Results 101 to 110 of about 2,718,252 (313)

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

Evaluating German PISA stratification designs: a simulation study

open access: yesLarge-scale Assessments in Education
Stratification is an important design feature of many studies using complex sampling designs and it is often used in large-scale assessment (LSA) studies, such as the Programme for International Student Assessment (PISA), for two main reasons.
Julia Mang   +2 more
doaj   +1 more source

The Social Validity of Video Modeling Versus Virtual Reality for Improving the Social Communication Skills of Middle School Students

open access: yesIssues and Trends in Learning Technologies
The extent to which an intervention is perceived as sociallyvalid significantly influences whether the intervention is selected,implemented, and maintained (Kern & Manz, 2004).
Adam C Carreon   +9 more
doaj   +2 more sources

RELATIONSHIP BETWEEN LEARNING MOTIVATION INTRINSIC AND EXTRINSIC STUDENTS WITH LEARNING STUDENT ACHIEVEMENT X CLASS VIDEO AUDIO ENGINEERING SKILLS COMPETENCY SMK MA'ARIF 1 WATES [PDF]

open access: yes, 2012
This study aimed to determine whether there is a relationship between intrinsic and extrinsic motivation students individually or jointly with a class X student achievement competency skills SMK Techniques Audio Video Ma'arif 1 Wates.
Vreedy, Frans Danar
core  

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

The Competition Account of Achievement‐Value [PDF]

open access: yes, 2019
A great achievement makes one’s life go better independently of its results, but what makes an achievement great? A simple answer is—its difficulty.
Dunkle, Ian D.
core  

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Undergraduate Achievement Disparities between Demographic Subgroups in English Universities

open access: yesTrends in Higher Education
In this paper, we report a comprehensive analysis of the disparities in undergraduate degree achievements across different demographic groups in English universities.
Pallavi Banerjee, Nurullah Eryilmaz
doaj   +1 more source

Achievement for all: leadership matters [PDF]

open access: yes, 2011
Purpose: "The focus of this document is on leadership - the impact that effective leaders have on their schools and their pupils; and the impact that the project has had upon the leadership styles and strategies within participating schools. It aims to:

core  

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