Results 331 to 340 of about 218,218 (394)

A guide to heat shock factors as multifunctional transcriptional regulators

open access: yesThe FEBS Journal, EarlyView.
The heat shock factors (HSFs) are evolutionarily conserved transcription factors best known as regulators of molecular chaperone genes in response to heat shock and other protein‐damaging stresses. Vertebrate HSFs, HSF1‐5, HSFX, and HSFY, are implicated in various physiological and pathological processes, including organismal development and cancer ...
Hendrik S. E. Hästbacka   +3 more
wiley   +1 more source

The N-Acetyltransferase 2 Polymorphism and Susceptibility to Inflammatory Bowel Disease: A Case-Control Study. [PDF]

open access: yesPharmacol Res Perspect
Petryszyn P   +9 more
europepmc   +1 more source

Uhrf1 downregulation promotes β‐cell dedifferentiation by decreasing Foxo1 expression in type 2 diabetes

open access: yesJournal of Diabetes Investigation, EarlyView.
This finding reveals the important role of Uhrf1 in the β‐cell dedifferentiation of T2D, providing a potential target for its treatment. ABSTRACT Background Islet β‐cell dedifferentiation is a major pathological mechanism of type 2 diabetes (T2D). Forkhead box o1 (Foxo1) is a master regulator of β‐cell dedifferentiation.
Lanfang Fu   +3 more
wiley   +1 more source

Backbone resonance assignments of dopamine N-acetyltransferase in free and cofactor-bound states. [PDF]

open access: yesBiomol NMR Assign
Wu CY   +8 more
europepmc   +1 more source

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