Results 101 to 110 of about 36,482 (221)

Lactic acidosis in diabetics.

South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1975
Eleven diabetic patients were admitted to Groote Schuur Hospital during the past year with severe lactic acidosis; 8 patients recovered and 3 died. All were middle-aged or elderly, taking phenformin, and suffering from a complicating disorder including Gram-negative septicaemia, shock, chronic hepatic disease and chronic renal disease.
Vinik, AI, Jackson, WPU
openaire   +2 more sources

Comparative Investigation of the Effects of Season (Summer–Winter) and Sex on Tear Production and Intraocular Pressure in Saanen and Honamlı Goats

Veterinary Ophthalmology, Volume 29, Issue 4, July 2026.
ABSTRACT Objective To evaluate the effects of season (summer vs. winter) and sex on tear production (Schirmer tear test; STT‐I) and intraocular pressure (IOP) in Honamlı and Saanen goats raised under similar environmental conditions. Materials and Methods A total of 120 clinically healthy goats (Honamlı and Saanen; 30 females and 30 males per breed ...
Eser Çakmakçi, Ahmet Gürsel, Ali Belge   +2 more
wiley   +1 more source

Antimicrobial prescribing guidelines for feedlot cattle

Australian Veterinary Journal, EarlyView.
P Cusack, T Batterham, SW Page, GF Browning, JM Norris   +4 more
wiley   +1 more source

Patterns of Postictal Abnormalities in Relation to Status Epilepticus in Adults

Annals of Clinical and Translational Neurology, Volume 13, Issue 6, Page 1118-1128, June 2026.
ABSTRACT Objective Abnormalities on peri‐ictal diffusion‐weighted magnetic resonance imaging (DWI‐PMAs) are well‐established for patients with status epilepticus (SE), but knowledge on patterns of DWI‐PMAs and their prognostic impact is sparse. Methods This systematic review and individual participant data meta‐analysis included observational studies ...
Andrea Enerstad Bolle, Silvana Sarria‐Estrada, Thomas Bonduelle, Bertram Daniel Dynesen, Manuel Toledo, Zhu Chung Che, Kjell Heuser, Anastasios Chatzikonstantinou, Jérôme Aupy, Udaya Seneviratne, Estevo Santamarina Perez, Christoph Patrick Beier   +11 more
wiley   +1 more source

Lactic Acidosis Secondary to Metformin in a Patient Presenting with Acute Renal Failure due to Diarrhea: Case Report

Turkish Journal of Nephrology, 2019
Metformin is a biguanide used in the treatment of type 2 diabetic patients with normal renal function. Lactic acidosis is the most serious side effect of metformin. Renal failure is the most common cause of reduced lactate excretion.
Mustafa YAPRAK, Mehmet Nuri TURAN, Aygül ÇELTİK, Meltem SEZİŞ DEMİRCİ, Erhan TATAR, Arzu Nazlı ZEKA, Hüsnü PULLUKÇU, Mehmet ÖZKAHYA   +7 more
doaj  

Thiamine deficiency-related myocardial dysfunction: A hidden cause of refractory lactic acidosis and shock in severe diabetic ketoacidosis: A case report

Journal of Pediatric Critical Care
Diabetic ketoacidosis (DKA) is a life-threatening complication of diabetes mellitus, characterized by hyperglycemia, ketosis, and metabolic acidosis. Severe dehydration and hypovolemic shock in severe DKA are common, but myocardial dysfunction and lactic
Sannarudrappa Sagar, Namita Ravikumar, B. M. Sunil Kumar, V. Subrahmanya Murti   +3 more
doaj   +1 more source

T‐Cell Exhaustion in the Tumor Microenvironment: Subcellular Dysfunction, Pan‐Cancer Characteristics, and Therapeutic Interventions

Advanced Science, Volume 13, Issue 33, 15 June 2026.
This study elucidates the mechanisms of subcellular multidimensional collapse in exhausted T cells. By specifically targeting the nucleus, mitochondria, and endoplasmic reticulum, strategic interventions can effectively remodel the compromised organelle network. This integrated approach drives comprehensive T cell resuscitation, ultimately establishing
Mingxing Wang, Wanhui Dong, Jian Chen, Zhangjie Zhou, Shujuan Fu, Tingting Wu, Haiyan Jiang, Zhiying Wang, Zhixian Zhong, Yi Zhong   +9 more
wiley   +1 more source

Rapid Genome and Exome Sequencing in Inpatients: Clinical Impact at a Tertiary Academic Medical Center

American Journal of Medical Genetics Part A, Volume 200, Issue 6, Page 1337-1346, June 2026.
ABSTRACT The objective of this study is to describe outcomes of rapid exome (rES) and rapid genome sequencing (rGS) in an inpatient setting. This is a retrospective cohort of inpatients with rES or rGS during their hospitalization between April 2016 and November 2023.
Cecilia M. Kessler, Bryce A. Schuler, Elizabeth A. Jasper, Janet Talbert, Laura Duncan, Mackenzie Mosera   +5 more
wiley   +1 more source

Cytosolic Phosphoenoylpyruvate Carboxykinase Deficiency: Clinical, Biochemical, and Genetic Features of Five Non‐Finnish Patients

American Journal of Medical Genetics Part A, Volume 200, Issue 6, Page 1192-1203, June 2026.
ABSTRACT Cytosolic phosphoenoylpyruvate carboxykinase (PEPCK‐C) is an essential, rate‐limiting enzyme in the gluconeogenesis pathway. PEPCK‐C deficiency presents with hypoglycaemia, hyperlactataemia and hepatopathy, and was first reported in association with bi‐allelic PCK1 variants in 2014.
Isaac Bernhardt, Polona Le Quesne Stabej, Claire Hart, Mark De Hora, Sarah Hulley, Mark Anderson, Harry G. Leitch, Hugh Lemonde, Bryony Ryder, James Davison   +9 more
wiley   +1 more source

Neuroprotective Effects of Phenothiazines on Acute Ischemic Stroke

CNS Neuroscience &Therapeutics, Volume 32, Issue 6, June 2026.
For acute ischemic stroke due to large vessel occlusion, adjunctive neuroprotective therapy with mechanical thrombectomy is important; however, current treatment options are relatively limited. Phenothiazines such as chlorpromazine and promethazine (C + P) have shown potential neuroprotective effects in preclinical studies.
Qi Wang, Weili Li, Di Wu, Shuaili Xu, Xunming Ji   +4 more
wiley   +1 more source