Results 61 to 70 of about 79,020 (262)

Targeting Peptostreptococcus anaerobius with an Iron‐Based Nanozyme Reverses Ferroptosis Resistance and Enhances Antitumor Immunity in Colorectal Cancer

open access: yesAdvanced Science, EarlyView.
An iron‐based nanozyme selectively eliminates intratumoral P. anaerobius while catalytically generating ROS to induce ferroptosis, synergistically suppressing colorectal cancer growth and activating anti‐tumor immunity through immunogenic cell death. ABSTRACT The intratumoral microbiota is a critical determinant of therapeutic outcomes in colorectal ...
Yinghao Cao   +11 more
wiley   +1 more source

Effectiveness assessment of sulfur-containing amino acids in rats with experimental “alcohol withdrawal syndrome” with modified zoosocial interaction methods

open access: yesФармация и фармакология (Пятигорск)
The aim of the work was to compare the effects of ademethionine, acetylcysteine and taurine on the zoosocial behavior of rats in a post-intoxicated state after an acute ethanol poisoning.Materials and methods.
V. I. Petrov   +4 more
doaj   +1 more source

Correction of psychological and neurological signs of alcohol hangover in rats with acetylcysteine

open access: yesФармация и фармакология (Пятигорск), 2019
The development of medications to treat alcohol hangover is important for a large number of people, especially those, who perform responsible and dangerous types of work.
D. V. Kurkin   +7 more
doaj   +1 more source

Fungistatic Action of N-Acetylcysteine on Candida albicans Biofilms and Its Interaction with Antifungal Agents

open access: yesMicroorganisms, 2020
Therapies targeted to fungal biofilms, mainly against the matrix, and therapies that do not induce microbial resistance are relevant. N-acetylcysteine (NAC), a mucolytic agent, has shown antimicrobial action.
Thaís Soares Bezerra Santos Nunes   +3 more
doaj   +1 more source

Effect of Nebulized BromAc on Rheology of Artificial Sputum: Relevance to Muco-Obstructive Respiratory Diseases

open access: yesAdvances in Respiratory Medicine, 2023
Respiratory diseases such as cystic fibrosis, COPD, and COVID-19 are difficult to treat owing to viscous secretions in the airways that evade mucocilliary clearance. Earlier studies have shown success with BromAc as a mucolytic agent.
Krishna Pillai   +3 more
doaj   +1 more source

Inhibition of SIRT7 Overcomes Radioresistance in Pancreatic Neuroendocrine Tumors by Reactivating MEN1 Expression

open access: yesAdvanced Science, EarlyView.
Pancreatic neuroendocrine tumors frequently silence MEN1 through epigenetic mechanisms. Here, SIRT7 recruits DNMT1 to the MEN1 promoter, drives hypermethylation, and enhances DNA repair. Inhibiting SIRT7 restores MEN1, reduces MRN complex abundance, impairs double‐strand break repair, and sensitizes PanNET models to radiation, supporting SIRT7 as a ...
Jianyun Jiang   +11 more
wiley   +1 more source

Simple Answers to Complex Questions about Mucolytics for Children

open access: yesВопросы современной педиатрии, 2015
The article discusses the use of N-acetylcysteine in pediatric practice and examines various clinical effects of acetylcysteine, including in acute respiratory infections in children, and peculiarities of its application. The causes for the phenomenon of
O. I. Simonova
doaj   +1 more source

Intrabiliary Acetylcysteine Infusion for Biliary Obstruction in a Case of Chronic Pancreatitis with Pancreatic Head IPMN

open access: yesJournal of Digestive Endoscopy, 2020
Successful biliary drainage in case of intraductal papillary mucinous neoplasm (IPMN) with thick mucus by ERCP and internal drainage alone is usually inadequate.
Paul K. Vincent   +4 more
doaj   +1 more source

Sample Preparation for Determination of Biological Thiols by Liquid Chromatography and Electromigration Techniques [PDF]

open access: yes, 2004
Wydrukowano z dostarczonych Wydawnictwu UŁ gotowych materiałówMajority of the bioanalytical or environmental methods do not use just one chromatografie or electrophoretic step, but rather involve several sample pretreatment steps which simplfy the ...
Bald, Edward
core  

A systematic review of neuroprotective strategies after cardiac arrest: from bench to bedside (Part I - Protection via specific pathways). [PDF]

open access: yes, 2014
Neurocognitive deficits are a major source of morbidity in survivors of cardiac arrest. Treatment options that could be implemented either during cardiopulmonary resuscitation or after return of spontaneous circulation to improve these neurological ...
Applegate, Patricia M   +5 more
core   +2 more sources

Home - About - Disclaimer - Privacy