Results 131 to 140 of about 65,295 (252)

Lactic Acidosis Secondary to Metformin in a Patient Presenting with Acute Renal Failure due to Diarrhea: Case Report

Turkish Journal of Nephrology, 2019
Metformin is a biguanide used in the treatment of type 2 diabetic patients with normal renal function. Lactic acidosis is the most serious side effect of metformin. Renal failure is the most common cause of reduced lactate excretion.
Mustafa YAPRAK, Mehmet Nuri TURAN, Aygül ÇELTİK, Meltem SEZİŞ DEMİRCİ, Erhan TATAR, Arzu Nazlı ZEKA, Hüsnü PULLUKÇU, Mehmet ÖZKAHYA   +7 more
doaj  

Determining predictors of underlying etiology and clinical deterioration in patients with physiologic instability in the emergency department [PDF]

, 2013
Thesis (M.A.)--Boston UniversityShock is a critical state defined by inadequate oxygen delivery to tissues. It is well known in the critical care community that early diagnosis and treatment of shock are crucial to improving patient outcomes. However, in
Day, Danielle E.
core   +1 more source

Effectiveness of Riboflavin in Inherited Metabolic Diseases: A Systematic Review

Journal of Inherited Metabolic Disease, Volume 49, Issue 3, May 2026.
ABSTRACT Riboflavin (RF, vitamin B2) is an essential vitamin of which the co‐factors are critical to numerous cellular processes. RF is used as a treatment for inherited metabolic diseases (IMDs), although its effectiveness in many disorders has not been established.
Bregje Jaeger, Nina N. Stolwijk, Femke Aaldering, Charlotte A. Ruys, Marije Smits, Nicole I. Wolf, Carla E. M. Hollak, Annet M. Bosch   +7 more
wiley   +1 more source

Lactic acidosis. [PDF]

BMJ, 1971
K G, Alberti, J, Corbett, T D, Hockaday, D H, Williamson   +3 more
openaire   +4 more sources

Thiamine deficiency-related myocardial dysfunction: A hidden cause of refractory lactic acidosis and shock in severe diabetic ketoacidosis: A case report

Journal of Pediatric Critical Care
Diabetic ketoacidosis (DKA) is a life-threatening complication of diabetes mellitus, characterized by hyperglycemia, ketosis, and metabolic acidosis. Severe dehydration and hypovolemic shock in severe DKA are common, but myocardial dysfunction and lactic
Sannarudrappa Sagar, Namita Ravikumar, B. M. Sunil Kumar, V. Subrahmanya Murti   +3 more
doaj   +1 more source

Toxic alcohols [PDF]

, 2018
Kraut, Jeffrey A, Mullins, Michael E
core   +2 more sources

Shifting Towards Empagliflozin First‐Line Therapy in Glycogen Storage Disease Type Ib: A Nationwide Real‐World Study

Journal of Inherited Metabolic Disease, Volume 49, Issue 3, May 2026.
ABSTRACT Neutrophil dysfunction and neutropenia are burdensome findings in glycogen storage disease type Ib (GSDIb). Treatment with granulocyte‐colony stimulating factor (G‐CSF) often corrects neutropenia but fails to improve clinical symptoms like inflammatory bowel disease (IBD).
Sema Kalkan Uçar, Neslihan Önenli Mungan, Gülden Fatma Gökçay, Ayşe Çiğdem Aktuğlu Zeybek, Sebile Kılavuz, Seda Güneş, Fatih Kardaş, Pelin Teke Kısa, Kısmet Çıkı, Aynur Küçükçongar Yavaş, Ayça Burcu Kahraman, Merve Yoldaş Çelik, Ebru Canda, Deniz Kor, Meryem Karaca, Tanyel Zübarioğlu, Emine Genç, Havva Yazıcı, Fatma Derya Bulut, Şebnem Kılıç, Hanım Aghakıshılı, Fehime Erdem Karapınar, Ezgi Burgaç, Ertuğrul Kıykım, Alperen Elek, Nihal Kardaş, Ekrem Ünal, Tuba Hilkay Karapınar, Meryem Albayrak, Canan Albayrak, Ayşegül Ünüvar, Saskia B. Wortmann, Deniz Yılmaz Karapınar   +32 more
wiley   +1 more source

Antenatal Presentation of MRPS22‐Related Mitochondrial Disease Confirmed With Rapid Proteomics

JIMD Reports, Volume 67, Issue 3, May 2026.
ABSTRACT MRPS22‐related mitochondrial disease (MIM#611719) is a rare autosomal recessive disorder caused by defects in the mitochondrial ribosomal protein S22, a component of the small mitoribosomal subunit essential for mitochondrial translation. Of the few reported cases, most present antenatally with a severe phenotype, conveying a poor prognosis ...
Liana N. Semcesen, Megan Ball, Daniella H. Hock, Juliet Kaye, Aimee Woods, Lucas De Jong, MitoMDT Diagnostic Network for Genomics and Omics, David R. Thorburn, Aleksandra Filipovska, Michael T. Ryan, David A. Stroud, Diana Stojanovski, David Coman, Sean Murray, Ryan L. Davis, John Christodoulou, Suzanne C. E. H. Sallevelt, Roula Ghaoui, Cas Simons, Stefan J. Siira, Shanti Balasubramaniam, Alison G. Compton, Daniel G. MacArthur, Nicole J. Lake, Drago Bratkovic, Joy Lee, Maina Kava, Amanda Samarasinghe, Yoni Elbaum, Catherine Atthow, Pauline McGrath, Tegan Stait, Rocio Rius, Liana N. Semcesen, Megan Ball, Daniella Hock, Luke E. Formosa, Ellenore M. Martin, Madeleine Harris, John Christodoulou, David R. Thorburn, Alison G. Compton, David A. Stroud, Jan Liebelt   +43 more
wiley   +1 more source

MELAS‐Like Mitochondrial Encephalopathy With Catatonia Associated With a Pathogenic MT‐ND3 (m.10158 T > C) Mutation: A Case Report and Literature Review

Progress in Neurology and Psychiatry, Volume 30, Issue 2, May 2026.
Abstract Mitochondrial Encephalomyopathy, Lactic Acidosis, and Stroke‐like episodes (MELAS) is a rare multisystem mitochondrial disorder primarily caused by mutations in mitochondrial DNA. While it typically presents with stroke‐like episodes, seizures, and lactic acidosis, recent evidence highlights a broader clinical spectrum, including ...
Faezeh Khorshidian, Vajiheh Aghamollaii, Mohammadreza Mousavipour, Setareh Rassa   +3 more
wiley   +1 more source

The Acidic Conductor: How Tumor Acidosis Orchestrates Metabolic Adaptation

MedComm – Oncology, Volume 5, Issue 2, June 2026.
Chen Xu, Tao Yang, Xinghua Long
wiley   +1 more source