Kinesin-II is required for axonal transport of choline acetyltransferase in Drosophila [PDF]
, 1999 KLP64D and KLP68D are members of the kinesin-II family of proteins in Drosophila. Immunostaining for KLP68D and ribonucleic acid in situ hybridization for KLP64D demonstrated their preferential expression in cholinergic neurons.
Address Lawrence +8 more
core +4 more sources
Pyrophosphate-Dependent ATP Formation from Acetyl Coenzyme A in Syntrophus aciditrophicus, a New Twist on ATP Formation. [PDF]
, 2016 UnlabelledSyntrophus aciditrophicus is a model syntrophic bacterium that degrades key intermediates in anaerobic decomposition, such as benzoate, cyclohexane-1-carboxylate, and certain fatty acids, to acetate when grown with hydrogen-/formate-consuming ...
Erde, Jonathan +17 more
core +2 more sources
Scientific Reports, 2019 Drought episodes decrease plant growth and productivity, which in turn cause high economic losses. Plants naturally sense and respond to water stress by activating specific signalling pathways leading to physiological and developmental adaptations ...
Joaquin Felipe Roca Paixao +8 more
semanticscholar +1 more source
Acetyltransferases GCN5 and PCAF Are Required for B Lymphocyte Maturation in Mice
Biomolecules, 2021 B lymphocyte development has two DNA recombination processes: V(D)J recombination of the immunoglobulin (Igh) gene variable region, and class switching of the Igh constant regions from IgM to IgG, IgA, or IgE.
Valentyn Oksenych +2 more
doaj +1 more source
A Yeast Polyamine Acetyltransferase [PDF]
Journal of Biological Chemistry, 2005 An uncharacterized yeast gene has been shown to encode a polyamine acetyltransferase and named PAA1. The recombinant Paa1 protein readily acetylates various polyamines such as putrescine, spermidine, and spermine. paa1 mutants are viable and grow normally under standard conditions.
Rolf Sternglanz +2 more
openaire +3 more sources
Acetyltransferase GCN5 regulates autophagy and lysosome biogenesis by targeting TFEB
EMBO Reports, 2019 Accumulating evidence highlights the role of histone acetyltransferase GCN5 in the regulation of cell metabolism in metazoans. Here, we report that GCN5 is a negative regulator of autophagy, a lysosome‐dependent catabolic mechanism.
Yusha Wang +8 more
semanticscholar +1 more source
The Use of Plasmapheresis in Treatment of Patients with Infertility, Peritoneal Endometriosis and Nat2 Gene Polymorphism [PDF]
, 2016 It is known that 30–40 % of patients with peritoneal endometriosis suffer from infertility. Half of the patients with endometriosis are identified point mutation in NAT2 – gene, which plays an important role in the acetylation of aromatic and ...
Dubinskaya, E. (Ekaterina) +2 more
core +2 more sources
BRD4 is a Histone Acetyltransferase that Evicts Nucleosomes from Chromatin
Nature Structural &Molecular Biology, 2016 Bromodomain protein 4 (BRD4) is a chromatin-binding protein implicated in cancer and autoimmune diseases that functions as a scaffold for transcription factors at promoters and super-enhancers.
B. N. Devaiah +8 more
semanticscholar +1 more source
Identification of Novel Protein Lysine Acetyltransferases in
mBio, 2018 Posttranslational modifications, such as Nε-lysine acetylation, regulate protein function. Nε-lysine acetylation can occur either nonenzymatically or enzymatically.
David G. Christensen +8 more
doaj +1 more source
A role for human N-alpha acetyltransferase 30 (Naa30) in maintaining mitochondrial integrity [PDF]
, 2016 N-terminal acetylation (Nt-acetylation) by N-terminal acetyltransferases (NATs) is one of the most common protein modifications in eukaryotes. The NatC complex represents one of three major NATs of which the substrate profile remains largely unexplored ...
Arnesen, Thomas +8 more
core +2 more sources