Results 61 to 70 of about 218,218 (394)

Plant Cell Wall Polysaccharide O-Acetyltransferases

Plants
Plant cell walls are largely composed of polysaccharide polymers, including cellulose, hemicelluloses (xyloglucan, xylan, mannan, and mixed-linkage β-1,3/1,4-glucan), and pectins.
Ruiqin Zhong, Dayong Zhou, Lirong Chen, John P. Rose, Bi-Cheng Wang, Zheng-Hua Ye   +5 more
doaj   +1 more source

Reduced Toxicity of Trichothecenes, Isotrichodermol, and Deoxynivalenol, by Transgenic Expression of the Tri101 3-O-Acetyltransferase Gene in Cultured Mammalian FM3A Cells

Toxins, 2019
In trichothecene-producing fusaria, isotrichodermol (ITDol) is the first intermediate with a trichothecene skeleton. In the biosynthetic pathway of trichothecene, a 3-O-acetyltransferase, encoded by Tri101, acetylates ITDol to a less-toxic intermediate ...
Nozomu Tanaka, Ryo Takushima, Akira Tanaka, Ayaki Okada, Kosuke Matsui, Kazuyuki Maeda, Shunichi Aikawa, Makoto Kimura, Naoko Takahashi-Ando   +8 more
doaj   +1 more source

Acetylation and Deacetylation of DNA Repair Proteins in Cancers

Frontiers in Oncology, 2020
Hundreds of DNA repair proteins coordinate together to remove the diverse damages for ensuring the genomic integrity and stability. The repair system is an extensive network mainly encompassing cell cycle arrest, chromatin remodeling, various repair ...
Shiqin Li, Bingbing Shi, Xinli Liu, Han-Xiang An   +3 more
doaj   +1 more source

The autoepitope of the 74-kD mitochondrial autoantigen of primary biliary cirrhosis corresponds to the functional site of dihydrolipoamide acetyltransferase. [PDF]

, 1988
Autoantibodies to mitochondrial antigens are characteristic of the autoimmune liver disease primary biliary cirrhosis (PBC), but the precise antigenic determinants recognized by these antibodies have not been defined.
Ansari, A, Coppel, R, Gershwin, M, Leung, P, Van De Water, Judith   +4 more
core  

On the role of residue phosphorylation in 14-3-3 partners: AANAT as a case study [PDF]

, 2017
Twenty years ago, a novel concept in protein structural biology was discovered: the intrinsically disordered regions (IDRs). These regions remain largely unstructured under native conditions and the more are studied, more properties are attributed to ...
Bustos, Diego Martin, Masone, Diego Fernando, Uhart, Marina   +2 more
core   +2 more sources

Decoding the dual role of autophagy in cancer through transcriptional and epigenetic regulation

FEBS Letters, EarlyView.
Transcriptional and epigenetic regulation controls autophagy, which exerts context‐dependent effects on cancer: Autophagy suppresses tumorigenesis by maintaining cellular homeostasis or promotes tumor progression by supporting survival under stress. In this “In a Nutshell” article, we explore the intricate mechanisms of the dual function of autophagy ...
Young Suk Yu, Ik Soo Kim, Sung Hee Baek
wiley   +1 more source

smu_1558c-mediated regulation of growth and biofilm formation in Streptococcus mutans

Frontiers in Microbiology
Streptococcus mutans is a key etiological agent in dental caries, owing to its strong ability to form biofilms through carbohydrate fermentation. Protein acetylation, facilitated by GNAT family acetyltransferases, plays a critical regulatory role in ...
Jing Zhou, Jing Zhou, Qizhao Ma, Qizhao Ma, Jingou Liang, Jingou Liang, Yangyang Pan, Yangyang Pan, Yang Chen, Yang Chen, Shuxing Yu, Shuxing Yu, Yaqi Liu, Yaqi Liu, Qiong Zhang, Qiong Zhang, Yuqing Li, Jing Zou, Jing Zou   +18 more
doaj   +1 more source

Lifespan-increasing drug nordihydroguaiaretic acid inhibits p300 and activates autophagy. [PDF]

, 2019
Aging is characterized by the progressive loss of physiological function in all organisms. Remarkably, the aging process can be modulated by environmental modifications, including diet and small molecules.
Andersen, Julie, Butler, Victoria J, Chamoli, Manish, Jung, Manfred, Kao, Aimee W, Ng, Che-Ping, Simon, Roman P, Tezil, Tugsan, Verdin, Eric   +8 more
core  

Decreased sensitivity to aspirin is associated with altered polyamine metabolism in human prostate cancer cells [PDF]

, 2015
Acknowledgments We thank NHS Grampian for financial support of this work.Peer reviewedPublisher ...
Cameron, Gary A., Li, Jun, Wallace, Heather M.   +2 more
core   +1 more source

Inactivating mutations of acetyltransferase genes in B-cell lymphoma

Nature, 2010
B-cell non-Hodgkin’s lymphoma comprises biologically and clinically distinct diseases the pathogenesis of which is associated with genetic lesions affecting oncogenes and tumour-suppressor genes.
L. Pasqualucci, D. Dominguez-Sola, A. Chiarenza, G. Fabbri, A. Grunn, V. Trifonov, L. Kasper, Stephanie L. Lerach, Hongyan Tang, Jing Ma, D. Rossi, A. Chadburn, V. Murty, C. Mullighan, G. Gaidano, R. Rabadán, Paul K. Brindle, R. Dalla-Favera   +17 more
semanticscholar   +1 more source