Results 81 to 90 of about 1,392,835 (305)
Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity
FEBS Open Bio, EarlyView.Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz +9 more
wiley +1 more source
ELECTROLYTES – SODIUM, POTASSIUM AND CHLORIDES IN POULTRY NUTRITION
Archives of Veterinary Medicine, 2016 Sodium, potassium and chlorides play a crucial role in maintaining body acid-base balance as well as osmotic pressure in body fluids. These processes are the result of synergetic action of all three elements, and the role of each individual component is ...
Milica Živkov Baloš +3 more
doaj +1 more source
Metabotropic glutamate 2/3 receptors and epigenetic modifications in psychotic disorders: a review [PDF]
, 2016 Schizophrenia and Bipolar Disorder are chronic psychiatric disorders, both considered as "major psychosis"; they are thought to share some pathogenetic factors involving a dysfunctional gene x environment interaction.
Grayson, Danis R +4 more
core +2 more sources
FEBS Open Bio, EarlyView.Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid +3 more
wiley +1 more source
Risk factors for mortality in patients with acute exacerbation of cor pulmonale in plateau
BMC Pulmonary Medicine, 2023 Background The risk factors for mortality might differ between patients with acute exacerbation of chronic pulmonary heart disease in plains and plateaus, while there is a lack of evidence.
Xiaokai Feng +6 more
doaj +1 more source
Gastric Outlet Obstruction Due to Peptic Ulcer Disease [PDF]
, 2011 Gastric outlet obstruction is a rare complication of peptic ulcer disease, resulting from acute or chronic inflammatory changes. Patient may present asymptomatic or may have mild gastrointestinal symptoms. Some complications may include indirect systemic
Fauzi, A. (Achmad), Sejati, A. (Arif)
core +1 more source
FEBS Open Bio, EarlyView.Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu +5 more
wiley +1 more source
Perioperative care in pediatric OTC deficiency and goldenhar syndrome: a case report
Frontiers in PediatricsOrnithine transcarbamylase deficiency (OTCD) is an X-linked disorder disrupting the urea cycle in 1 per 56,000 births. Goldenhar syndrome (GS), characterized by craniofacial and vertebral anomalies, is seen in 1 per 3,000–5,000 births.
Daniela Torres Salazar +5 more
doaj +1 more source
Journal of Nepal Medical Association, 2019 Introduction: Acid base disorder is a condition characterized by alteration in blood pH by the imbalance between the components of blood leading to a life threatening situation.
Rupesh Kumar Shreewastav +4 more
doaj +1 more source
Journal of Medical Case Reports, 2020 Background In clinical practice, both the history and laboratory testing are paramount to making an accurate diagnosis. Situations in which laboratory findings and patient history are not congruent pose a diagnostic dilemma.
Fortune O. Alabi +4 more
doaj +1 more source