Results 51 to 60 of about 88,160 (292)

Comparative evaluation of the effectiveness and safety of 12-hour and 21-hour protocols for the administration of acetylcysteine in paracetamol poisoning

Вестник анестезиологии и реаниматологии, 2023
Background. Acetylcysteine (ACC) is an effective antidote for paracetamol poisoning. There are various schemes for its application. At the same time, there is currently no information about the most priority of them in this pathology.
A. Yu. Simonova, M. M. Potskhveriya, M. V. Belova, K. K. Ilyashenko, V. V. Kulabukhov, L. R. Asanova   +5 more
doaj   +1 more source

Tailored Xenogeneic‐Free Polymer Surface Promotes Dynamic Migration of Intestinal Stem Cells

Advanced Materials, EarlyView.
This study introduces a PoLymer‐coated Ultra‐stable Surface (PLUS), a nitrogen plasma‐treated poly(ethyleneglycoldimethacrylate), as a stable xenogeneic‐free platform for intestinal stem cell culture. PLUS enhances cell attachment, supports actin‐driven migration, and retains functionality after 3 years of storage. Promoting cytoskeletal reorganization,
Seonghyeon Park, Sang Yu Sun, Jin Gyeong Son, Sun Young Lee, Hyun Kyong Shon, Ohman Kwon, Minseok Lee, Keonwoo Choi, Jemin Yeun, Sung Hyun Yoon, Minkyung Kim, Mi‐Young Son, Tae Geol Lee, Sung Gap Im   +13 more
wiley   +1 more source

In Vitro Culture of Vitrified Immature Mouse Testicular Tissue in The Presence of N-acetylcysteine Antioxidant [PDF]

International Journal of Fertility and Sterility
Background: Cryopreservation of immature testicular tissue is a suitable method for spermatogonial stem cell (SSC) preservation in prepubertal boys, who are at risk of infertility due to cancer treatments.
Parmiss Nikoosokhan, Zeinab Ghezelayagh, Samira Hajiaghalou, Alireza Alizadeh Moghadam Masouleh, Bita Ebrahimi   +4 more
doaj   +1 more source

Novel Use of Bromelain and Acetylcysteine (BromAc®) for Pleural Involvement in Pseudomyxoma Peritonei

Case Reports in Oncology, 2021
Pseudomyxoma peritonei (PMP) is a rare mucinous disease most commonly arising from the appendix. Pleural involvement arising from established PMP is seen in a small number of cases.
Anthony R. Lam, Khalil Bazzi, Sarah J. Valle, David L. Morris   +3 more
doaj   +1 more source

N-acetyl-cysteine, a drug that enhances the endogenous activation of group-II metabotropic glutamate receptors, inhibits nociceptive transmission in humans. [PDF]

, 2015
Emerging research seeking novel analgesic drugs focuses on agents targeting group-II metabotropic glutamate receptors (mGlu2 and mGlu3 receptors). N-Acetylcysteine (NAC) enhances the endogenous activation of mGlu2/3 receptors by activating the glial ...
BATTAGLIA, Giuseppe, CRUCCU, Giorgio, DI STEFANO, GIULIA, E. Pasquale, LATTANZI, Roberta, NICOLETTI, Ferdinando, PIROSO, SERENA, S. Notartomaso, TRUINI, ANDREA   +8 more
core   +1 more source

Curcumin and N-Acetylcysteine Nanocarriers Alone or Combined with Deferoxamine Target the Mitochondria and Protect against Neurotoxicity and Oxidative Stress in a Co-Culture Model of Parkinson’s Disease [PDF]

, 2023
Leah Mursaleen, Stefanie Ho Yi Chan, B Noble, Satyanarayana Somavarapu, Mohammed Gulrez Zariwala   +4 more
openalex   +1 more source

ROS Activated NETosis of Bone Marrow CD55+ Intermediate Mature Neutrophils Through HIF1α‐PADI4 Pathway to Initiate Bone Aging

Advanced Science, EarlyView.
In this study, we find CD55+ neutrophils show activated NETosis within bone marrow, induce BMSC senescence and osteogenesis inhibition, finally leading to bone aging initiation. Mechanistically, ROS synergizes with the CD55‐driven HIF1α‐PADI4 pathway to promote NETosis.
Yutong Guo, Shengjie Cui, Xi Wen, Yidi Wang, Ben Wu, Yixiang Wang, Yan Gu   +6 more
wiley   +1 more source

Effectiveness assessment of sulfur-containing amino acids in rats with experimental “alcohol withdrawal syndrome” with modified zoosocial interaction methods

Фармация и фармакология (Пятигорск)
The aim of the work was to compare the effects of ademethionine, acetylcysteine and taurine on the zoosocial behavior of rats in a post-intoxicated state after an acute ethanol poisoning.Materials and methods.
V. I. Petrov, N. A. Osadchenko, A. S. Tarasov, A. M. Dotsenko, E. I. Morkovin   +4 more
doaj   +1 more source

Correction of psychological and neurological signs of alcohol hangover in rats with acetylcysteine

Фармация и фармакология (Пятигорск), 2019
The development of medications to treat alcohol hangover is important for a large number of people, especially those, who perform responsible and dangerous types of work.
D. V. Kurkin, E. I. Morkovin, N. A. Osadchenko, L. P. Knyshova, D. A. Bakulin, E. E. Abrosimova, Yu. V. Gorbunova, I. N. Tyurenkov   +7 more
doaj   +1 more source

Fungistatic Action of N-Acetylcysteine on Candida albicans Biofilms and Its Interaction with Antifungal Agents

Microorganisms, 2020
Therapies targeted to fungal biofilms, mainly against the matrix, and therapies that do not induce microbial resistance are relevant. N-acetylcysteine (NAC), a mucolytic agent, has shown antimicrobial action.
Thaís Soares Bezerra Santos Nunes, Leticia Matheus Rosa, Yuliana Vega-Chacón, Ewerton Garcia de Oliveira Mima   +3 more
doaj   +1 more source