The Acetyltransferase p300/CBP-Associated Factor Is a p53 Target Gene in Breast Tumor Cells
Neoplasia: An International Journal for Oncology Research, 2004 p300/CBP-associated factor (PCAF) is a coactivator of the tumor suppressor, p53. PCAF participates in p53's transactivation of target genes through acetylation of both bound p53 and histones within p53 target promoters.
George S. Watts +6 more
doaj +1 more source
Identification of critical residues of the serotype modifying O-acetyltransferase of Shigella flexneri [PDF]
, 2016 BACKGROUND Thirteen serotypes of Shigella flexneri (S. flexneri) have been recognised, all of which are capable of causing bacillary dysentery or shigellosis. With the emergence of the newer S.
Thanweer, Farzaana, Verma, Naresh K
core +1 more source
NAT1 (N-acetyltransferase 1 (arylamine N-acetyltransferase)) [PDF]
Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2011 Review on NAT1 (N-acetyltransferase 1 (arylamine N-acetyltransferase)), with data on DNA, on the protein encoded, and where the gene is implicated.
Ruiz, JD +3 more
openaire +2 more sources
NAT2 (N-acetyltransferase 2 (arylamine N-acetyltransferase)) [PDF]
Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2011 Review on NAT2 (N-acetyltransferase 2 (arylamine N-acetyltransferase)), with data on DNA, on the protein encoded, and where the gene is implicated.
Ruiz, JD +3 more
openaire +2 more sources
A four-month gatifloxacin-containing regimen for treating tuberculosis. [PDF]
, 2014 BACKGROUND: Shortening the course of treatment for tuberculosis would be a major improvement for case management and disease control. This phase 3 trial assessed the efficacy and safety of a 4-month gatifloxacin-containing regimen for treating rifampin ...
Amukoye, Evans +19 more
core +1 more source
Decreased sensitivity to aspirin is associated with altered polyamine metabolism in human prostate cancer cells [PDF]
, 2015 Acknowledgments We thank NHS Grampian for financial support of this work.Peer reviewedPublisher ...
Cameron, Gary A. +2 more
core +1 more source
Gcn5 histone acetyltransferase is present in the mitoplasts [PDF]
, 2019 In Saccharomyces cerevisiae the Lysine-acetyltransferase Gcn5 (KAT2) is part of the SAGA complex and is responsible for histone acetylation widely or at specific lysines.
De Luca, Veronica +4 more
core +1 more source
The Role of Histone Protein Acetylation in Regulating Endothelial Function
Frontiers in Cell and Developmental Biology, 2021 Endothelial cell (EC), consisting of the innermost cellular layer of all types of vessels, is not only a barrier composer but also performing multiple functions in physiological processes.
Zhi Fang +5 more
doaj +1 more source
The influence of non-neuronal cells on catecholamine and acetylcholine synthesis and accumulation in cultures of dissociated sympathetic neurons [PDF]
, 1974 The effects of several non-neuronal cell types on neurotransmitter synthesis in cultures of dissociated sympathetic neurons from the new-born rat were studied.
Chun, Linda L. Y., Patterson, Paul H.
core +1 more source
Histone acetyltransferase inhibitor CPTH6 preferentially targets lung cancer stem-like cells [PDF]
, 2016 Cancer stem cells (CSCs) play an important role in tumor initiation, progression, therapeutic failure and tumor relapse. In this study, we evaluated the efficacy of the thiazole derivative 3-methylcyclopentylidene-[4-(4’-chlorophenyl)thiazol-2-yl ...
Buglioni, Simonetta +14 more
core +4 more sources