Results 151 to 160 of about 35,074 (278)

Commensal-derived acetylcholine enhances mucosal immune education. [PDF]

Nature
Song D, Duncan-Lowey B, Khetrapal V, Hamchand R, Deng T, Brown H, Wu A, Martin AL, Bauer KM, Zhao Y, Nguyen MT, Sonnert ND, Leopold SR, Wu Q, Crawford JM, Palm NW.   +15 more
europepmc   +1 more source

ISAba1‐mediated crp‐osmC amplification enhances host‐associated fitness in Acinetobacter baumannii

mLife, EarlyView.
Abstract Acinetobacter baumannii is a pathogen, highly adaptable to both hospital‐ and host‐associated environments. Understanding the genetic mechanisms underlying its adaptability is critical for controlling its persistence. Our study identified the crp‐osmC gene cluster, flanked by ISAba1 elements, as a significant genetic structure undergoing ...
Da‐Wei Wei, Jiangqing Huang, Hailing Fang, Xinyu Wang, Gang Zhang, Chao Wang, Yuqin Song, Jie Feng   +7 more
wiley   +1 more source

Nutriepigenetics in Skin Homeostasis: Molecular Mechanisms of Honey-Mediated Chromatin Remodeling in Non-Healing Ulcers. [PDF]

Biomolecules
Ranzato E, Martinotti S.
europepmc   +1 more source

The epigenetic landscape of plant defense: Unlocking nature's toolkit for new plant protection

New Plant Protection, EarlyView.
This review examines how epigenetic mechanisms regulate plant immune gene activation, repression, and priming, then links these natural regulatory layers to emerging epigenetic editing, discussing their potential for precise, heritable crop protection and the challenges.
Xuexia Liu, Zhenhui Zhong
wiley   +1 more source

Research progress on lysine acetylation (Review). [PDF]

Int J Mol Med
Zhang M, Zhang Y, Yin H, Yan J, Dong Y, Zhao X, Cui T, Lv B, Gao X.   +8 more
europepmc   +1 more source

Aspartic Protease Inhibition Induces Proteomic Remodeling in Paracoccidioides brasiliensis

PROTEOMICS, EarlyView.
ABSTRACT Paracoccidioidomycosis (PCM) is a major systemic mycosis in Latin America caused by Paracoccidioides brasiliensis, yet the contribution of aspartic proteases to fungal physiology and pathogenicity remains poorly understood. Here, we employed data‐independent acquisition (DIA)‐based quantitative proteomics to investigate the impact of pepstatin
Sarah Fernandes Lima, Wilson Dias Segura, Leonardo Brogliato de Moraes, Reinaldo Souza Oliveira, Pedro Henrique Corteletti Manfio, Alison Felipe Alencar Chaves, Wagner Luiz Batista   +6 more
wiley   +1 more source

Traditional Chinese Medicine Intervention Based on Metabolic-Epigenetic Axis: Mechanism and Treatment Strategy of Chronic Heart Failure. [PDF]

Biomolecules
He JC, Wei JM, Wang B, Li RF, Wang W, Li Y.   +5 more
europepmc   +1 more source

Gene turnover in the common ancestor of all C4 grasses

PLANTS, PEOPLE, PLANET, EarlyView.
Understanding how plants evolve more efficient photosynthesis is important in a warming world where improving crop productivity and resilience is a global priority. By generating the first reference genomes for an early‐diverging group of grasses called the Aristidoideae, we were able to reconstruct the genetic makeup of the last common ancestor of all
Lara Pereira, Ahmed S. Alenazi, Sahr Mian, Ilia J. Leitch, Pascal‐Antoine Christin, Colin P. Osborne, Luke T. Dunning   +6 more
wiley   +1 more source

Targeting Histone Acetyltransferases EP300/CBP by Novel Proline-Based PROTAC Degraders. [PDF]

ACS Med Chem Lett
Tan K, Vogt M, Schaal K, Swapna S, Geiger TM, Dressel I, Nowak RP, Bhatia S, Hansen FK.   +8 more
europepmc   +1 more source

Genomics and epigenomics of tissue repair: Implications for personalized medicine

Precision Medical Sciences, EarlyView.
Genomic and epigenomic mechanisms govern tissue repair and regeneration through dynamic regulation of inflammation, cell fate, and extracellular matrix remodeling. The integration of multi‐omics, artificial intelligence, and precision regenerative therapies enables biomarker‐driven, personalized approaches to enhance healing and minimize fibrosis ...
Jharna Medhi, Chandrashekar Thalluri, Sarad Pawar Naik Bukke, Piyali Dey, Mallikarjun Vasam, Ananda Kumar Chettupalli, Swetha Kumari Koduru, Gali Avinash Kumar   +7 more
wiley   +1 more source