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Biochemistry of exercise-induced metabolic acidosis [PDF]
American Journal of Physiology - Regulatory Integrative and Comparative Physiology, 2004 The development of acidosis during intense exercise has traditionally been explained by the increased production of lactic acid, causing the release of a proton and the formation of the acid salt sodium lactate.
Robert Robergs
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AACN Clinical Issues: Advanced Practice in Acute and Critical Care, 1997
Metabolic acidosis is a pathophysiologic state that is associated with serious morbidities and mortality. The diagnosis of metabolic acidosis is perplexing for novice and expert advanced practice nurses for many reasons. Its differential diagnosis is broad and includes common and rare, complex disease.
N, Szaflarski, C W, Hanson
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Metabolic acidosis is a pathophysiologic state that is associated with serious morbidities and mortality. The diagnosis of metabolic acidosis is perplexing for novice and expert advanced practice nurses for many reasons. Its differential diagnosis is broad and includes common and rare, complex disease.
N, Szaflarski, C W, Hanson
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Southern Medical Journal, 1990
Rapid, extreme expansion of the extracellular fluid with solutions devoid of acid or alkali theoretically can produce a metabolic acidosis, due to buffer dilution. This phenomenon has previously been demonstrated only in experimental animal studies. We have reported what we believe to be the first documented case of hypobicarbonatemia and metabolic ...
D A, Goodkin, R M, Raja, A, Saven
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Rapid, extreme expansion of the extracellular fluid with solutions devoid of acid or alkali theoretically can produce a metabolic acidosis, due to buffer dilution. This phenomenon has previously been demonstrated only in experimental animal studies. We have reported what we believe to be the first documented case of hypobicarbonatemia and metabolic ...
D A, Goodkin, R M, Raja, A, Saven
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Endocrinology and Metabolism Clinics of North America, 1993
Lactic acidosis is the most common metabolic acidosis. At clinical presentation, several causes usually can be identified. The liver is a major site of removal of lactate and hydrogen ions, and abnormalities in the aerobic metabolism of lactate by mitochondria in hepatocytes and other cells may contribute to many clinical conditions in which ...
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Lactic acidosis is the most common metabolic acidosis. At clinical presentation, several causes usually can be identified. The liver is a major site of removal of lactate and hydrogen ions, and abnormalities in the aerobic metabolism of lactate by mitochondria in hepatocytes and other cells may contribute to many clinical conditions in which ...
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Respiratory Care, 2001
Metabolic acidosis occurs in a number of diseases and even certain normal activities such as heavy exercise. It arises from increased endogenous acid production, exogenous acid (or acid-precursor) administration, base losses, and depression of renal acid secretion.
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Metabolic acidosis occurs in a number of diseases and even certain normal activities such as heavy exercise. It arises from increased endogenous acid production, exogenous acid (or acid-precursor) administration, base losses, and depression of renal acid secretion.
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Emergency Medicine Clinics of North America, 1989
This article reviews acid-base homeostasis and discusses the approach to the acidotic patient, with special reference to problems commonly encountered in emergency practice. General principles of therapy are presented, and their application to specific types of life-threatening metabolic acidosis addressed.
T, Kearns, A B, Wolfson
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This article reviews acid-base homeostasis and discusses the approach to the acidotic patient, with special reference to problems commonly encountered in emergency practice. General principles of therapy are presented, and their application to specific types of life-threatening metabolic acidosis addressed.
T, Kearns, A B, Wolfson
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Disease-a-Month, 1989
An understanding of the pathophysiology of lactic acidosis is crucial in facilitating the optimal care of critically ill patients. The relevant biochemistry of lactic acidosis is reviewed, and the more controversial aspects relating to the genesis of the acidosis are highlighted.
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An understanding of the pathophysiology of lactic acidosis is crucial in facilitating the optimal care of critically ill patients. The relevant biochemistry of lactic acidosis is reviewed, and the more controversial aspects relating to the genesis of the acidosis are highlighted.
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