Results 101 to 110 of about 4,240,501 (304)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Preparation of polyimides from mixtures of monomeric diamines and esters of polycarboxylic acids [PDF]

open access: yes, 1973
Polyimides having high thermal and oxidative stability are prepared by the reaction of a mixture of monomers comprising (1) a dialkyl or tetraalkyl ester of an aromatic tetracarboxylic acid; (2) an aromatic diamine; and (3) a monoalkyl or dialkyl ester ...
Delvigs, P.   +2 more
core   +1 more source

Fluctuations of Complex Networks: Electrical Properties of Single Protein Nanodevices

open access: yes, 2004
We present for the first time a complex network approach to the study of the electrical properties of single protein devices. In particular, we consider an electronic nanobiosensor based on a G-protein coupled receptor.
Akimov, V.   +4 more
core   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

High-Oleic Sunflower Oil as a Potential Substitute for Palm Oil in Sugar Coatings—A Comparative Quality Determination Using Multispectral Imaging and an Electronic Nose

open access: yesFoods
Palm oil has a bad reputation due to the exploitation of farmers and the destruction of endangered animal habitats. Therefore, many consumers wish to avoid the use of palm oil.
Nicole Ollinger   +7 more
doaj   +1 more source

One pot solvothermal synthesis of organic acid coated magnetic iron oxide nanoparticles [PDF]

open access: yes, 2013
Indexación: ScieloABSTRACT In this work we present the synthesis and characterization of iron oxide nanoparticles (IONPs), which were structurally and magnetically characterized. The use of iron salts and an organic acid (l-serine or ascorbic acid) as
Cruz, Carlos   +4 more
core  

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