Results 131 to 140 of about 36,716 (234)

Thrombocytosis and the generation of platelet‐derived microparticles in the pathophysiology of sickle cell disease

British Journal of Haematology, Volume 209, Issue 2, Page 420-431, August 2026.
Thrombocytosis is associated with an increased production of platelet‐derived microparticles from activated platelets, which contribute to vaso‐occlusion in sickle cell disease by perpetuating the cycle of inflammation, procoagulant state and endothelial dysfunction.
Giao N. Lê, Anna Dillon, Owen P. Smith, Corrina McMahon   +3 more
wiley   +1 more source

Metformin Toxicity Unmasked by Obstructive Uropathy: A Case of Metformin Associated Lactic Acidosis and Euglycemic Diabetic Ketoacidosis. [PDF]

Discoveries (Craiova)
Khan RS, Patla A, Ayyazuddin M, Michaeil G, Shah R, Rajaram S.   +5 more
europepmc   +1 more source

High‐intensity interval training has a greater effect on metabolic profiles than the dietary composition in male rats

Physiological Reports, Volume 14, Issue 15, August 2026.
High‐intensity interval training (HIIT) induces skeletal muscle metabolic adaptations by modulating amino acid‐related pathways largely independent of dietary fat intake, while under a normal diet it also alters specific glycolytic metabolites, including lactic acid.
Asiyeh Taji Tabas, Marziyeh Saghebjoo, Reza Ghahremani, Mehdi Hedayati   +3 more
wiley   +1 more source

Pseudo-Ischemic ECG Changes in a Patient With Profound Mixed Metabolic Acidosis Due to Metformin Use. [PDF]

JACC Case Rep
Grant JJ, Wilson DP, Schindler JT.
europepmc   +1 more source

Amino acid homeostasis in the kidney: Physiological roles and pathological dysregulation

Physiological Reports, Volume 14, Issue 15, August 2026.
Abstract Amino acids are fundamental to life as protein building blocks and key regulators of metabolism and signaling. The kidney plays a critical, yet underappreciated, role in amino acid homeostasis through three interconnected pillars: selective glomerular filtration, efficient tubular reabsorption, and metabolic processing, which includes de novo ...
Shuo Liu, Caifeng Shi, Yang Zhou, Chunsun Dai   +3 more
wiley   +1 more source

Severe Metformin-Associated Lactic Acidosis-A Case Report. [PDF]

Clin Case Rep
Artinyan E, Nikolov G, Valcheva E, Baniya P, Sritharan D, Khan A, Vaysilova M, Dimov N.   +7 more
europepmc   +1 more source

Concurrent Metformin-Associated Lactic Acidosis and Euglycemic Diabetic Ketoacidosis Without Sodium-Glucose Cotransporter 2 Inhibitor Exposure: A Case Report and Literature Review. [PDF]

Cureus
Almahmood M, Abuafifeh L, Saied ASS, Fadul A, Al Qaryoute A, Ahmed H, Tariq MA.   +6 more
europepmc   +1 more source

Where Is the Lactate Coming From? An Unusual Presentation of Persistent Lactic Acidosis. [PDF]

Cureus
Sadiq W, Waleed MS.
europepmc   +1 more source

Metformin Use and Clinical Outcomes in Very Elderly Patients with Type 2 Diabetes and Chronic Kidney Disease. [PDF]

Medicina (Kaunas)
Marchini M.
europepmc   +1 more source

The anion gap: basic chemistry, powerful clinical implications. [PDF]

Singapore Med J
Fong JMN, Tang GXJ, See KC.
europepmc   +1 more source