Results 201 to 210 of about 134,882 (291)

Acidosis

open access: hybrid, 1928
Q. B. Lee
openalex   +1 more source

Development of a Protocol for Long‐Term Ex Vivo Normothermic Machine Perfusion of Rodent Livers

open access: yesArtificial Organs, EarlyView.
Long‐term normothermic machine perfusion (LT‐NMP) is the next revolution in liver transplantation and could support grafts for days, and potentially weeks. A rodent model of LT‐NMP is important for laboratory research, but has not been achieved until now. Our study describes a protocol for LT‐NMP of rodent livers.
Mark Ly   +9 more
wiley   +1 more source

Real‐World Therapeutic Hypothermia for Neonatal HIE: Neurodevelopmental Outcomes and Predictors

open access: yesActa Paediatrica, EarlyView.
ABSTRACT Aim This study assessed neurodevelopmental outcomes in neonates with hypoxic‐ischemic encephalopathy (HIE) treated with therapeutic hypothermia (TH) outside randomised controlled trials (RCTs). It also aimed to identify predictors of outcomes and evaluate TH practices across centres.
Luca Bedetti   +23 more
wiley   +1 more source

Human hypoxia models in aerospace medicine: Potential applications for human pharmacological research

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aerospace medicine required controlled terrestrial models to investigate influences of altered atmosphere conditions, such as hypoxia, on human health and performance. These models could potentially be expanded to encompass disease conditions or treatment targets regulated through hypoxia or hypercapnia.
Titiaan E. Post   +4 more
wiley   +1 more source

Diagnostic Yield and Clinical Impact of a Small Genetic Panel for Kidney Disease: A Multicenter, Retrospective European Study

open access: yesClinical Genetics, EarlyView.
In a multicenter study of 692 patients with kidney disease, a 44‐gene panel achieved a 36% diagnostic yield. The 36% yield was not significantly lower than with larger panels or whole‐exome sequencing. A post hoc machine‐learning model identified key predictors to stratify patients into four risk bins (11%–74% yield), enabling more cost‐effective ...
Silvia Giovanella   +22 more
wiley   +1 more source

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