Results 131 to 140 of about 176,254 (281)

Recent developments in Achilles tendon risk-analyzing rupture factors for enhanced injury prevention and clinical guidance: Current implications of regenerative medicine

Journal of Orthopaedic Translation
Background: In recent years, many countries have actively implemented programs and strategies to promote physical education and sports. Despite these efforts, the increase in physical activity has been accompanied by a significant rise in muscle and ...
Maria V. Sankova, Narasimha M. Beeraka, Marine V. Oganesyan, Negoriya A. Rizaeva, Aleksey V. Sankov, Olga S. Shelestova, Kirill V. Bulygin, Hemanth Vikram PR, A.N. Barinov, A.K. Khalimova, Y. Padmanabha Reddy, Basappa Basappa, Vladimir N. Nikolenko   +12 more
doaj   +1 more source

Genetic Predictors of Progression and Skin Rash in Japanese mCSPC Patients Treated With Apalutamide: CUARTET Study

Cancer Science, EarlyView.
In patients with mCSPC treated with apalutamide plus ADT, baseline ctDNA predicted earlier progression to CRPC and worse overall survival. Exploratory genome‐wide analysis identified 12 SNPs associated with apalutamide‐related skin rash. ABSTRACT Despite promising evidence of the efficacy of the androgen deprivation therapy (ADT) plus apalutamide in ...
Masaki Shiota, Taku Naiki, Koji Hatano, Akira Yokomizo, Hiroaki Tsuchiya, Yoko Takahashi, Taku Nakayama, Masaki Yoshida, Hirotsugu Uemura   +8 more
wiley   +1 more source

Physiological Basis of Sex Differences in Human Performance and Exercise‐Associated Pathology

Clinical Endocrinology, EarlyView.
ABSTRACT The presence of sex differences in human physical performance is well‐established and shaped by distinct endocrine, anatomical and physiological mechanisms. Despite sustained advances, our understanding of how inherent biological factors drive variations in exercise capacity and related pathologies is still developing.
David A. Holdsworth, Thomas J. O'Leary, Craig L. Doig, Natalie Taylor, Jasminder Dosanjh, David R. Woods, Michael J. Stacey, Robert M. Gifford   +7 more
wiley   +1 more source

Real‐Time Conformal Maps and Parameterizations

Computer Graphics Forum, EarlyView.
Abstract We present a simple algorithm to conformally map between two simple and bounded planar domains based on the concept of harmonic measure, which is a conformal invariant. With suitable preprocessing, the algorithm is fast enough to compute all possible conformal maps (having three real degrees of freedom) between the two domains in real time in
Q. Chang, C. Gotsman, K. Hormann
wiley   +1 more source

Interstitial 11q Deletions and Terminal 11q Duplications Cause a Bleeding Tendency due to Platelet Dysfunction That Is Similar to 11q Deletions Causing Jacobsen Syndrome

European Journal of Haematology, EarlyView.
ABSTRACT Introduction Jacobsen syndrome, resulting from a terminal deletion of chromosome 11 (11q), may lead to an increased bleeding tendency due to low platelet counts or platelet dysfunction. Currently, information on bleeding tendency and platelet function in patients with nonterminal 11q‐aberrations such as larger deletions, interstitial 11q ...
Elise J. Huisman, Virgil A. S. H. Dalm, Marieke Joosten, Frans J. Smiers, Leendert Porcelijn, Arjan Hoogendijk, Hans Janssen, Nicole N. van der van der Wel, Idske C. L. Kremer Hovinga, Masja de Haas, Marjon H. Cnossen   +10 more
wiley   +1 more source

The Master's Problem: Revisiting Hegel's Critique of Social Domination

European Journal of Philosophy, EarlyView.
Abstract This paper argues for a reinterpretation of Hegel's internal critique of the master in his famous ‘Master–Slave Dialectic.’ Hegel argues that, in addition to the evident injustice suffered by the enslaved, the arrangement also undermines the master's own purposes.
Stephen Cunniff
wiley   +1 more source

Aristocratic identification in Felix’s Life of Guthlac

Early Medieval Europe, EarlyView.
Recent scholarship often sees high‐born monastics and clerics in early Christian England as part of the aristocratic class. Modern identity theories, however, suggest that social identity could be dynamic, situational, processual and discursive. In light of this concept, the present article reads Felix’s Life of Guthlac as a text that constructs an ...
Lek Hang Chan
wiley   +1 more source

Compromised DNA replication in gut cells underlies sensitivity to genotoxic stress in the tardigrade Hypsibius exemplaris

The FEBS Journal, EarlyView.
DNA damage in the tardigrade Hypsibius exemplaris elicits distinct cellular outcomes depending on replication status. While non‐replicating cells tolerate genotoxic stress, constitutively replicating cells undergo irreversible replication failure upon DNA damage, leading to loss of tissue homeostasis, fat depletion, sterility, and organismal death ...
Gonzalo Quiroga‐Artigas, Pauline Fontanié, Benjamin Lacroix, Maria Dolores Molina, María Moriel‐Carretero   +4 more
wiley   +1 more source

Pancreatic Cancer—Advances in the Last 50 Years

World Journal of Surgery, EarlyView.
S. George Barreto, Anirban Maitra, Eileen M. O'Reilly, Dushyant Sahani, Richard Zheng, Charles J. Yeo   +5 more
wiley   +1 more source

Plantar fascia thickness in type 1 diabetes mellitus patients: Clinical associations and metabolic correlates

Journal of Diabetes Investigation, EarlyView.
Ultrasound‐measured plantar fascia thickness is associated with microvascular complications and glycemic control in individuals with type 1 diabetes, suggesting PFT as a potential non‐invasive tool for clinical assessment. In addition, improved thickness values were observed in patients using automated insulin delivery systems.
Giulia Casadei, Michele Baldari, Lorenzo Brognara, Enrico Saudelli, Simona Moscatiello, Sara Flamigni, Francesco Traina, Alexandro Paccapelo, Uberto Pagotto, Guido Di Dalmazi   +9 more
wiley   +1 more source