Results 181 to 190 of about 133,947 (248)

A generalizable method for the purification and biophysical characterization of bacterial membrane receptors

open access: yesProtein Science, Volume 35, Issue 11, November 2026.
Abstract Membrane‐embedded bacterial receptors are challenging to express and purify in soluble form, yet their isolated domains are essential tools for structural and ligand‐discovery studies. Pseudomonas aeruginosa relies on the TonB‐dependent heme receptor HasR for iron acquisition, a process central to its pathogenicity.
Federico Bosetto   +9 more
wiley   +1 more source

Machine Learning–Augmented Precision Dosing: Integrating Pharmacokinetic Modeling With Clinical Decision Support

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 11, November 2026.
ABSTRACT Inter‐individual variability in drug exposure can lead to ineffective therapy or toxicity, particularly in vulnerable patients. Routine model‐informed precision dosing (MIPD) relies mainly on population pharmacokinetic (PopPK) models, Bayesian forecasting, and therapeutic drug monitoring (TDM).
Yunmeng Pang   +5 more
wiley   +1 more source

Combating Campylobacter Resistance in Moroccan Poultry Using Essential Oil–Ciprofloxacin Combination

open access: yesVeterinary Medicine and Science, Volume 12, Issue 6, November 2026.
With an estimated prevalence of 15.52% in Moroccan poultry, Campylobacter species pose a significant food safety concern. We investigated whether essential oils (EOs) could restore the efficacy of ciprofloxacin against multidrug‐resistant (MDR) strains.
Zineb Soubai   +13 more
wiley   +1 more source

Crystal structure of tyrosine‐tRNA synthetase from Helicobacter pylori G27

open access: yesActa Crystallographica Section F, Volume 82, Issue 11, Page 369-375, November 2026.
The production, crystallization and 2.2 Å resolution structure of H. pylori tyrosine‐tRNA synthetase are reported.Helicobacter pylori, a major cause of gastric ulcers and cancers, infects nearly half of the world's population. The crystal structure of a potential H.
David Igbalajobi   +13 more
wiley   +1 more source

Beyond Bactericidal: Plasma Surface Engineering to Defeat Food Matrix‐Conditioning Layers

open access: yesComprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 6, November 2026.
ABSTRACT The persistence of foodborne pathogens on industrial food contact surfaces continues to challenge global food safety despite advances in sanitation technologies. A central limitation of current antimicrobial strategies lies in their validation under simplified laboratory conditions that overlook the physicochemically driven formation of food ...
Rafael Bianchini Fulindi   +2 more
wiley   +1 more source

A retrospective analysis of bacterial pathogens in wounds in an equine hospital (2017–2022)

open access: yesEquine Veterinary Education, Volume 38, Issue 11, Page e910-e918, November 2026.
Summary Background Bacterial infections are a major cause of morbidity in horses, particularly in soft tissue wounds (STW) and surgical site infections (SSI). Rising antimicrobial resistance poses challenges for timely treatment. Knowledge of common pathogens and their resistance patterns is therefore essential.
J. Nebes   +3 more
wiley   +1 more source

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