Multiple forms of choline acetyltransferase in several species demonstrated by isoelectric focusing [PDF]
D. Malthe‐Sørenssen, Frode Fonnum
openalex +1 more source
Abstract Background N‐acetyltransferase 10 (NAT10) was reported to be associated with the immune microenvironment in several cancers. However, it is not known in pancreatic ductal adenocarcinoma (PDAC). This study aimed to elucidate the roles and mechanisms of NAT10 in tumor malignancy and the tumor microenvironment (TME) in PDAC.
Enhong Chen+11 more
wiley +1 more source
Enzymatic Modification of Aminoglycoside Antibiotics: 3- N -Acetyltransferase with Broad Specificity that Determines Resistance to the Novel Aminoglycoside Apramycin [PDF]
Julian Davies, Sean O'Connor
openalex +1 more source
Combining bacterially inactivated antibiotics with antibacterial essential oils (EOs) is an alternative combinatorial therapy against antibiotic‐resistant bacteria, as EOs can also modulate resistance. Apart from the rehabilitation of the antibiotic, this combination is probably more difficult to overcome evolutionarily due to the antibacterial mixture
Rafael Torres‐Martínez+5 more
wiley +1 more source
The kinetic properties of human placental choline acetyltransferase [PDF]
David L. Morris+2 more
openalex +1 more source
5‐thiohistidine N‐acetyltransferase from Proteiniphilum saccharofermentans
Ovothiol A is a 5‐thiohistidine derivative biosynthesized by a broad range of prokaryotic and eukaryotic organisms. Its redox‐active mercaptoimidazole side chain is believed to protect cells from oxidative stress. The three enzymes that produce ovothiol A from histidine, cysteine, and S‐adenosyl methionine have been identified and characterized.
Cangsong Liao+3 more
wiley +1 more source
The Purification of Choline Acetyltransferase of Squid-Head Ganglia [PDF]
S. Shaukat Husain, Henry G. Mautner
openalex +1 more source
A Tailored Phospho‐p53 Library Probes Antibody Specificity and Recognition Limitations
Site‐specifically phosphorylated isoforms of the tumor suppressor p53 – encompassing all seven known phosphorylation sites within the TAD1 domain –are created upon optimization of semisynthesis protocols. This “designer" p53 library enabled validation of phosphorylation‐specific p53 antibodies and revealed epitope masking by phosphorylation in commonly
Mateusz Hess+6 more
wiley +1 more source
In Vivo Biosynthesis and Direct Incorporation of Non‐Canonical Amino Acids into Proteins
Autonomous cells are engineered biological systems capable of biosynthesising and directly incorporating non‐canonical amino acids (ncAAs) into proteins. These systems have the potential to extend the applicability of the genetic code to enable large‐scale fermentative production of proteins carrying ncAAs.
Ivana Drienovska+2 more
wiley +1 more source
Co-translational, Post-translational, and Non-catalytic Roles of N-Terminal Acetyltransferases.
Henriette Aksnes, Rasmus Ree, T. Arnesen
semanticscholar +1 more source