Results 101 to 110 of about 1,551,879 (383)

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

EXTRAÇÃO DO CORANTE DA BETERRABA (BETA VULGARIS) PARA UTILIZAÇÃO COMO INDICADOR ÁCIDO-BASE

Eclética Química, 2018
In this study, we investigated the behavior of aqueous and alcoholic extract of sugar beet (Beta vulgaris) as an acid-base indicator, having as main objective the awakening interest in the  use of natural indicators as an alternative to teaching of ...
Ariela Suzan Cuchinski, Josiane Caetano, Douglas Cardoso Dragunski   +2 more
doaj   +1 more source

Bimodal Distribution of Sulfuric Acid Aerosols in the Upper Haze of Venus [PDF]

, 2013
The upper haze (UH) of Venus is variable on the order of days and it is populated by two particle modes. We use a 1D microphysics and vertical transport model based on the Community Aerosol and Radiation Model for Atmospheres to evaluate whether ...
Bardeen, Charles G., Crisp, David, Gao, Peter, Yung, Yuk L., Zhang, Xi   +4 more
core   +2 more sources

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

STUDY OF ELECTROCHEMICAL BEHAVIOR OF VI-B GROUP METAL OXIDES IN TUNGSTATE MELT

Studia Universitatis Babes-Bolyai Chemia
Thermodynamic assessment of the probability of interaction of metal oxides of group VI-B with tungstate melts, the results of the study of the acid-base properties of tungstate melt by potentiometric method.
Victor MALYSHEV, Angelina GAB, Ana-Maria POPESCU, Virgil CONSTANTIN   +3 more
doaj   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Evidence of nitric acid uptake in warm cirrus anvil clouds during the NASA TC4 campaign [PDF]

, 2010
Uptake of HNO3 onto cirrus ice may play an important role in tropospheric NOx cycling. Discrepancies between modeled and in situ measurements of gas-phase HNO3 in the troposphere suggest that redistribution and removal mechanisms by cirrus ice have been ...
Bansemer, Aaron, Dibb, Jack E., Heymsfield, Andrew J, Rogers, David, Scheuer, Eric, Twohy, Cynthia   +5 more
core   +2 more sources

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

FEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

S, Zn, Cr, Cu and Fe changes during fluvial sediments oxidation [PDF]

Ciencia del Suelo, 2009
Acidification of dredged sediments which have been disposed on land is highly dependent on redox shifts. The aim of the present work was to assess changes in sulphur, metal speciation (Zn, Fe, Cr y Cu) and acidity caused by a polluted sediment oxidation ...
María Pía Di Nanno, Gustavo Curutchet, Silvia E Ratto   +2 more
doaj  

The Effect of an Acidic Food-Simulating Environment on the Shear Bond Strength of Self-Ligating Brackets with Different Base Designs

International Journal of Dentistry, 2014
Aim. This study aims to evaluate the effect of acidic food simulant and (acetic acid 3%) on the shear bond strength (SBS) and adhesive remnant index (ARI) scores of one conventional and three different self-ligating brackets with different base designs ...
Ahmad Sheibaninia, Sepehr Sepasi, Mohammad Ali Saghiri, Setareh Sepasi   +3 more
doaj   +1 more source