Results 121 to 130 of about 95,792 (372)

Regulation of transcription by the Arabidopsis UVR8 photoreceptor involves a specific histone modification [PDF]

, 2016
The photoreceptor UV RESISTANCE LOCUS 8 (UVR8) specifically mediates photomorphogenic responses to UV-B wavelengths. UVR8 acts by regulating transcription of a set of genes, but the underlying mechanisms are unknown. Previous research indicated that UVR8
Herzyk, Pawel, Jenkins, Gareth I., Velanis, Christos N.   +2 more
core   +1 more source

TARDBP (TDP‐43) Knock‐in Zebrafish Display a Late‐Onset Motor Phenotype and Loss of Large Spinal Cord Motor Neurons

Annals of Neurology, EarlyView.
Objective Mutations in TARDBP (encoding TDP‐43) are associated with the neurodegenerative disease amyotrophic lateral sclerosis (ALS) and include familial missense mutations where there are a lack of models and mechanisms examining how they are pathogenic.
Ziyaan A. Harji, Christian J. Rampal, Esteban C. Rodríguez, Virginie Petel Légaré, Alexandra Lissouba, Sabrina Semmler, Meijiang Liao, Jay P. Ross, Guy A. Rouleau, Christine Vande Velde, Gary A.B. Armstrong   +10 more
wiley   +1 more source

CBP/p300 lysine acetyltransferases inhibit HIV-1 expression in latently infected T cells

iScience
Summary: HIV-1 latency is regulated by chromatin modifying enzymes, and histone deacetylase inhibitors (HDACi) cause reactivation of provirus expression.
Riley M. Horvath, Ivan Sadowski
doaj   +1 more source

Horizontal gene transfer contributes to plant evolution : the case of Agrobacterium T-DNAs [PDF]

, 2017
Horizontal gene transfer (HGT) can be defined as the acquisition of genetic material from another organism without being its offspring. HGT is common in the microbial world including archaea and bacteria, where HGT mechanisms are widely understood and ...
Gheysen, Godelieve, Kreuze, Jan F, Quispe Huamanquispe, Dora   +2 more
core   +1 more source

Histone acetyltransferases and histone deacetylases in B- and T-cell development, physiology and malignancy

Genes & cancer, 2015
The development of B and T cells from hematopoietic precursors and the regulation of the functions of these immune cells are complex processes that involve highly regulated signaling pathways and transcriptional control.
Leila Haery, Ryan C. Thompson, T. Gilmore   +2 more
semanticscholar   +1 more source

Diabetes Primes Neutrophils for Neutrophil Extracellular Trap Formation through Trained Immunity

Research
Neutrophils are primed for neutrophil extracellular trap (NET) formation during diabetes, and excessive NET formation from primed neutrophils compromises wound healing in patients with diabetes.
Sanjeeb Shrestha, Yu-Bin Lee, Hoyul Lee, Yeon-Kyung Choi, Bo-Yoon Park, Mi-Jin Kim, Young-Jin Youn, Sun-Hwa Kim, Soo-Jung Jung, Dong-Keun Song, Hee Kyung Jin, Jae-Sung Bae, In-Kyu Lee, Jae-Han Jeon, Chang-Won Hong   +14 more
doaj   +1 more source

Compensation Response to Hepatic Gluconeogenesis via β‐Hydroxybutyrylation of FBP1 and PCK1 in Dairy Cows

Animal Research and One Health, EarlyView.
(1) Kbhb modification of FBP1 and PCK1 is involved in regulation of the gluconeogenesis pathway. (2) Kbhb of FBP1 and PCK1 is catalyzed by p300 and removed by HDACs. (3) BHB induced an increase in the enzymatic activity of FBP1 and PCK1 through Kbhb modification at the K43 site of FBP1 and the K191 site of PCK1.
DingPing Feng, GuoYan Wang, YuanYuan Zhu, YiNing Zheng, JunHu Yao, Lei Chen, Lu Deng   +6 more
wiley   +1 more source

Supplementary Table 2 from N-acetyltransferase 2 Phenotype, Occupation, and Bladder Cancer Risk: Results from the EPIC Cohort [PDF]

, 2023
Beate Pesch, Katarzyna Gawrych, Sylvia Rabstein, Tobias Weiß, Swaantje Casjens, Hans‐Peter Rihs, Hui Ding, J. Angerer, Thomas Illig, Norman Klopp, Bas Bueno‐de‐Mesquita, Martine M. Ros, Rudolf Kaaks, Jenny Chang‐Claude, Nina Roswall, Anne Tjønneland, Kim Overvad, Françoise Clavel-Chapelon, Marie‐Christine Boutron‐Ruault, Laure Dossus, Heiner Boeing, Steffen Weikert, Dimitrios Trichopoulos, Domenico Palli, Sabina Sieri, ­Rosario ­Tumino, Salvatore Panico, J. Ramón Quirós, Carlos A. González, María‐José Sánchez, Miren Dorronsoro, Carmen Navarro, Aurelio Barricarte, Börje Ljungberg, Mattias Johansson, David Ulmert, Roy Ehrnström, Kay‐Tee Khaw, Nicholas J. Wareham, Timothy J. Key, Pietro Ferrari, Isabelle Romieu, Elio Ríboli, Thomas Brüning, Paolo Vineis   +44 more
openalex   +1 more source

Defining the Orphan Functions of Lysine Acetyltransferases

ACS Chemical Biology, 2015
Long known for their role in histone acetylation, recent studies have demonstrated that lysine acetyltransferases also carry out distinct “orphan” functions.
David C. Montgomery, Alexander W. Sorum, J. Meier   +2 more
semanticscholar   +1 more source

Exploring the Roles of Tuna‐Associated Acinetobacter sp. YFT067: Implications for Host Health and Metabolism

Animal Research and One Health, EarlyView.
This study firstly isolated a tuna‐derived gut probiotic Acinetobacter seifertii YFT067. Dietary administration of YFT067 played significant roles in promoting growth performance, SCFAs production, lipid absorption, and metabolism of the host, indicating YFT067 as a promising probiotic candidate for enhancing tuna aquaculture productivity through ...
Ying Zou, Hai Huang, Qiongyao Fu, Zhiyuan Lu, Zhiqiang Guo   +4 more
wiley   +1 more source