Results 71 to 80 of about 196,806 (297)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
FEBS Letters, EarlyView.The pyruvate generator, which causes activation of respiration by extra‐mitochondrial Ca2+, is also present and functional in rat brainstem mitochondria, as it is in other brain regions. This finding is confirmed by experiments with a fully reconstituted malate–aspartate shuttle (MAS).
Grazyna Debska‐Vielhaber +7 more
wiley +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Microbial oxidation of Fe21 and pyrite exposed to flux of micromolar H2O2 in acidic media [PDF]
, 2013 At an initial pH of 2, while abiotic oxidation of aqueous Fe21 was enhanced by a flux of H2O2 at micromolarconcentrations, bio-oxidation of aqueous Fe21 could be impeded due to oxidative stress/damage inAcidithiobacillus ferrooxidans caused by Fenton ...
Lin, C, Ma, Yingqun, Ma, Y, Lin, Chuxia
core +1 more source
Sakarya Üniversitesi Fen Bilimleri Enstitüsü Dergisi, 2019 Graphiteelectrode was modified by polypyrrole (PPy) thin film. PPy was electrodepositedpotentiostatically by applying -1.5 V from acidic aqueous solution havingpyrrole monomers.
Abdulcabbar Yavuz +2 more
doaj +1 more source
Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes
FEBS Letters, EarlyView.Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez +2 more
wiley +1 more source
The anodic dissolution of covellite in acidic, chloride solutions
, 2010 An electrochemical study was conducted on a stationary, synthetically produced, covellite electrode in acidic, chloride solutions at ambient conditions to investigate the dissolution behaviour of the mineral over a surface potential range from the open ...
Basson, Petrus
core
Template Syntheses of Porous Silica Adsorbents with Spherical Particle Morphologies
Adsorption Science & Technology, 2006 The peculiarities of template syntheses of ordered porous silicas with spherical particle morphologies were investigated in alkaline and acidic media.
I.S. Berezovska +4 more
doaj +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source