Results 1 to 10 of about 4,585 (189)

A randomised controlled trial of the use of aciclovir and/or prednisolone for the early treatment of Bell’s palsy: the BELLS study

Health Technology Assessment, 2009
Objective: To determine whether oral prednisolone or aciclovir, used separately or in combination, early in the course of Bell’s palsy, improves the chances of recovery at 3 and 9 months. Design: A 2 × 2 factorial randomised double-blind trial.
FM Sullivan, IRC Swan, PT Donnan, JM Morrison, BH Smith, B McKinstry, RJ Davenport, LD Vale, JE Clarkson, R Hernández, K Stewart, V Hammersley, S Hayavi, A McAteer, D Gray, F Daly   +15 more
doaj   +2 more sources

Aciclovir: nuevo antiviral

ARS Medica, 2017
El aciclovir es un antiviral útil en infecciones graves causadas por el virus varicela-zoster. Es bien tolerado con escasas reacciones adversas. En pacientes deshidratados, en insuficiencia renal o si la infusión endovenosa es muy rápida, puede ocacionar
G. Repetto
doaj   +3 more sources

A UHPLC–MS/MS Method for Therapeutic Drug Monitoring of Aciclovir and Ganciclovir in Plasma and Dried Plasma Spots

Biomedicines, 2021
The role of therapeutic drug monitoring (TDM) of valaciclovir (VA)/aciclovir (A) and valganciclovir/ganciclovir (VG/G) in critically ill patients is still a matter of debate.
Raffaele Simeoli, Sebastiano Barco, Alberto Magnasco   +2 more
exaly   +3 more sources

Evaluating valaciclovir, letermovir, and maribavir safety in first-trimester human placental development [PDF]

Scientific Reports
Congenital cytomegalovirus (CMV) infection is the leading preventable cause of childhood disability, including sensorineural hearing loss and cerebral palsy in high-income countries.
Ishara Atukorala, Natasha de Alwis, Sally Beard, Swetha Raghavan, Natalie J. Hannan, Lisa Hui   +5 more
doaj   +2 more sources

Full recovery of a 13-year-old boy with pediatric Ramsay Hunt syndrome using a shorter course of aciclovir and steroid at lower doses: a case report [PDF]

Journal of Medical Case Reports, 2011
Introduction Reports on children with Ramsay Hunt syndrome are limited in the literature, resulting in uncertainty regarding the clinical manifestations and outcome of this syndrome. Treatment for Ramsay Hunt syndrome is usually with antivirals, although
Chibwowa Sheenah, Masukume Gwinyai, Ndlovu Mbongeni   +2 more
doaj   +2 more sources

Kanuka honey versus aciclovir for the topical treatment of herpes simplex labialis: a randomised controlled trial

BMJ Open, 2019
Objective To compare New Zealand medical grade kanuka honey with topical aciclovir for the treatment of herpes simplex labialis.Design Prospective parallel randomised controlled open-label superiority trial.Setting 76 community pharmacies across New ...
Alex Semprini, Irene Braithwaite, Darmiga Thayabaran   +2 more
exaly   +3 more sources

Population pharmacokinetics and dose rationale for aciclovir in term and pre‐term neonates with herpes [PDF]

Pharmacology Research & Perspectives
Aciclovir is considered the first‐line treatment against Herpes simplex virus (HSV) infections in new‐borns and infants. As renal excretion is the major route of elimination, in renally‐impaired patients, aciclovir doses are adjusted according to the ...
S. D'Agate, D. Ruiz Gabarre, O. Della Pasqua   +2 more
doaj   +2 more sources

Recuperación de parálisis facial idiopática: ¿Prednisolona o prednisolona/aciclovir?

Repertorio de Medicina y Cirugía, 2010
En la literatura hay discrepancia acerca del tratamiento de la parálisis facial idiopática. No existe suficiente evidencia que soporte la asociación de un antiviral con corticoide sistémico; sin embargo, su uso es frecuente en la práctica clínica ...
María Angélica Amaya, Gustavo Romero, Jorge Luis Herrera   +2 more
doaj   +3 more sources

Impact of aciclovir on genital and plasma HIV-1 RNA in HSV-2/HIV-1 co-infected women: a randomized placebo-controlled trial in South Africa

Aids, 2009
Jerome LeGoff, Helen V Rees, Philippe Mayaud   +2 more
exaly   +3 more sources

Stewardship: it's going viral [PDF]

Infection Prevention in Practice
Summary: Introduction: Historically, antimicrobial stewardship (AMS) has considered the judicious use of antibiotics. AMS is widely adopted across Europe and the US; recently antifungal AMS is gaining momentum but antiviral AMS has been little described.
Abigail Jenkins, Jubeyr Ahmed, Andrew Bosworth, I Michael Kidd, Husam Osman, Sowsan F. Atabani   +5 more
doaj   +2 more sources