Results 61 to 70 of about 59,217 (252)

Perioperative care in pediatric OTC deficiency and goldenhar syndrome: a case report

Frontiers in Pediatrics
Ornithine transcarbamylase deficiency (OTCD) is an X-linked disorder disrupting the urea cycle in 1 per 56,000 births. Goldenhar syndrome (GS), characterized by craniofacial and vertebral anomalies, is seen in 1 per 3,000–5,000 births.
Daniela Torres Salazar, Daniela Torres Salazar, Andres Felipe Beltran, Andres Felipe Beltran, Sergio Alzate-Ricaurte, Sergio Alzate-Ricaurte   +5 more
doaj   +1 more source

ELECTROLYTES – SODIUM, POTASSIUM AND CHLORIDES IN POULTRY NUTRITION

Archives of Veterinary Medicine, 2016
Sodium, potassium and chlorides play a crucial role in maintaining body acid-base balance as well as osmotic pressure in body fluids. These processes are the result of synergetic action of all three elements, and the role of each individual component is ...
Milica Živkov Baloš, Sandra Jakšić, Slobodan Knežević, Miloš Kapetanov   +3 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Study on biochemical findings and status of acid-base disorder among the patients attending Nobel Medical College Teaching Hospital.

Journal of Nepal Medical Association, 2019
Introduction: Acid base disorder is a condition characterized by alteration in blood pH by the imbalance between the components of blood leading to a life threatening situation.
Rupesh Kumar Shreewastav, Krishna Pokhrel, Madan Pandey, Ganesh Prasad Singh, Arambam Giridhari Singh   +4 more
doaj   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Multiple electrolyte imbalances and mixed acid-base disorder posing a diagnostic dilemma: a case report

Journal of Medical Case Reports, 2020
Background In clinical practice, both the history and laboratory testing are paramount to making an accurate diagnosis. Situations in which laboratory findings and patient history are not congruent pose a diagnostic dilemma.
Fortune O. Alabi, Christopher O. Alabi, Rafaela G. Basso, Nadia Lakhdar, Adebanke O. Oderinde   +4 more
doaj   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

Comparison of low-cost interventions for pain during radial arterial blood gas sampling in the emergency department: a three-arm randomised controlled trial

Emergency Care Journal
This study evaluated the efficacy of topical anaesthesia and cryo-analgesia for pain management during radial Arterial Blood Gas (ABG) sampling, compared with standard care.  An open-label, randomised controlled trial with blinded statistical analysis in
Chawin Taveekijakarn, Tuntanut Lohawatcharagul, Supichaya Vitoonpanakoon, Pornchanok Sirisantisamrid, Thanathip Suenghataiphorn, Peerada Valyasevi, Ponphisudti Tangsirisatian   +6 more
doaj   +1 more source

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

FEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa, Kazuhiko Higashida, Naoya Nakai   +2 more
wiley   +1 more source