Results 171 to 180 of about 91,412 (386)

The kinetic properties of human placental choline acetyltransferase [PDF]

, 1971
David L. Morris, A. Maneckjee, Catherine O. Hebb   +2 more
openalex   +1 more source

Alterations of myocardial ketone metabolism in heart failure with preserved ejection fraction (HFpEF)

ESC Heart Failure, EarlyView.
Abstract Introduction Cardiac energy metabolism is disrupted in heart failure with preserved ejection fraction (HFpEF), as characterized by a switch from glucose oxidation towards fatty acid oxidation. However, although oxidation of ketones is an important source of ATP it remains unclear how the heart oxidizes ketones in HFpEF.
Qiuyu Sun, Cory S. Wagg, Nathan Wong, Kaleigh Wei, Ezra B. Ketema, Liyan Zhang, Liye Fang, John M. Seubert, Gary D. Lopaschuk   +8 more
wiley   +1 more source

The Purification of Choline Acetyltransferase of Squid-Head Ganglia [PDF]

, 1973
S. Shaukat Husain, Henry G. Mautner
openalex   +1 more source

Heart failure and obesity: Translational approaches and therapeutic perspectives. A scientific statement of the Heart Failure Association of the ESC

European Journal of Heart Failure, EarlyView.
Abstract Obesity and heart failure (HF) represent two growing pandemics. In the general population, obesity affects one in eight adults and is linked with an increased risk for HF. Obesity is even more common in patients with HF, where it complicates the diagnosis of HF and is linked with worse symptoms and impaired exercise capacity. Over the past few
Gianluigi Savarese, Gabriele G. Schiattarella, Felix Lindberg, Markus S. Anker, Antoni Bayes‐Genis, Magnus Bäck, Frieder Braunschweig, Chiara Bucciarelli‐Ducci, Javed Butler, Antonio Cannata, Federico Capone, Ovidiu Chioncel, Emilia D'Elia, Arantxa González, Gerasimos Filippatos, Nicolas Girerd, Jean‐Sébastien Hulot, Carolyn S.P. Lam, Lars H. Lund, Christoph Maack, Brenda Moura, Mark C. Petrie, Massimo Piepoli, Abdullah Shehab, Mehmet B. Yilmaz, Peter Seferovic, Carlo G. Tocchetti, Giuseppe M.C. Rosano, Marco Metra   +28 more
wiley   +1 more source

A Novel Role of Cdk9/CyclinT2 complexes in skeletal muscle and Rhabdomyosarcoma cells [PDF]

, 2010
Cyclin dependent kinase 9 (Cdk9) is a member of the cyclin dependent kinase family. The regulatory units of Cdk9 are the T family Cyclins (T1, T2) and Cyclin K1.
Marchesi, Irene
core  

Epigenotoxicity: Decoding the epigenetic imprints of genotoxic agents and their implications for regulatory genetic toxicology

Environmental and Molecular Mutagenesis, EarlyView.
Abstract Regulatory genetic toxicology focuses on DNA damage and subsequent gene mutations. However, genotoxic agents can also affect epigenetic marks, and incorporation of epigenetic data into the regulatory framework may thus enhance the accuracy of risk assessment.
Roger Godschalk, Christopher Faulk, Jessica LaRocca, Jan van Benthem, Francesco Marchetti   +4 more
wiley   +1 more source

Properties of Partially Purified Carnitine Acetyltransferase

, 1963
Irving B. Fritz, Suzzanne K. Schultz, Paul A. Srere   +2 more
openalex   +1 more source

Mitochondria‐Nuclear Crosstalk: Orchestrating mtDNA Maintenance

Environmental and Molecular Mutagenesis, EarlyView.
ABSTRACT The mitochondria (mt) and nucleus engage in a dynamic bidirectional communication to maintain cellular homeostasis, regulating energy production, stress response, and cell fate. Anterograde signaling directs mt function, while retrograde signaling conveys metabolic and stress‐related changes from mt to the nucleus. Central to this crosstalk is
Ghazal Darfarin, Janice Pluth
wiley   +1 more source

Role of Histone acetyltransferase, “p300” in Human Cancer [PDF]

, 2011
p300 is a Histone acetyltransferase which functions as global transcriptional coactivator which plays important roles in various biological processes including cell proliferation, differentiation, and apoptosis.
Rajgandha, Susanta Kumar
core  

The Distribution of Carnitine, Acetylcarnitine, and Carnitine Acetyltransferase in Rat Tissues

, 1965
Norman R. Marquis, Irving B. Fritz
openalex   +1 more source