Results 141 to 150 of about 93,058 (385)

Arylamine N-acetyltransferases: from drug metabolism and pharmacogenetics to drug discovery

open access: yesBritish Journal of Pharmacology, 2014
Arylamine N‐acetyltransferases (NATs) are polymorphic drug‐metabolizing enzymes, acetylating arylamine carcinogens and drugs including hydralazine and sulphonamides.
E. Sim   +4 more
semanticscholar   +1 more source

Dysregulation of Histone Acetyltransferases and Deacetylases in Cardiovascular Diseases

open access: yesOxidative Medicine and Cellular Longevity, 2014
Cardiovascular disease (CVD) remains a leading cause of mortality worldwide despite advances in its prevention and management. A comprehensive understanding of factors which contribute to CVD is required in order to develop more effective treatment ...
Yonggang Wang   +6 more
semanticscholar   +1 more source

Nuclear parcellation of pontine catecholaminergic and cholinergic neurons in gray parrots and pied crow brains

open access: yesThe Anatomical Record, EarlyView.
Immunohistochemical staining for tyrosine hydroxylase reveals the neurons forming the locus coeruleus complex in the pontine region of the brain of the Congo gray parrot. The appearance and parcellation of the locus coeruleus complex in birds shows many similarities, but also differences to that observed in mammals.
Pedzisai Mazengenya, Paul R. Manger
wiley   +1 more source

Pheromone gland transcriptome of the pink bollworm moth, Pectinophora gossypiella: Comparison between a laboratory and field population.

open access: yesPLoS ONE, 2019
The pink bollworm, Pectinophora gossypiella, is a world-wide pest of cotton and in some parts of the cotton growing region is controlled by the mating disruption technique using synthetic sex pheromone. The sex pheromone consists of two compounds, (Z,Z)-
Xiaoyi Dou   +4 more
doaj   +1 more source

The MYST histone acetyltransferases are essential for gametophyte development in Arabidopsis

open access: yesBMC Plant Biology, 2008
Background Histone acetyltransferases (HATs) play critical roles in the regulation of chromatin structure and gene expression. Arabidopsis genome contains 12 HAT genes, but the biological functions of many of them are still unknown.
Zhou Dao-Xiu   +6 more
doaj   +1 more source

Histone Acetyltransferases in Plant Development and Plasticity

open access: yesCurrent Genomics, 2014
In eukaryotes, transcriptional regulation is determined by dynamic and reversible chromatin modifications, such as acetylation, methylation, phosphorylation, ubiquitination, glycosylation, that are essential for the processes of DNA replication, DNA ...
Irina Boycheva   +2 more
semanticscholar   +1 more source

Noradrenergic and cholinergic innervation of the normal human heart and changes associated with cardiomyopathy

open access: yesThe Anatomical Record, EarlyView.
Abstract Autonomic nerves are crucial in cardiac function and pathology. However, data on the distribution of cholinergic and noradrenergic nerves in normal and pathologic human hearts is lacking. Nonfailing donor hearts were pressure‐perfusion fixed, imaged, and dissected. Left ventricular cardiomyopathy samples were also obtained.
Peter Hanna   +15 more
wiley   +1 more source

Noncoding RNAs in Host–Microbiota Interaction

open access: yesAnimal Research and One Health, EarlyView.
The intricate interplay between gut microbiota and the host exerts a profound impact on host biological processes and disease development. This review highlights the pivotal role of noncoding RNAs (ncRNAs) in this interaction. Host ncRNAs regulate gene expression and microbiota composition, whereas microbial small RNAs (sRNAs) modulate host gene ...
Ziyi Zhao   +7 more
wiley   +1 more source

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