Results 151 to 160 of about 40,009 (268)

Diarylamidines: high potency inhibitors of acid-sensing ion channels

, 2010
Acid-sensing ion channels (ASICs) are proton-gated cation channels that are predominantly expressed in the nervous system. ASICs are involved in a number of neurological diseases such as pain, ischemic stroke and multiple sclerosis but limited tools are ...
Chen, Xuanmao, Dürrnagel, Stefan Johannes, Orser, Beverley A., Xiong, Zhi-Gang, Li, Minghua, MacDonald, John F., Qiu, Liyan, Grunder, Stefan   +7 more
core   +1 more source

Inhibition of Acid-Sensing Ion Channels by KB-R7943, a Reverse Na⁺/Ca²⁺ Exchanger Inhibitor. [PDF]

Biomolecules, 2023
Sun HW, Chu XP, Simon RP, Xiong ZG, Leng TD.   +4 more
europepmc   +1 more source

Transfer Printing and Reconfiguration of Soft Electronics Using Digital Microfluidics and Laser Machining

Advanced Functional Materials, EarlyView.
This paper presents a digital microfluidics‐based technique for transferring and reconfiguring soft nanomembranes. Laser‐machined nanothin membranes are picked up, transported, and aligned via tailored surface tension and the actuation of water droplets, enabling the development of flexible electronics, the integration of functional materials on 3D ...
Quang Anh Nguyen, Chi Cong Nguyen, Tran Bach Dang, Phuoc Thien Phan, Jordan Thorpe, Michael Listyawan, Nhat Minh Doan, Sinuo Zhao, Hongru Chen, Trung Thien Hoang, Mingsheng Xu, Jisheng Han, Thanh Nho Do, Adam Hill, Timothée Mouterde, Hoang‐Phuong Phan   +15 more
wiley   +1 more source

Data from: Acid-sensing ion channels emerged over 600 MYA and are conserved throughout the deuterostomes

, 2018
Acid-sensing ion channels (ASICs) are proton-gated ion channels broadly expressed in the vertebrate nervous system, converting decreased extracellular pH into excitatory sodium current.
Pless, Stephan A., Colding, Janne M, Colding, Janne M., Glover, Joel C, Mikhaleva, Yana, Lynagh, Timothy, Pless, Stephan A, Glover, Joel C.   +7 more
core   +1 more source

Dipole‐Engineered Conductive Additives for Ultrastable Interphase Evolution in High‐Areal‐Capacity Silicon Anodes

Advanced Functional Materials, EarlyView.
In the work reported herein, dipole‐engineered sulfonated carbon nanofibers enable conductive additives to actively regulate interphase formation in silicon anodes. Polar sulfonyl groups guide electrolyte decomposition to form a compact LiF‐rich interphase while promoting robust integration with silicon.
Song Kyu Kang, Hyeonju Kim, Jeongbin Cho, Minseon Park, Taehun Kim, Seonghun Sin, Won Bae Kim   +6 more
wiley   +1 more source

Novel conorfamides from Conus austini venom modulate both nicotinic acetylcholine receptors and acid-sensing ion channels

, 2019
Conorfamides are a poorly studied family of cone snail venom peptides with broad biological activities, including inhibition of NMDA receptors, acid-sensing ion channels, voltage-gated potassium channels, and ligand-gated glutamate receptors.
Lewis, Richard J., Alewood, Paul F., Jin, Ai-hua, Rash, Lachlan D., Espinosa, Roberto Arreguín, Román González, Sergio Agustín, Vetter, Irina, Cristofori-Armstrong, Ben   +7 more
core   +1 more source

Resolving the Cu(bdc) Conundrum: Identifying Non‐Porous Packing of Prototypical Coordination‐Network Thin Films Combining Advanced Diffraction Techniques and Computational Modelling

Advanced Functional Materials, EarlyView.
Solution‐processed Cu(bdc) forms prototypical MOF thin films for which a multitude of not fully satisfactory structural models have been suggested. Combining rotating grazing‐incidence diffraction and X‐ray reflectivity on two complementary samples with density‐functional theory, we first discard the previously suggested models and then identify a non ...
Narges Taghizade, Mario Fratschko, Robbin Steentjes, Mercedes Linares‐Moreau, Paolo Falcaro, Christof Wöll, Roland Resel, Egbert Zojer   +7 more
wiley   +1 more source

Regulation of acid-sensing ion channels by protein binding partners. [PDF]

Channels (Austin), 2021
Cullinan MM, Klipp RC, Bankston JR.
europepmc   +1 more source

Pull‐and‐Push Nanotherapeutic Hydrogels: Scavenging Inflammatory Triggers While Driving Tissue Regeneration in Burn Wounds

Advanced Functional Materials, EarlyView.
A nanounit‐assembled hydrogel employing a “pull‐and‐push” strategy simultaneously scavenges pro‐inflammatory cell‐free DNA (cfDNA) and delivers regenerative therapeutics in response to burn‐induced hyperthermia. By repolarizing macrophages and promoting angiogenesis, this multifunctional platform accelerates burn wound healing, offering a blueprint for
Han‐Sem Kim, Seong‐Jin Shin, Sak Lee, Nandin Mandakhbayar, Ji‐Hye Kang, Da‐Young Kong, Seong‐Doo Hong, Ueon Sang Shin, Hae‐Won Kim, Jung‐Hwan Lee   +9 more
wiley   +1 more source

Peripheral and central mechanisms in acid induced visceral pain hypersensitivity in the human oesophagus

, 2010
PhDIntroduction: Gastro-oesophageal reflux disease (GORD) affects 40% of Western populations. Many symptoms persist despite the resolution of inflammation or acid exposure.
Chua, Yang Chong
core