Results 81 to 90 of about 17,547,833 (304)

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

The kinetics of the dissolution of chalcopyrite in chloride media [PDF]

open access: yes, 2009
One of the most important outstanding problems with the hydrometallurgy of copper is the low temperature leaching of chalcopyrite. In this thesis, a fundamental study at low temperature was undertaken in order to establish a mechanism, which is ...
Velásquez Yévenes, Lilian
core  

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

Protonation of citraconic and glutaconic acid in perchloric acid media

open access: yesTechnologica Acta : Scientific/professional journal of chemistry and technology, 2019
The protonation process of citraconic and glutaconic acid in perchloric acid media was followed using the method of UV spectroscopy. The observed changes in the UV spectra of investigated acids confirmed that the protonation process in perchloric acid with concentration from 5 to 10 mol/dm3 occurred.
Jankulovska-Petkovska, Milena   +2 more
openaire   +3 more sources

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Tantalisingly Close: An Archaeology of Communication Desires in Discourses of Mobile Wireless Media [PDF]

open access: yes, 2008
While many studies on mobile wireless communication devices predominantly take a micro-scale approach and concentrate their often ethnographically informed focus on use values, social implications, conversation strategies, changing norms and ethics ...
de Vries, I.O.   +2 more
core   +1 more source

Blood levels of Glial Fibrillary Acidic Protein (GFAP) in patients with neurological diseases [PDF]

open access: yes, 2013
Background and Purpose: The brain-specific astroglial protein GFAP is a blood biomarker candidate indicative of intracerebral hemorrhage in patients with symptoms suspicious of acute stroke.
Niessner, Marion   +11 more
core   +2 more sources

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Media History and Social Regulation Mod 2 Unit 8

open access: yes, 2010
Module 2 discusses key features and developments in media history, focusing on the histories of print and audio-visual media. The module examines issues in the debates that govern scholarly, ethical and political thinking about the actual or desired ...
Department of Media and Communications
core  

South African Media and Politics: Is the Three Models Approach Still Valid After Two Decades? [PDF]

open access: yes
When Hallin and Mancini (2004) produced their watershed Three Models theory, South Africa was a new democracy barely a decade old. Even then, along with other countries of the Global South, the experience of a young democracy posed certain critical ...
Jones, Bernadine, Hadland, Adrian
core   +1 more source

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