Results 101 to 110 of about 2,018,257 (280)

Evaluation of Some Quality Parameters of Pumpkin Seeds and Oil After Roasting with Marjoram

open access: yesFoods
Consumers include pumpkin seeds in their diet as a snack in raw form or minimally processed by roasting. This process enables the seeds to develop a characteristic aroma and color. Herbs and spices are also distinguished by a pleasant and delicate aroma.
Mariola Kozłowska   +6 more
doaj   +1 more source

Plasma lipidomic and metabolomic profiles in high‐grade glioma patients before and after 72‐h presurgery water‐only fasting

open access: yesMolecular Oncology, EarlyView.
Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé   +7 more
wiley   +1 more source

Approaches to Assessing the Quality of Fatty Oils and Medicinal Products Formulated as Oily Solutions

open access: yesРегуляторные исследования и экспертиза лекарственных средств
INTRODUCTION. Vegetable fatty oils can comprise over 50% of a medicinal product formulated as an oily solution (in some cases, 100%). The quality of the vegetable fatty oil used and the processes occurring in this oil have a significant impact on the ...
A. A. Ponomarenko, L. I. Panova
doaj   +1 more source

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini   +10 more
wiley   +1 more source

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan   +10 more
wiley   +1 more source

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

open access: yesMolecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka   +10 more
wiley   +1 more source

Effects of Extraction Process Parameters on the Quality Characteristics of Parinari Polyandra B. Seed Oil

open access: yesNigerian Journal of Technological Development, 2016
Extraction process parameters can influence the quality of oil obtained from seeds during extraction process. The effect of extraction process parameters on the quality of parinari seed oil, a potential renewable industrial raw material, is yet to be ...
T. E. Odetoye   +2 more
doaj  

Home - About - Disclaimer - Privacy