Results 151 to 160 of about 218,218 (394)

Compensation Response to Hepatic Gluconeogenesis via β‐Hydroxybutyrylation of FBP1 and PCK1 in Dairy Cows

open access: yesAnimal Research and One Health, EarlyView.
(1) Kbhb modification of FBP1 and PCK1 is involved in regulation of the gluconeogenesis pathway. (2) Kbhb of FBP1 and PCK1 is catalyzed by p300 and removed by HDACs. (3) BHB induced an increase in the enzymatic activity of FBP1 and PCK1 through Kbhb modification at the K43 site of FBP1 and the K191 site of PCK1.
DingPing Feng   +6 more
wiley   +1 more source

Choline acetyltransferase detection in normal and denervated electrocyte from Electrophorus electricus (L.) using a Confocal Scanning Optical Microscopy Analysis

open access: yesAnais da Academia Brasileira de Ciências, 2000
Acetylcholine is the neurotransmitter responsible for the transmission of impulses from cholinergic neurons to cells of innervated tissues. Its biosynthesis is catalyzed by the enzyme Choline acetyltransferase that is considered to be a phenotypically ...
NILSON NUNES-TAVARES   +2 more
doaj   +1 more source

Histone acetyltransferase PCAF is required for Hedgehog-Gli-dependent transcription and cancer cell proliferation.

open access: yesCancer Research, 2013
The Hedgehog (Hh) signaling pathway plays an important role in embryonic patterning and development of many tissues and organs as well as in maintaining and repairing mature tissues in adults.
M. Malatesta   +5 more
semanticscholar   +1 more source

Construction and Characterization of Novel Shuttle Expression Vectors for Actinobacillus succinogenes

open access: yesBiotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Actinobacillus succinogenes is a ruminal microorganism of biotechnological importance due to its capacity to produce succinic acid at high yields. Despite the scientific interest in this organism, molecular vehicles for the transfer and expression of genetic material are limited compared to the existing demand.
Angélica Vallejo‐Giraldo   +7 more
wiley   +1 more source

Evaluation of the endogenous glucocorticoid hypothesis of denervation atrophy [PDF]

open access: yes
The effects are studied of the oral administration of RU38486, a potent selective glucocorticoid antagonist, on muscle weight, non-collagen protein content, and selected enzyme activities (choline acetyltransferase, glucose 6-phosphate dehydrogenase, and
Konagaya, Masaaki   +2 more
core   +1 more source

Applicability of tandem affinity purification MudPIT to pathway proteomics in yeast [PDF]

open access: yes, 2004
A combined multidimensional chromatography-mass spectrometry approach known as "MudPIT" enables rapid identification of proteins that interact with a tagged bait while bypassing some of the problems associated with analysis of polypeptides excised from ...
Deshaies, Raymond J.   +6 more
core   +1 more source

Biotechnological production of 2‐phenylethanol from agroindustrial byproducts: experimental evaluation, techno‐economic analysis, and life cycle assessment

open access: yesBiofuels, Bioproducts and Biorefining, EarlyView.
Abstract 2‐Phenylethanol (2‐PE) is an alcohol with a rosy scent, commonly used as a fragrance, flavoring agent, and preservative in food and cosmetics. This study evaluates 2‐PE bioproduction using apple pomace and whey as low‐cost, biobased substrates for the growth of the yeast strain Kluyveromyces marxianus CBS600.
Fernanda Thimoteo Azevedo Jorge   +7 more
wiley   +1 more source

Safety of sulfamethoxazole–trimethoprim for the treatment of bacterial infection in outpatient settings: A systematic review and meta‐analysis with active comparator disproportionality analysis

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Sulfamethoxazole–trimethoprim (SMX‐TMP) is a widely used antibiotic for treating bacterial infections, but its safety in adult outpatients remains understudied. This systematic review and meta‐analysis evaluated the safety profile of SMX‐TMP and identified critical research gaps.
Rebecca Preyra   +4 more
wiley   +1 more source

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