Results 1 to 10 of about 409 (87)
Beilstein Journal of Organic Chemistry, 2018 Synthetic approaches towards N-acetylgalactosamine (GalNAc) have been attracting considerable interest since this compound is known for its pivotal role in cell–cell interaction and receptor induced cell signaling. Herein, we present a synthetic route in
Bettina Riedl, Walther Schmid
exaly +2 more sources
Understanding Aspergillus fumigatus galactosaminogalactan biosynthesis: A few questions remain
The Cell Surface, 2023 Half a century after their discovery, polymers of N-acetylgalactosamine produced by the Aspergilli have garnered new interest as mediators of fungal virulence.
François Le Mauff, Donald C. Sheppard
doaj +1 more source
Terminal N-acetylgalactosamine-specific leguminous lectin from Wisteria japonica as a probe for human lung squamous cell carcinoma. [PDF]
PLoS ONE, 2013 Millettia japonica was recently reclassified into the genus Wisteria japonica based on chloroplast and nuclear DNA sequences. Because the seed of Wisteria floribunda expresses leguminous lectins with unique N-acetylgalactosamine-binding specificity, we ...
Keisuke Soga +4 more
doaj +1 more source
Characterization of a novel exonic deletion in the GALNS gene causing Morquio A syndrome
Molecular Genetics and Metabolism Reports, 2022 Mucopolysaccharidosis IVA or Morquio A syndrome is a rare lysosomal storage disorder caused by N-acetylgalactosamine-6-sulfatase deficiency. A diagnosis can be provided by the identification of reduced N-acetylgalactosamine-6-sulfatase activity as well ...
Kathryn DeLong +4 more
doaj +1 more source
Investigation of prostate specific antigen glycosylation [PDF]
Journal of the Serbian Chemical Society, 2000 In the present work, prostate specific antigen (PSA) glycosylation was examined by lectin affinity methods. The results obtained indicated that PSA purified from human seminal plasma contained at least one bianntenary N-linked oligosaccharide ...
Marinović Vesna, Čuperlović Margita
doaj +1 more source
Biomolecules, 2020 The chondroitin sulfate (CS)-rich dense extracellular matrix surrounding neuron cell bodies and proximal dendrites in a mesh-like structure is called a perineuronal net (PNN).
Satomi Nadanaka +5 more
doaj +1 more source
The therapeutic prospects of N-acetylgalactosamine-siRNA conjugates
Frontiers in Pharmacology, 2022 RNA interference has become increasingly used for genetic therapy following the rapid development of oligonucleotide drugs. Significant progress has been made in its delivery system and implementation in the treatment of target organs.
Lei Zhang +6 more
doaj +1 more source
A lectin histochemical study of the thoracic respiratory air sacs of the fowl
Onderstepoort Journal of Veterinary Research, 2005 The lectin-binding characteristics of the epithelial lining of the thoracic air sacs of the chicken were determined. Con A, LCA and PSA bound to the apical membrane as well as to the cytoplasm distal to the nucleus of the surface epithelium, indicated
A.J. Bezuidenhout
doaj +1 more source
O-Glycosylation of NnTreg Lymphocytes Recognized by the Amaranthus leucocarpus Lectin
Clinical and Developmental Immunology, 2013 O-glycosidically-linked glycans have been involved in development, maturation, homing, and immune regulation in T cells. Previous reports indicate that Amaranthus leucocarpus lectin (ALL), specific for glycans containing galactose-N-acetylgalactosamine ...
María C. Jiménez-Martínez +8 more
doaj +1 more source
Isolation and partial characterisation of a novel lectin from Aegle marmelos fruit and its effect on adherence and invasion of Shigellae to HT29 cells. [PDF]
PLoS ONE, 2011 Lectins are a class of ubiquitous proteins/glycoproteins that are abundantly found in nature. Lectins have unique carbohydrate binding property and hence have been exploited as drugs against various infectious diseases.
Subramaniya Bharathi Raja +3 more
doaj +1 more source