Results 141 to 150 of about 65,295 (252)

The Dairy Ruminant Gut Microbiome: Profile, Responsiveness to Seasonality and Impact on Milk Quality

open access: yesEnvironmental Microbiology, Volume 28, Issue 5, May 2026.
The dairy ruminant gut microbiome that is shaped by host and diet is affected by seasonality and rearing. These factors can impact dairy productivity and milk quality potentially through the gut microbiota. ABSTRACT The gut microbiome (GM) and particularly the rumen microbiome (RM) affect the ruminant health and they are associated with milk quality ...
Alexandra Ntemiri   +2 more
wiley   +1 more source

Clearance of mannitol for assessment of glomerular filtration rate in chronic kidney disease: A validation against iohexol clearance

open access: yesClinical Physiology and Functional Imaging, Volume 46, Issue 3, May 2026.
Abstract This study evaluates mannitol as a clearance marker for measuring glomerular filtration rate (GFR) in outpatients with chronic kidney disease (CKD). Multi‐sample iohexol clearance served as the reference method. Twenty patients with CKD, stages 3–4, received bolus injections of both clearance markers simultaneously.
Katalin Kiss   +3 more
wiley   +1 more source

Effectiveness and Safety of Evogliptin in Patients With Type 2 Diabetes Mellitus: A Multicenter, Prospective, Observational Study

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 5, Page 4112-4120, May 2026.
ABSTRACT Aims Evogliptin, a dipeptidyl peptidase‐4 inhibitor with a glucose‐dependent mechanism of action, is widely used as a monotherapy or in combination with other agents. However, observational studies in routine clinical settings remain limited.
Jun Hwa Hong   +14 more
wiley   +1 more source

Beyond the chaos: How architecture structures tumour biology

open access: yesThe FEBS Journal, Volume 293, Issue 9, Page 2519-2540, May 2026.
Tissue architecture shapes tumour initiation and progression through multiple interconnected layers continuously remodelled over time. This review outlines how physical forces, biochemical cues, cellular niches and systemic influences contribute to tumour evolution.
Lea Dörner   +3 more
wiley   +1 more source

Impact of renal function on antidiabetic drug selection in Japan: A real‐world analysis using the J‐DREAMS database

open access: yesJournal of Diabetes Investigation, Volume 17, Issue 5, Page 801-809, May 2026.
Using a large Japanese real‐world database, we examined antidiabetic drug selection in first and second therapy stratified by renal function and study period. The earlier initiation of SGLT2 inhibitors and GLP‐1 receptor agonists increased over time, particularly in second therapy, with prescribing patterns increasingly aligned across renal function ...
Masashi Kubota   +2 more
wiley   +1 more source

Lactic acidosis [PDF]

open access: yesThe American Journal of Medicine, 1970
openaire   +3 more sources

Safety of acute exposure to the food additive glycerol (E 422) from beverages

open access: yesEFSA Journal, Volume 24, Issue 5, May 2026.
Abstract The European Commission requested EFSA to assess the acute exposure to glycerol (E 422) from slush ice drinks and de‐alcoholised wine. The acute exposure assessment was conducted on a single‑consumption‑event basis considering the reported use levels and analytical data of glycerol in slush ice drinks and the proposed maximum level of 50,000 ...
EFSA Panel on Food Additives and Flavourings (FAF)   +22 more
wiley   +1 more source

One‐Step and Universal Strategy for the Synthesis of Hypermodified Uracil Phosphoramidites acp3U and cmnm5U

open access: yesChemistry – A European Journal, Volume 32, Issue 16, 25 April 2026.
One‐step, highly efficient, and scalable synthesis of acp3U phosphoramidite is described, as well as a new alternative synthesis of cmnm5U phosphoramidite from a highly versatile intermediate. Latter could be scaled‐up, split, and aliquots turned simultaneously into cmnm5U, nm5U, and mnm5U.
Ewa Mejdr   +3 more
wiley   +1 more source

Gaining from Improved Dairy Cow Nutrition: Economic, environmental and animal health benefits [PDF]

open access: yes
A majority of UK dairy herds have the potential to increase profitability by improving the ration of their cows. This paper reports that gains averaging around £100 per cow have been made within one year of adopting the Keenan Hi-Fibre ration by 239 UK ...
Beever, David E., Colman, David R.
core   +1 more source

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