Results 231 to 240 of about 167,619 (297)

Periodontitis‐Associated Circulating EVs Promote Colorectal Cancer Progression via Carnosine‐Mediated Acidosis Adaptation

Cell Proliferation, EarlyView.
This study identifies a link between periodontitis and CRC progression mediated by carnosine‐enriched circulating EVs. These EVs target the intestine and elevate tumour cell intracellular pH (pHi), which rescues lysosomal function. This process drives a transition from dysfunctional lysosomes to functional ones, promoting a high malignancy phenotype in
Ruoyi Wu, Zihan Cai, Hualing Sun, Haikun Yu, Bicheng Zhang, Chi Zhang, Yi Fan, Xiaoxuan Zhu, Yueqi Ni, Yu Cui, Kaixin Wang, Zhe Li, Xinyi Zhou, Qing He, Yanru Wu, Yufeng Zhang   +15 more
wiley   +1 more source

Peritoneal Dialysis in Infant Methylmalonic Acidemia: Effective Management Despite Sterile Peritonitis. [PDF]

Cureus
Manir MZ, Haldar U, Gopal N, Mohanraj PS, Girish M, Dhawan D.   +5 more
europepmc   +1 more source

The cerebral palsy directed acyclic graph: A structural causal model of aetiology

Developmental Medicine &Child Neurology, EarlyView.
The first international cerebral palsy directed acyclic graph (CP‐DAG) maps over 100 nodes and 370 links across biological, clinical, and social domains, offering a unified causal framework to guide research and identify knowledge gaps. Abstract Aim To describe the development of the initial version of the cerebral palsy (CP) directed acyclic graph ...
Shona Goldsmith, Sarah McIntyre, Nadia Badawi, Bernard Dan, Steven Day, Kate Himmelmann, Sandra Julsen Hollung, Bo Jacobsson, Gija Rackauskaite, Robert J. Reynolds   +9 more
wiley   +1 more source

Marked Increase in Diabetic Ketoacidosis Rates With Modest Increase in HbA1c Elevation at Diabetes Diagnosis in Swedish Children

Acta Paediatrica, EarlyView.
Frida Sundberg, Katarina Eeg‐Olofsson, Karin Åkesson   +2 more
wiley   +1 more source

Under‐ and overdosing insulin in the hospital: A retrospective cohort study of dose deviation and patient outcomes

Diabetic Medicine, EarlyView.
Abstract Aims Glycaemic abnormalities during hospitalization are common and linked to morbidity and mortality, yet little is known about how deviations from guideline‐recommended insulin dosing affect outcomes. The aim of this study is to examine whether deviation from an expected insulin dose in non‐critically ill hospitalized adults with type 2 ...
Hussein Zaitoon, Sher Matsri, Shira Nagler, Matteo M. Lalovich, Ralph A. DeFronzo, Eugene Feigin   +5 more
wiley   +1 more source

Non-occlusive mesenteric ischemia complicated by ischemic hepatitis presenting as severe lactic acidosis: a case report. [PDF]

Front Med (Lausanne)
Geng H, Ye H, Lei M.
europepmc   +1 more source

Pendrin inhibitor PDSinh-C01 reverses salt-sensitive hypertension and metabolic acidosis in the 5/6 nephrectomy rat model. [PDF]

Pflugers Arch
Rudolphi CF, Goos Y, Musterd-Bhaggoe U, van Veghel R, Garrelds IM, Danser AHJ, Karmakar J, Cil O, Imenez Silva PH, Hoorn EJ.   +9 more
europepmc   +1 more source

Normoglycemic High Anion Gap Metabolic Acidosis With Hyperkalemia: An Unusual Presentation of Alcoholic Ketoacidosis. [PDF]

Cureus
Mishra A, Shagil M, Singh L.
europepmc   +1 more source

Tislelizumab-induced distal renal tubular acidosis presenting with life-threatening hypokalemia: a case report. [PDF]

Front Immunol
Xu J, Qin L, Wang P, Liu Z, Yang L, Zhang H, Wang Y, Gao J, Zhao M, Zhang K.   +9 more
europepmc   +1 more source

Unmasking delayed recovery in severe diabetic ketoacidosis: clinical and biochemical clues from early resuscitation. [PDF]

Ann Pediatr Endocrinol Metab
Chung J, Kim B, Cheon CK, Kang JE, Kim Y, Yoo S.   +5 more
europepmc   +1 more source