Results 21 to 30 of about 4,066,847 (276)

An ultrasensitive photoelectrochemical nucleic acid biosensor [PDF]

open access: yes, 2005
A simple and ultrasensitive procedure for non-labeling detection of nucleic acids is described in this study. It is based on the photoelectrochemical detection of target nucleic acids by forming a nucleic acid/photoreporter adduct layer on an ITO ...
Gao, Zhiqiang, Tansil, Natalia C.
core   +3 more sources

A Versatile Ligand Platform that Supports Lewis Acid Promoted Migratory Insertion [PDF]

open access: yes, 2012
A helping hand: Incorporation of Group 2 Lewis acids into a macrocycle appended to a phosphine ligand attached to a rhenium carbonyl complex promotes otherwise unfavorable transformations of coordinated CO (see scheme; M=Ca, Sr).
Bercaw, John E.   +2 more
core   +1 more source

Lipopolysaccharide-specific acyloxyacyl hydrolase [PDF]

open access: yes, 1991
" An acyloxyacyl hydrolase from the human promyelocyte cell line HL-60 has been found to specifically hydrolyze fatty acids from their ester linkages to hydroxy groups of 3-hydroxyfatty acids, the latter being being bound in turn to lipopolysaccharide ...
Hall, Catherine L., Munford, Robert S.
core   +1 more source

Is fat the sixth taste primary? Evidence and implications [PDF]

open access: yes, 2015
Explores our tongue\u27s ability to detect fat as a distinct taste similar to our ability to sense sweet, sour, bitter, acid and savory. Abstract Taste is the chemical sense responsible for the detection of non-volatile chemicals in potential foods. For
Andrew Costanzo, Russell Keast
core   +1 more source

Extracellular vesicle mimetics as delivery vehicles for oligonucleotide-based therapeutics and plasmid DNA

open access: yesFrontiers in Bioengineering and Biotechnology
IntroductionSmall membrane particles called extracellular vesicles (EVs) transport biologically active cargo between cells, providing intercellular communication.
Anastasiya Oshchepkova   +15 more
doaj   +1 more source

Types of Acid and Drying Method Differently Affect the Chemical Profile of Sodium Caseinate

open access: yesJournal of Food Quality and Hazards Control, 2021
Background: Sodium caseinate is a rich source of protein and minerals originating from animals. Numerous food and non-food products are made from sodium caseinate.
F. Maruddin   +5 more
doaj  

Xenogeneic, extracorporeal liver perfusion in primates improves the ratio of branched-chain amino acids to aromatic amino acids (Fischer's ratio) [PDF]

open access: yes, 1999
In fulminant hepatic failure (FHF), the development of hepatic encephalopathy is associated with grossly abnormal concentrations of plasma amino acids (PAA).
Hammer, C.   +7 more
core   +1 more source

Optimization of Bifunctional Antisense Oligonucleotides for Regulation of Mutually Exclusive Alternative Splicing of PKM Gene

open access: yesMolecules, 2022
Oligonucleotide tools, as modulators of alternative splicing, have been extensively studied, giving a rise to new therapeutic approaches. In this article, we report detailed research on the optimization of bifunctional antisense oligonucleotides (BASOs),
Natalia Bartyś   +2 more
doaj   +1 more source

A Comprehensive Analysis of the Thrombin Binding Aptamer Containing Functionalized Pyrrolo-2’-deoxycytidines

open access: yesPharmaceuticals, 2021
Aptamers constitute an answer for the growing need for targeted therapy development. One of the most well-known representatives of this group of compounds is thrombin binding aptamers (TBA) targeted towards thrombin.
Weronika Kotkowiak   +2 more
doaj   +1 more source

A thermodynamic basis for prebiotic amino acid synthesis and the nature of the first genetic code

open access: yes, 2009
Of the twenty amino acids used in proteins, ten were formed in Miller's atmospheric discharge experiments. The two other major proposed sources of prebiotic amino acid synthesis include formation in hydrothermal vents and delivery to Earth via meteorites.
Chakrabarti S.   +2 more
core   +1 more source

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