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Acid Dissociation Constants of Phenylalkanolamines

Journal of Pharmaceutical Sciences, 1962
The acid dissociation constants of phenylephrine, synephrine, and tyramine were investigated by the new spectrophotometric method of Edsall. Epinephrine was studied by a titration and complexation method. It is concluded from analysis of the spectral data that the phenolic function is a stronger acid than the alkylammonium group.
S, RIEGELMAN, L A, STRAIT, E Z, FISCHER
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Dissociation constants of carboxymethyloxysuccinic acid

Talanta, 1974
The dissociation constants of carboxymethyloxysuccinic acid (CMOS) have been measured at 25 degrees and an ionic strength of 0.1M in sodium perchlorate. The values found were: pK(1) = 2.52, pK(2) = 3.77 and pK(3) = 5.00. CMOS is thus seen to be rather stronger than its isomer citric acid.
C E, Rodriguez, C D, Devine
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Dissociation constants of organophosphinic acid compounds

Talanta, 1993
The dissociation equilibria of di(2,4,4-trimethylpentyi) phosphinic acid, mono(2,4,4-trimethylpentyl) phosphinic acid, di(n-octyl)phosphinic acid and mono(n-octyl)phosphinic acid have been studied in ethanol-water mixtures by potentiometric titration at 25 degrees C.
M, Martinez   +3 more
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The acid dissociation constants of 2,3-quinoxalinedithiol

Talanta, 1972
Sodium salts of 2,3-quinoxalinedithiol have been prepared and used for determination of the acid ionization constants by potentiometric titration. The fully protonated form of the reagent was used in an alternative determination of the first ionization constant by a solubility method. The constants are pK(2), == 6.84 +/- 0.04 and pK(2) = 9.95 +/- 0.03.
J A, Dalziel, A K, Slawinski
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Dissociation Constants of Carboxylic Acids in Formamide

Nature, 1960
IT has already been shown1,2 that the dissociation constants Ka of formic and acetic acid are lower in formamide than in water although the dielectric constant of the former is much larger than that of the latter. The variation of Ka with temperature may, in both solvents, be described by a reduced curve proposed by Earned and Embree3:
Mandel, Michel, Decroly, Pierre Victor
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Dissociation constants of perfluoroalkanoic acids

Monatshefte für Chemie - Chemical Monthly, 2017
The dissociation constants of six selected perfluoroalkanoic acids (from perfluoropentanoic to perfluorodecanoic acid) were determined using neutralization potentiometric titration method. The values of determined dissociation constants ranges from pK a = 2.17 to 2.44, and they are in partial agreement with published data ...
Radomír Čabala   +2 more
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