British Journal of Pharmacology, EarlyView.Blood vascular permeability is a hallmark of cancer and acts as an active driver of metastatic dissemination. Metastasis accounts for the vast majority of cancer deaths, yet most work has focussed on tumour‐intrinsic traits and angiogenesis, while the specific contribution of endothelial barrier regulation to intravasation and extravasation remains ...
Pierre Boucher +6 more
wiley +1 more source
The Acid-Base Effects of Albumin in Sepsis: Reconciling the Stewart Physicochemical Approach with the Traditional Buffer-Base Paradigm. [PDF]
J Clin MedOrso D, Saro R, Della Rocca G.
europepmc +1 more source
CD93—An emerging vascular target in cancer therapy
British Journal of Pharmacology, EarlyView.Abstract CD93 is a single‐pass transmembrane glycoprotein that belongs to the C‐type lectin domain group XIV family of proteins. Although it is known to be expressed in other cell types, namely, in some subsets of immune cells, CD93 is primarily expressed on endothelial cells, where it acts as a crucial regulator of angiogenesis.
Beatriz de Alves Pereira +3 more
wiley +1 more source
Type B Lactic Acidosis and Acute Kidney Injury Heralding B-Lymphoblastic Leukemia/Lymphoma. [PDF]
Mediterr J Hematol Infect DisSu Z, Fan Q, Jiang Y.
europepmc +1 more source
British Journal of Pharmacology, EarlyView.Disruption of intracellular ionic homeostasis is a convergent pathological feature across diverse neurological injuries and disorders, including ischaemic and haemorrhagic stroke, hypoxic–ischaemic brain injury, traumatic brain injury, epilepsy and brain tumour.
Xinyang Zhang +5 more
wiley +1 more source
Nonlinear regression modeling of ruminal fermentation dynamics in buffered diets using in vitro gas production. [PDF]
PLoS OneAsadollahi Seyedabadi Z +3 more
europepmc +1 more source
Clinical &Experimental Ophthalmology, EarlyView.ABSTRACT Background This trial aimed to evaluate the efficacy of oral acetazolamide in reducing cystoid fluid collections (CFC) and improving visual function in patients with X‐linked retinoschisis (XLRS). Methods In this investigator‐initiated, single centre, open‐label, randomised controlled trial, XLRS patients aged ≥ 12 years with fovea‐involving ...
Jonathan Hensman +15 more
wiley +1 more source
Monocarboxylate transporter 1 deficiency: a rare case report and systematic review of genetically confirmed cases. [PDF]
Ann Med Surg (Lond)Khalifa YM +4 more
europepmc +1 more source
A New Case of Lethal Congenital Contracture Syndrome Type 3 With Hyperinsulinism and Optic Atrophy
Clinical Genetics, EarlyView.PIP5K1C‐related lethal congenital contracture syndrome with hyperinsulinism and optic atrophy. ABSTRACT Lethal congenital contracture syndrome 3 (LCCS3, MIM #611369) is a rare autosomal recessive neuromuscular disorder caused by biallelic loss‐of‐function (LOF) variants in PIP5K1C, reported in only two families to date.
Tameemi Abdalla Moady +3 more
wiley +1 more source
Complete Recovery Following Intentional Potassium Cyanide Poisoning Despite Delayed Hydroxocobalamin Administration: A Case Report. [PDF]
CureusLichtarska K +8 more
europepmc +1 more source