Results 101 to 110 of about 65,295 (252)

Natural and Induced Mitochondrial Phosphate Carrier Loss: DIFFERENTIAL DEPENDENCE OF MITOCHONDRIAL METABOLISM AND DYNAMICS AND CELL SURVIVAL ON THE EXTENT OF DEPLETION. [PDF]

, 2016
The relevance of mitochondrial phosphate carrier (PiC), encoded by SLC25A3, in bioenergetics is well accepted. However, little is known about the mechanisms mediating the cellular impairments induced by pathological SLC25A3 variants.
Acoba, Michelle G., Anderson-Pullinger, Lauren, Claypool, Steven M., Golenár, Tünde, Gál, Aniko, Hajnóczky, György, Li, Qipei, Moffat, Cynthia, Seifert, Erin L., Sondheimer, Neal   +9 more
core   +2 more sources

Association between serum bicarbonate and low mid‐upper arm circumference in patients with non‐dialysis‐dependent chronic kidney disease: A cross‐sectional study

Nutrition in Clinical Practice, EarlyView.
Abstract Background Although previous experimental studies showed that metabolic acidosis promoted muscle catabolism and impaired protein synthesis, few epidemiological studies reported an independent association between serum bicarbonate levels and muscle atrophy in patients with chronic kidney disease (CKD).
Nobuhisa Morimoto, Shintaro Mandai, Tamami Fujiki, Fumiaki Ando, Takayasu Mori, Koichiro Susa, Shotaro Naito, Eisei Sohara, Tatsuhiko Anzai, Kunihiko Takahashi, Wataru Akita, Akihito Ohta, Shinichi Uchida, Soichiro Iimori   +13 more
wiley   +1 more source

Glucose availability and sensitivity to anoxia of isolated rat peripheral nerve [PDF]

, 1991
The contrast between resistance to ischemia and ischemic lesions in peripheral nerves of diabetic patients was explored by in vitro experiments. Isolated and desheathed rat peroneal nerves were incubated in the following solutions with different glucose ...
DYCK P. J., GRAFE P., K., GREENE D. A, KRAIG R. P., M. Strupp, P. Grafe, R. Jund, SIESJO B. K, STRUPP M., R., THOMAS P. K., U. Schneider, W.   +11 more
core   +1 more source

Exploratory Laparotomy After Routine Cardiac Surgery: Results From 17,000 Patients

World Journal of Surgery, EarlyView.
Exploratory laparotomy is rare after open‐heart surgery, and it was performed for gastrointestinal complications that occurred in the context of other severe postoperative complications. Several factors were associated with the need for exlap, including increasing age, pre‐existing renal and vascular disease, and pre‐ and post‐operative shock. ABSTRACT
Megan Turner, James A. Brown, Pyongsoo Yoon, Michelle Yoon, Zeyu Liu, Zihan Feng, Ryan Rivosecchi, Holt Murray, Jianhui Zhu, Floyd Thoma, Derek Serna‐Gallegos, David Kaczorowski, Johannes Bonatti, Danny Chu, Irsa Hasan, Takuya Ogami, Ibrahim Sultan   +16 more
wiley   +1 more source

Is the COBRA‐OS 4 French Aortic Occlusion Device Feasible for Partial REBOA?

World Journal of Surgery, EarlyView.
Noncompressible torso hemorrhage is a leading cause of preventable death. Resuscitative endovascular balloon occlusion of the aorta (REBOA) is used to control hemorrhage but full aortic occlusion is limited by distal ischemia. Partial REBOA (pREBOA) allows some distal perfusion to prolong occlusion, but precise balloon titration is difficult with ...
Adam Power, Asha Parekh, Samuel Jessula, Joao Rezende‐Neto, Laura J. Moore   +4 more
wiley   +1 more source

Vitamin B1 for type B metabolic acidosis: An underrecognized approach

Saudi Journal of Kidney Diseases and Transplantation, 2018
Lactic acidosis is a life-threatening and rather common complication and reason for consultation to the nephrologist. The cause for this condition is usually thought to be secondary to hypoperfusion and ischemia collectively.
Adriana Dejman, Jason Riveros
doaj   +1 more source

Incidence of lactic acidosis toxicity among patients on stavudine or zidovudine containing antiretroviral therapy at Lighthouse clinics [PDF]

, 2012
Although stavudine and zidovudine remain frequently used in low-income countries in Africa, they are associated with long-term toxicities. Lactic acidosis is one of the most serious toxicities in antiretroviral treatment (ART) and occurs predominantly in
C Speight, H Tweya, L Kachere, S Phiri, W Ng'   +4 more
core   +1 more source

Peri‐operative management of diabetes mellitus: a multidisciplinary consensus statement from the Association of Anaesthetists and the Joint British Diabetes Societies for Inpatient Care group

Anaesthesia, EarlyView.
Summary Introduction Surgery in patients with diabetes mellitus is associated with increased morbidity and mortality compared with those who do not have diabetes mellitus. This is likely multifactorial and could be attributed to organisational issues; dysglycaemia; hospital‐acquired diabetic ketoacidosis; errors with insulin prescribing and ...
Nicholas A. Levy, Kariem El‐Boghdadly, Dileep N. Lobo, Daniel J. Stubbs, Parizad Avari, Donal Buggy, Claire Frank, Kim Howson, Jinty Moffett, Emma Morris, Omar G. Mustafa, Glynn Nash, Pádraig Ó Scanaill, Sarah Procter, Gerry Rayman, Kim Russon, Caroline Thomas, Sarah Tinsley, Allan Xu, Ketan Dhatariya   +19 more
wiley   +1 more source

IONIZED CALCIUM IN ACIDOSIS: DIFFERENTIAL EFFECT OF HYPERCAPNIC AND LACTIC ACIDOSIS [PDF]

, 2017
The effects of various forms of acidosis on ionized calcium concentrations were investigated in vivo in rabbits and in vitro in human plasma. Calculation of least square regression equations of ionized calcium (mM) on pH yielded the following regression ...
BACHMANN, U., SCHAER, H.
core  

Secular Trend in Glycaemic Management in Type 2 Diabetes Patients With and Without Cirrhosis Between 2000 and 2023: A Territory‐Wide Cohort Study

Alimentary Pharmacology &Therapeutics, EarlyView.
In this territory‐wide cohort study, improving glycemic control can be observed regardless of cirrhosis status. Oral antidiabetic medication was more often used in the non‐cirrhosis group, and insulin was preferred in patients with decompensated cirrhosis, who exhibited an increasing incidence of hypoglycemia over the years and need individualized ...
Mary Yue Wang, Sherlot Juan Song, Nana Peng, Grace Lai‐Hung Wong, Vincent Wai‐Sun Wong, Jimmy Che‐To Lai, Terry Cheuk‐Fung Yip   +6 more
wiley   +1 more source