxin commonly found in contaminated food and feed, has been increasingly implicated in neurotoxicity, although its mechanisms remain poorly understood. This study investigates the neurotoxic potential of FB1 in human SH‐SY5Y neuroblastoma cells, both undifferentiated and RA‐differentiated, and evaluates the ...
Gianluca Antonio Franco, Francesca Inferrera, Nicla Tranchida, Davide Di Paola, Roberta Fusco, Salvatore Cuzzocrea, Enrico Gugliandolo   +6 more
wiley   +1 more source

Chemical agents to control biofilm formation in step 1 of care—Toothpastes and mouthwashes/concepts and challenges

Periodontology 2000, EarlyView.
Abstract Maintaining optimal oral hygiene is important for overall oral care, ensuring the well‐being of teeth and their surrounding tissues. In addition, it promotes fresh breath and a pleasing smile. A key element of oral self‐care is the daily use of toothpaste during regular brushing.
Maud Joosstens, Cees Valkenburg, Fridus Van der Weijden   +2 more
wiley   +1 more source

Effect of Proteolytic Enzymes and Ginger Extract on Tenderization of M. pectoralis profundus from Holstein Steer

Food Science of Animal Resources, 2018
The effects of proteolytic enzymes (bromelain and bromelain+papain) and a ginger extract were assessed on collagen content and solubility, thermal shrinkage temperature of connective tissue, pH, cooking loss, drip loss, and Warner-Bratzler shear force ...
Sung Sil Moon
doaj   +1 more source

Evaluation of the radiosensitizing potency of bromelain for radiation therapy of 4T1 breast cancer cells

Journal of Medical Signals and Sensors, 2019
Breast cancer (BC) remains the leading cause of death in women worldwide, despite the improvements of cancer screening and treatment methods. Recently, development of novel anticancer drugs for the improved prevention and treatment of BC is in the center
Farzaneh Raeisi, Daryoush Shahbazi-Gahrouei, Elham Raeisi, Esfandiar Heidarian   +3 more
doaj   +1 more source

Therapeutic Efficacy of Bromelain in Alveolar Ridge Preservation

Antibiotics, 2022
Most of research in regenerative oral surgery describes materials or techniques for increasing volumetric results for implant-supported prosthesis. The use of bio-materials in alveolar ridge preservation after tooth extraction commonly leads to a delayed
Glauco Chisci, Luca Fredianelli
doaj   +1 more source

Fucosylation limits ADCC in clinically used anti‐RhD monoclonal antibodies

Transfusion, EarlyView.
Abstract Background Haemolytic disease of the fetus and newborn (HDFN) is caused by maternal alloantibodies, often targeting the D antigen on fetal red blood cells. Maternal immunization is preventable with timely administration of anti‐D polyclonal antibodies (pAbs).
Gabriela Koike, Albert Bondt, Douwe Schulte, Rien Leuvenink, Dirk Jan Mons, Peter C. Ligthart, E. Joanne T. Verweij, AFRICARhE Consortium, Enrico Lopriore, E. J. T. Joanne Verweij, Tienke Vermeiden, Thomas van den Akker, C. Ellen van der Schoot, Derek P. de Winter, Renske van Oever, Abera Kenay Tura, Tadesse Gure, Assefa Desalew, Tewodros Tesfa, Konjit Eshetu, Jeremia Pyuza, Rafiki N. Mjema, Priscus John Mapendo, Jeremiah John Hhera, Bariki Mchome, Patricia Swai, Blandina T. Mmbaga, Aisa Shayo, Peter Moons, Kondwani Kawaza, Luis Gadama, Albert J. R. Heck, C. Ellen van der Schoot, Gestur Vidarsson   +33 more
wiley   +1 more source